131 research outputs found

    Controllability of second-order neutral functional differential inclusions in Banach spaces

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    AbstractIn this paper, we prove the controllability of second-order neutral functional differential inclusions in Banach spaces. The result are obtained by using the theory of strongly continuous cosine families and a fixed point theorem for condensing maps due to Martelli

    Quercetin, the active phenolic component in kiwifruit, prevents hydrogen peroxide-induced inhibition of gap-junction intercellular communication

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    We evaluated the effects of the two main kiwifruit cultivars (gold kiwifruit (GOK) and green kiwifruit (GRK)) and their active phenolic compound, quercetin, on H2O2-induced inhibition of gap-junction intercellular communication (GJIC) in WB-F344 rat liver epithelial cells. We found that both GOK and GRK protect WB-F344 cells from H2O2-induced inhibition of GJIC. The extracellular signal-regulated protein kinase 1/2 (ERK1/2)-connexin 43 (Cx43) signalling pathway is crucial for the regulation of GJIC, and both GOK and GRK blocked the H2O2-induced phosphorylation of Cx43 and ERK1/2 in WB-F344 cells. Quercetin alone attenuated the H2O2-mediated ERK1/2-Cx43 signalling pathway and consequently reversed H2O2-mediated inhibition of GJIC in WB-F344 cells. A free radical-scavenging assay using 1,1-diphenyl-2-picrylhydrazyl showed that the scavenging activity of quercetin was higher than that of a synthetic antioxidant, butylated hydroxytoluene, per mol, suggesting that the chemopreventive effect of quercetin on H2O2-mediated inhibition of ERK1/2-Cx43 signalling and GJIC may be mediated through its free radical-scavenging activity. Since the carcinogenicity of reactive oxygen species such as H2O2 is attributable to the inhibition of GJIC, GOK, GRK and quercetin may have chemopreventive potential by preventing the inhibition of GJI

    Giant Cell Tumor of Soft Tissue: a Case with Atypical US and MRI Findings

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    We report the case of a giant cell tumor with diffuse interstitial hemorrhaging and unusually prominent cystic components in the soft tissue of the thigh which has not been reported previously. Magnetic resonance image (MRI), showed signal intensity typical of a giant cell tumor. However, because of its conspicuous large well-circumscribed cystic components, the differential diagnoses, based on the image findings from an ultrasonography (US) and MRI, were complicated epidermoid cyst, cystic change of a neurogenic tumor, and a parasitic cyst

    Epidermal growth factor receptor mutations and anaplastic lymphoma kinase rearrangements in lung cancer with nodular ground-glass opacity

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    VÄr uppsats handlar om formativ bedömning och vad det innebÀr att arbeta sÄ i undervisningen. Vi tolkar att rÄdande lÀroplaner beskriver ett uppdrag som ligger i linje med ett formativt arbetssÀtt. Syftet var att ta reda pÄ om lÀrare i samhÀllskunskap som arbetar pÄ gymnasiet arbetar formativt och hur de gör det. Ett annat vanligt namn för formativ bedömning Àr bedömning för lÀrande (BFL). Genom kvalitativa intervjuer har vi frÄgat gymnasielÀrare i samhÀllskunskap hur de arbetar med bedömning, om de arbetar formativt och om det finns nÄgon samsyn pÄ deras respektive gymnasieskolor kring bedömning. Vi ville ocksÄ veta vad formativt arbete innebÀr. Bedömning för lÀrande fokuserar pÄ lÀrandet och hur eleven kan utvecklas och nÄ framgÄng i lÀrandet. Genom att konkretisera mÄl, syfte och kunskapskvaliteter sÄ att eleven förstÄr dessa kan eleven fÄ syn pÄ sitt eget lÀrande. NÀr eleven ges makt över sitt eget lÀrande leder det till ökad motivation. I formativ bedömning arbetar lÀraren bland annat med feedback och kamrat- och sjÀlvvÀrdering. VÄrt resultat visar att lÀrarna vi intervjuat i stor utstrÀckning arbetar summativt med formativa inslag i varierande grad, förutom en av lÀrarna som arbetar pÄ en gymnasieskola i BorÄs som arbetar enligt bedömning för lÀrande. Studien visar att det rÄder brist pÄ samsyn kring bedömning pÄ gymnasie-skolorna, förutom pÄ skolan i BorÄs dÀr det finns tid avsatt för möten och samtal kring formativ bedömning. Litteraturen visar pÄ de positiva effekterna av bedömning för lÀrande vilket ocksÄ styrks av intervjun med lÀraren i BorÄs

    Herpes Simplex Virus Type 2 Seroprevalence in Korea: Rapid Increase of HSV-2 Seroprevalence in the 30s in the Southern Part

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    To determine the characteristics of seroprevalence of herpes simplex virus type 2 (HSV-2) infection among Korean people, a cross-sectional study was conducted on three groups in 2004. The three groups consisted of the general public who visited public health centers, commercial sex workers (CSWs), and human immunodeficiency virus (HIV)-infected persons. Among the general public, HSV-2 seroprevalence rates for age under the 20s, in the 20s, 30s, 40s and the above 22.6%, 32.7% and 32.3%, respectively, which showed rapid increase of the rate in the 30s (p<0.0001). In case of the above of 19 yr old, women (28.0%) was higher than men (21.7%) (p<0.0001). The rate of CSWs (81.6%) was about 10 times higher than that of general women. In case of HIV-infected men (47.6%), the figure was about 2-3 times higher than that of general men. The low rate in the teens and the 20s proved that it is essential to develop sexually transmitted infections (STIs) prevention programs of education and publicity for them as a precaution measure. This study is the first major study of its kind on HSV-2 and would provide basic data for prevention of STIs including information about target groups subject to vaccination program

    The Feasibility and Safety of the Endoscopic Submucosal Dissection of Superficial Gastric Neoplastic Lesions in Patients with Compensated Liver Cirrhosis: A Retrospective Study

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