What Was Really Accomplished Today? Mathematics Content Specialists Observe a Class for Prospective K-8 Teachers

One of the important activities mathematics teacher educators engage in is the development of teachers at both the in-service and pre-service levels. Also of importance is the professional development of these professional developers. In the summer of 2004, a summer institute was held that allowed mathematics teacher educators watch the teaching of a mathematics content course for prospective K-8 teachers. This paper examines the manner in which a specific group of mathematics content specialists experienced this professional development

The Negative Relationship between Religiosity and Substance Use

The negative association between religiosity and substance abuse is well established in previous literature. Scholarly research continues to find support for both intrinsic and extrinsic religiosity functioning as protective factors against substance abuse with intrinsic religiosity’s negative correlation with substance use being more established in literature than extrinsic religiosity. This study focuses on the relationship between college student intrinsic and extrinsic religiosity, measured by the Intrinsic/Extrinsic Religiosity Scale and substance use, measured by the Texas Christian University Drug Screen-5 (TCUDS-5). The Intrinsic/Extrinsic Religiosity Scale and the TCUDS-5 are well established instruments with historically high internal consistency. We hypothesized that there was a negative correlation between religiosity scores and substance use scores among our population. Additionally, we hypothesized that intrinsic religiosity would have a stronger relationship with substance use than extrinsic religiosity would. In order to test our hypothesis, a survey was administered to undergraduate students at a university in the southeast. After cleaning the data, our total sample consisted of 386 students. Of those surveyed, 256 are female, 127 are male, and 1 classified other. The majority of the population identified as White (n = 328), followed by Black (n = 28), Hispanic (n = 23), and Asian, Native American/Pacific Islander, Multiracial, or Other (n = 7). All students received extra credit as an incentive to voluntarily complete a larger battery of measures related to habits and addiction. However, this analysis will only include the Intrinsic/Extrinsic Religiosity Scale (M = 12.019, SD = 5.55) and the TCUDS-5 (M = 0.762, SD = 2.004). A Pearson correlation was completed to determine whether there was a statistically significant relationship between religiosity and substance use in college students. All analyses were conducted using JASP. Results supported our hypothesis with findings indicating evidence for a statistically significant negative correlation between intrinsic religiosity and substance abuse (r = -.142, p = .005). Our hypothesis that extrinsic religiosity will not be as strongly related to substance use as intrinsic religiosity was supported for social extrinsic religiosity (r = -.121, p =.018), but not supported for personal extrinsic religiosity measure (r = -.15, p =.002). The results of this study contribute to the converging evidence that intrinsic religiosity is inversely related to substance use and could serve as a protective factor against problematic substance use. Those who have internalized their faith may rely on faith to cope with stress rather than use substances or restrict use due to religious beliefs. Thus, this study provides potential support for the theory that religiosity is a protective factor against substance use disorders. Future research should investigate the longitudinal impact of religiosity on substance use in college students and other populations

Novel Human Rhinoviruses and Exacerbation of Asthma in Children1

To determine links between human rhinoviruses (HRV) and asthma, we used data from a case–control study, March 2003–February 2004, among children with asthma. Molecular characterization identified several likely new HRVs and showed that association with asthma exacerbations was largely driven by HRV-A and a phylogenetically distinct clade of 8 strains, genogroup C

Cooperativity of Kv7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells.

The mammalian cochlea relies on active electromotility of outer hair cells (OHCs) to resolve sound frequencies. OHCs use ionic channels and somatic electromotility to achieve the process. It is unclear, though, how the kinetics of voltage-gated ionic channels operate to overcome extrinsic viscous drag on OHCs at high frequency. Here, we report ultrafast electromechanical gating of clustered Kv7.4 in OHCs. Increases in kinetics and sensitivity resulting from cooperativity among clustered-Kv7.4 were revealed, using optogenetics strategies. Upon clustering, the half-activation voltage shifted negative, and the speed of activation increased relative to solitary channels. Clustering also rendered Kv7.4 channels mechanically sensitive, confirmed in consolidated Kv7.4 channels at the base of OHCs. Kv7.4 clusters provide OHCs with ultrafast electromechanical channel gating, varying in magnitude and speed along the cochlea axis. Ultrafast Kv7.4 gating provides OHCs with a feedback mechanism that enables the cochlea to overcome viscous drag and resolve sounds at auditory frequencies

