723 research outputs found

    Study of resonance light scattering for remote optical probing

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    Enhanced scattering and fluorescence processes in the visible and UV were investigated which will enable improved remote measurements of gas properties. The theoretical relationship between scattering and fluorescence from an isolated molecule in the approach to resonance is examined through analysis of the time dependence of re-emitted light following excitation of pulsed incident light. Quantitative estimates are developed for the relative and absolute intensities of fluorescence and resonance scattering. New results are obtained for depolarization of scattering excited by light at wavelengths within a dissociative continuum. The experimental work was performed in two separate facilities. One of these utilizes argon and krypton lasers, single moded by a tilted etalon, and a 3/4 meter double monochromator. This facility was used to determine properties of the re-emission from NO2, I2 and O3 excited by visible light. The second facility involves a narrow-line dye laser, and a 3/4 meter single monochromator. The dye laser produces pulsed light with 5 nsec pulse duration and 0.005 nm spectral width

    Performance modeling of ultraviolet Raman lidar systems for daytime profiling of atmospheric water vapor

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    We describe preliminary results from a comprehensive computer model developed to guide optimization of a Raman lidar system for measuring daytime profiles of atmospheric water vapor, emphasizing an ultraviolet, solar-blind approach

    A Positive Relationship Between Religious Faith and Forgiveness: Faith in the Absence of Data?

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    Religious faith and beliefs appear to play an important role in the lives of many individuals and are the topic of much research. The present study investigated the relationship between religious faith and forgiveness in a sample (n = 196) of college students. Students were asked to complete the Heartland Forgiveness Scale and the Santa Clara Strength of Religious Faith Questionnaire. Analyses of scores on both measures revealed a positive, significant correlation between these constructs, suggesting that there is a meaningful relationship between religious faith and the tendency to forgive. Implications and directions for further research are discussed

    A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody.

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    The CCR5 receptor plays a role in several key physiological and pathological processes and is an important therapeutic target. Inhibition of the CCR5 axis by passive or active immunisation offers one very selective strategy for intervention. In this study we define a new linear epitope within the extracellular domain of CCR5 recognised by two independently produced monoclonal antibodies. A short peptide encoding the linear epitope can induce antibodies which recognise the intact receptor when administered colinear with a tetanus toxoid helper T cell epitope. The monoclonal antibody RoAb 13 is shown to bind to both cells and peptide with moderate to high affinity (6x10^8 and 1.2x107 M-1 respectively), and binding to the peptide is enhanced by sulfation of tyrosines at positions 10 and 14. RoAb13, which has previously been shown to block HIV infection, also blocks migration of monocytes in response to CCR5 binding chemokines and to inflammatory macrophage conditioned medium. A Fab fragment of RoAb13 has been crystallised and a structure of the antibody is reported to 2.1 angstrom resolution

    Summary of the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1)

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    Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built. To highlight some of these issues and share experiences, the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1) was held in November 2013 in conjunction with the SC13 Conference. The workshop featured keynote presentations and a large number (54) of solicited extended abstracts that were grouped into three themes and presented via panels. A set of collaborative notes of the presentations and discussion was taken during the workshop. Unique perspectives were captured about issues such as comprehensive documentation, development and deployment practices, software licenses and career paths for developers. Attribution systems that account for evidence of software contribution and impact were also discussed. These include mechanisms such as Digital Object Identifiers, publication of “software papers”, and the use of online systems, for example source code repositories like GitHub. This paper summarizes the issues and shared experiences that were discussed, including cross-cutting issues and use cases. It joins a nascent literature seeking to understand what drives software work in science, and how it is impacted by the reward systems of science. These incentives can determine the extent to which developers are motivated to build software for the long-term, for the use of others, and whether to work collaboratively or separately. It also explores community building, leadership, and dynamics in relation to successful scientific software

    A diffusion-induced transition in the phase separation of binary fluid mixtures subjected to a temperature ramp

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    Demixing of binary fluids subjected to slow temperature ramps shows repeated waves of nucleation which arise as a consequence of the competition between generation of supersaturation by the temperature ramp and relaxation of supersaturation by diffusive transport and flow. Here, we use an advection-reaction-diffusion model to study the oscillations in the weak- and strong-diffusion regime. There is a sharp transition between the two regimes, which can only be understood based on the probability distribution function of the composition rather than in terms of the average composition. We argue that this transition might be responsible for some yet unclear features of experiments, like the appearance of secondary oscillations and bimodal droplet size distributions.Comment: 6 pages, 3 color figure

    Optimization of the design of OMNIS, the observatory of multiflavor neutrinos from supernovae

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    A Monte Carlo code has been developed to simulate the operation of the planned detectors in OMNIS, a supernova neutrino observatory. OMNIS will detect neutrinos originating from a core collapse supernova by the detection of spalled neutrons from Pb- or Fe-nuclei. This might be accomplished using Gd-loaded liquid scintillator. Results for the optimum configuration for such modules with respect to both neutron detection efficiency and cost efficiency are presented. Careful consideration has been given to the expected levels of radioactive backgrounds and their effects. The results show that the amount of data to be processed by a software trigger can be reduced to the <10kHz region and a neutron, once produced in the detector, can be detected and identified with an efficiency of >30%.Comment: Elsevier preprint; 29 pages, 23 figure
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