589 research outputs found
An adaptive inelastic magnetic mirror for Bose-Einstein condensates
We report the reflection and focussing of a Bose-Einstein condensate by a new
pulsed magnetic mirror. The mirror is adaptive, inelastic, and of extremely
high optical quality. The deviations from specularity are less than 0.5 mrad
rms, making this the best atomic mirror demonstrated to date. We have also used
the mirror to realize the analog of a beam-expander, producing an ultra-cold
collimated fountain of matter wavesComment: 4 pages, 4 figure
Irreversible fate commitment in the Arabidopsis stomatal lineage requires a Fama and Retinoblastoma-related module
The presumed totipotency of plant cells leads to questions about how specific stem cell lineages and terminal fates could be established. In the Arabidopsis stomatal lineage, a transient self-renewing phase creates precursors that differentiate into one of two epidermal cell types, guard cells or pavement cells. We found that irreversible differentiation of guard cells involves RETINOBLASTOMA-RELATED (RBR) recruitment to regulatory regions of master regulators of stomatal initiation, facilitated through interaction with a terminal stomatal lineage transcription factor, FAMA. Disrupting physical interactions between FAMA and RBR preferentially reveals the role of RBR in enforcing fate commitment over its role in cell-cycle control in this developmental context. Analysis of the phenotypes linked to the modulation of FAMA and RBR sheds new light on the way iterative divisions and terminal differentiation are coordinately regulated in a plant stem-cell lineage. - See more at: http://elifesciences.org/content/3/e03271#sthash.f3srCCrx.dpu
Velocity-selective sublevel resonance of atoms with an array of current-carrying wires
Resonance transitions between the Zeeman sublevels of optically-polarized Rb
atoms traveling through a spatially periodic magnetic field are investigated in
a radio-frequency (rf) range of sub-MHz. The atomic motion induces the
resonance when the Zeeman splitting is equal to the frequency at which the
moving atoms feel the magnetic field oscillating. Additional temporal
oscillation of the spatially periodic field splits a motion-induced resonance
peak into two by an amount of this oscillation frequency. At higher oscillation
frequencies, it is more suitable to consider that the resonance is mainly
driven by the temporal field oscillation, with its velocity-dependence or
Doppler shift caused by the atomic motion through the periodic field. A
theoretical description of motion-induced resonance is also given, with
emphasis on the translational energy change associated with the internal
transition.Comment: 7 pages, 3 figures, final versio
Lattice distortions in a sawtooth chain with Heisenberg and Ising bonds
An exactly solvable model of the sawtooth chain with Ising and Heisenberg
bonds and with coupling to lattice distortion for Heisenberg bonds is
considered in the magnetic field. Using the direct transfer-matrix formalism an
exact description of the thermodynamic functions is obtained. The ground state
phase diagrams for all regions of parameters values containing phases
corresponding to the magnetization plateaus at and 1/2 have been
obtained. Exact formulas for bond distortions for various ground states are
presented. A novel mechanism of magnetization plateau stabilization
corresponding to state is reported.Comment: 16 pages, 12 figure
Families’ perceptions of and experiences related to a pediatric weight management program.
Objective: To examine parents' and children's perceptions of and experiences related to a Parents as Agents of Change (PAC) intervention for managing pediatric obesity. Methods: Ten families were recruited from a PAC intervention. Participants were interviewed before (10 adults and 9 children), during (9 adults and 8 children), and after (8 adults) the intervention. Results: Before the intervention, families reported goals to increase physical activity, plan and eat healthier meals, reduce screen time, and lose weight. During the intervention, families described different approaches to making behavior changes depending on who assumed responsibility (parent, child, or shared responsibility). After the intervention, group setting, goal setting, and portion size activities were viewed positively. Suggestions for improvement included engaging children and reducing intervention length. Conclusions and Implications: Practitioners delivering PAC interventions should discuss families' goals and concerns, and who is responsible for making lifestyle changes. Practical activities are valuable. The length of interventions and engagement of children should be considere
Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities
We performed the first proteogenomic study on a prospectively collected colon cancer cohort. Comparative proteomic and phosphoproteomic analysis of paired tumor and normal adjacent tissues produced a catalog of colon cancer-associated proteins and phosphosites, including known and putative new biomarkers, drug targets, and cancer/testis antigens. Proteogenomic integration not only prioritized genomically inferred targets, such as copy-number drivers and mutation-derived neoantigens, but also yielded novel findings. Phosphoproteomics data associated Rb phosphorylation with increased proliferation and decreased apoptosis in colon cancer, which explains why this classical tumor suppressor is amplified in colon tumors and suggests a rationale for targeting Rb phosphorylation in colon cancer. Proteomics identified an association between decreased CD8 T cell infiltration and increased glycolysis in microsatellite instability-high (MSI-H) tumors, suggesting glycolysis as a potential target to overcome the resistance of MSI-H tumors to immune checkpoint blockade. Proteogenomics presents new avenues for biological discoveries and therapeutic development
Search for the Flavor-Changing Neutral Current Decay with the HERA-B Detector
We report on a search for the flavor-changing neutral current decay using events recorded with a dimuon trigger in
interactions of 920 GeV protons with nuclei by the HERA-B experiment. We find
no evidence for such decays and set a 90% confidence level upper limit on the
branching fraction .Comment: 17 pages, 4 figures (of which 1 double), paper to be submitted to
Physics Letters
Measurement of the J/Psi Production Cross Section in 920 GeV/c Fixed-Target Proton-Nucleus Interactions
The mid-rapidity (dsigma_(pN)/dy at y=0) and total sigma_(pN) production
cross sections of J/Psi mesons are measured in proton-nucleus interactions.
Data collected by the HERA-B experiment in interactions of 920 GeV/c protons
with carbon, titanium and tungsten targets are used for this analysis. The
J/Psi mesons are reconstructed by their decay into lepton pairs. The total
production cross section obtained is sigma_(pN)(J/Psi) = 663 +- 74 +- 46
nb/nucleon. In addition, our result is compared with previous measurements
Recent Advances in Understanding Particle Acceleration Processes in Solar Flares
We review basic theoretical concepts in particle acceleration, with
particular emphasis on processes likely to occur in regions of magnetic
reconnection. Several new developments are discussed, including detailed
studies of reconnection in three-dimensional magnetic field configurations
(e.g., current sheets, collapsing traps, separatrix regions) and stochastic
acceleration in a turbulent environment. Fluid, test-particle, and
particle-in-cell approaches are used and results compared. While these studies
show considerable promise in accounting for the various observational
manifestations of solar flares, they are limited by a number of factors, mostly
relating to available computational power. Not the least of these issues is the
need to explicitly incorporate the electrodynamic feedback of the accelerated
particles themselves on the environment in which they are accelerated. A brief
prognosis for future advancement is offered.Comment: This is a chapter in a monograph on the physics of solar flares,
inspired by RHESSI observations. The individual articles are to appear in
Space Science Reviews (2011
Segregation in the twenty first century: Processes, complexities and future directions
Economic inequality, international migration and urban transformation have generated fresh interest in segregation and given new social significance to questions of socio‐spatial separation and interaction. At the same time, advances in data, methods and theory are opening up new avenues of inquiry that push the focus beyond simple measures of unevenness of residential patterns towards more nuanced analysis of spatial asymmetry, structure and scale. There is also a drive towards considering spaces and activities outside the neighbourhood, bringing new richness to our understanding of how various social groups interact in the various aspects of their lives. These processes and complexities form the backdrop for our special issue and we reflect on the implications for future priorities in research on segregation in the twenty first century
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