Determination of the fault plane using a single near-field seismic station with a finite-dimension source model

We explore the possibility of determining the actual fault plane of an earthquake from the inversion of near-source displacement seismograms of one station when a finite-dimension source is used instead of a point source model and when the complete displacement is taken into account, including near-field waves. Tests on synthetic seismograms and real data recorded at local distances show that this is possible even with a single, three-component station. A single accelerogram available for the Erzincan, Turkey, 1992 March 13, Ms= 6.8 earthquake is inverted and the solution found is compatible with other seismological studies and with the mechanism expected for the North Anatolian Faul

A First Step Towards Automatically Building Network Representations

To fully harness Grids, users or middlewares must have some knowledge on the topology of the platform interconnection network. As such knowledge is usually not available, one must uses tools which automatically build a topological network model through some measurements. In this article, we define a methodology to assess the quality of these network model building tools, and we apply this methodology to representatives of the main classes of model builders and to two new algorithms. We show that none of the main existing techniques build models that enable to accurately predict the running time of simple application kernels for actual platforms. However some of the new algorithms we propose give excellent results in a wide range of situations

A continuous low star formation rate in IZw 18 ?

Deep long-slit spectroscopic observations of the blue compact galaxy IZw 18 obtained with the CFH 3.6 m Telescope are presented. The very low value of oxygen abundance previously reported is confirmed and a very homogeneous abundance distribution is found (no variation larger than 0.05 dex) over the whole ionized region. We concur with Tenorio-Tagle (1996) and Devost et al. (1997) that the observed abundance level cannot result from the material ejected by the stars formed in the current burst, and propose that the observed metals were formed in a previous star formation episode. Metals ejected in the current burst of star formation remain most probably hidden in a hot phase and are undetectable using optical spectroscopy. We discuss different scenarios of star formation in IZw 18. Combining various observational facts, for instance the faint star formation rate observed in low surface brightness galaxies van Zee et al. (1997), it is proposed that a low and continuous rate of star formation occurring during quiescent phases between bursts could be a significant source of metal enrichment of the interstellar medium.Comment: 10 pages, 4 Postscript figures, to be published in Astronomy and Astrophysics main journa

Management of hyperkalemia in the acutely ill patient.

PURPOSE:To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. METHODS:We searched MEDLINE and EMBASE for relevant papers published in English between Jan 1, 1938, and July 1, 2018, in accordance with the PRISMA Statement using the following terms: "hyperkalemia," "intensive care," "acute kidney injury," "acute kidney failure," "hyperkalemia treatment," "renal replacement therapy," "dialysis," "sodium bicarbonate," "emergency," "acute." Reports from within the past 10 years were selected preferentially, together with highly relevant older publications. RESULTS:Hyperkalemia is a potentially life-threatening electrolyte abnormality and may cause cardiac electrophysiological disturbances in the acutely ill patient. Frequently used therapies for hyperkalemia may, however, also be associated with morbidity. Therapeutics may include the simultaneous administration of insulin and glucose (associated with frequent dysglycemic complications), β-2 agonists (associated with potential cardiac ischemia and arrhythmias), hypertonic sodium bicarbonate infusion in the acidotic patient (representing a large hypertonic sodium load) and renal replacement therapy (effective but invasive). Potassium-lowering drugs can cause rapid decrease in serum potassium level leading to cardiac hyperexcitability and rhythm disorders. CONCLUSIONS:Treatment of hyperkalemia should not only focus on the ability of specific therapies to lower serum potassium level but also on their potential side effects. Tailoring treatment to the patient condition and situation may limit the risks

Self-harm to preferentially harm the pathogens within: non-specific stressors in innate immunity

Therapies with increasing specificity against pathogens follow the immune system\u27s evolutionary course in maximizing host defence while minimizing self-harm. Nevertheless, even completely non-specific stressors, such as reactive molecular species, heat, nutrient and oxygen deprivation, and acidity can be used to preferentially harm pathogens. Strategic use of non-specific stressors requires exploiting differences in stress vulnerability between pathogens and hosts. Two basic vulnerabilities of pathogens are: (i) the inherent vulnerability to stress of growth and replication (more immediately crucial for pathogens than for host cells) and (ii) the degree of pathogen localization, permitting the host\u27s use of locally and regionally intense stress. Each of the various types of non-specific stressors is present during severe infections at all levels of localization: (i) ultra-locally within phagolysosomes, (ii) locally at the infected site, (iii) regionally around the infected site and (iv) systemically as part of the acute-phase response. We propose that hosts strategically use a coordinated system of non-specific stressors at local, regional and systemic levels to preferentially harm the pathogens within. With the rising concern over emergence of resistance to specific therapies, we suggest more scrutiny of strategies using less specific therapies in pathogen control. Hosts\u27 active use of multiple non-specific stressors is likely an evolutionarily basic defence whose retention underlies and supplements the well-recognized immune defences that directly target pathogens

Probing The Multiphase Interstellar Medium Of The Dwarf Starburst Galaxy NGC 625 With FUSE Spectroscopy

We present new FUSE spectroscopy of the dwarf starburst galaxy NGC 625. These observations probe multiple phases of the interstellar medium, including the coronal, ionized, neutral and molecular gas. This nearby (D = 3.9 +/- 0.2 Mpc) system shows a clear detection of outflowing coronal gas as traced by OVI 1032 Angstrom absorption. The centroid of the OVI profile is blueshifted with respect to the galaxy systemic velocity by ~ 30 km/sec, suggesting a low-velocity outflow. The implied OVI velocity extent is found to be 100 +/- 20 km/sec, which is fully consistent with the detected HI outflow velocity found in radio synthesis observations. We detect multiple lines of diffuse H2 absorption from the ISM of NGC 625; this is one of only a few extragalactic systems with FUSE detections of H2 lines in the Lyman and Werner bands. We find a potential abundance offset between the neutral and nebular gas that exceeds the errors on the derived column densities. Since such an offset has been found in multiple dwarf galaxies, we discuss the implications of a lower-metallicity halo surrounding the central star forming regions of dwarf galaxies. The apparent offset may be due to saturation of the observed OI line, and higher S/N observations are required to resolve this issue.Comment: ApJ, in press; full-resolution version may be obtained at http://www.astro.umn.edu/~cannon/n625.fuse.p

Selective amplification of scars in a chaotic optical fiber

In this letter we propose an original mechanism to select scar modes through coherent gain amplification in a multimode D-shaped fiber. More precisely, we numerically demonstrate how scar modes can be amplified by positioning a gain region in the vicinity of specific points of a short periodic orbit known to give rise to scar modes

Ultrastructural characteristics of glucocorticoid-induced osteoporosis

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