Debating DSM-5:diagnosis and the sociology of critique

The development of the fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders—the DSM-5—has reenergised and driven further forward critical discourse about the place and role of diagnosis in mental health. The DSM-5 has attracted considerable criticism, not least about its role in processes of medicalisation. This paper suggests the need for a sociology of psychiatric critique. Sociological analysis can help map fields of contention, and cast fresh light on the assumptions and nuances of debate around the DSM-5; it underscores the importance of diagnosis to the governance of social and clinical life, as well as the wider discourses critical commentaries connect with and are activated by. More normatively, a sociology of critique can indicate which interests and values are structuring the dialogues being articulated, and just how diverse clinical opinion regarding the DSM can actually be. This has implications for the considerations of health services and policy decision-makers who might look to such debates for guidance

Allergen immunotherapy on the way to product-based evaluation - a WAO statement

Allergen immunotherapy (AIT) is widely used in clinical practice for patients with moderate to severe allergic rhinitis due to inhalant allergens and may be delivered via subcutaneous (SCIT) and sublingual routes (SLIT). However, the quality of evidence for individual AIT products is very heterogeneous, and extensions of overall conclusions ("class effects") on the efficacy and disease-modifying effects to all AIT products are unjustified. In contrast, each product needs to be evaluated individually, based on available study results, to justify efficacy and specific claims on sustained and disease modifying effects per allergen and targeted patient group (children vs. adults, allergic rhinitis vs. asthma). WAO intends to support the current development to evidence-based AIT, which ultimately will lead to a more efficacious treatment of allergic patients and the appropriate recognition of AIT

RICE Limits on the Diffuse Ultra-High Energy Neutrino Flux

We present new limits on ultra-high energy neutrino fluxes above 100 PeV based on data collected by the Radio Ice Cherenkov Experiment (RICE) at the South Pole from 1999-2005. We discuss estimation of backgrounds, calibration and data analysis algorithms (both on-line and off-line), procedures used for the dedicated neutrino search, and refinements in our Monte Carlo (MC) simulation, including recent in situ measurements of the complex ice dielectric constant. An enlarged data set and a more detailed study of hadronic showers results in a sensitivity improvement of more than one order of magnitude compared to our previously published results. Examination of the full RICE data set yields zero acceptable neutrino candidates, resulting in 95% confidence-level model dependent limits on the flux (E_\nu)^2(d\phi/dE_\nu)<10^{-6} GeV/(cm^2s~sr}) in the energy range 10^{17}< E_\nu< 10^{20} eV. The new RICE results rule out the most intense flux model projections at 95% confidence level.Comment: Submitted to Astropart. Phy

Design summary of the magnet support structures for the proton storage ring injection line upgrade

This report summarizes the technical engineering and design issues associated with the Proton Storage Ring (PSR) Injection Line upgrade of the Los Alamos Neutron Science Center (LANSCE). The main focus is on the engineering design calculations of several magnet support structures. The general procedure based upon a set number of design criteria is outlined, followed by a case-by-case summary of the engineering design analyses, reutilization or fabrication callouts and design safety factors

Intermediate Tail Dependence: A Review and Some New Results

The concept of intermediate tail dependence is useful if one wants to quantify the degree of positive dependence in the tails when there is no strong evidence of presence of the usual tail dependence. We first review existing studies on intermediate tail dependence, and then we report new results to supplement the review. Intermediate tail dependence for elliptical, extreme value and Archimedean copulas are reviewed and further studied, respectively. For Archimedean copulas, we not only consider the frailty model but also the recently studied scale mixture model; for the latter, conditions leading to upper intermediate tail dependence are presented, and it provides a useful way to simulate copulas with desirable intermediate tail dependence structures.Comment: 25 pages, 1 figur

Detecting a conditional extrme value model

In classical extreme value theory probabilities of extreme events are estimated assuming all the components of a random vector to be in a domain of attraction of an extreme value distribution. In contrast, the conditional extreme value model assumes a domain of attraction condition on a sub-collection of the components of a multivariate random vector. This model has been studied in \cite{heffernan:tawn:2004,heffernan:resnick:2007,das:resnick:2008a}. In this paper we propose three statistics which act as tools to detect this model in a bivariate set-up. In addition, the proposed statistics also help to distinguish between two forms of the limit measure that is obtained in the model.Comment: 21 pages, 4 figure