Saylorville Summer

While performing the underclassman ritual of scanning the Bessey bulletin board one December day two years ago, I saw a U.S. Army Corps of Engineers Notice: Park Tech- G5- 04.05.Duties as follows: Law-enforcement, visitor assistance, patrol of recreation areas by car and boat, other duties as assigned. Til this point I had been flushed by every major resource agency in the United States, and with only volunteer positions to fall back on, the though of a lean fall semester of unpaid utility bills weighed heavily on my mind. I walked down to Dr. Jungst\u27s office, picked up a SF171, typed it up and waited. The Corps officials were to be at a recreation job fair on campus, and that was when I was to make my pitch

Widths of Isobaric Analog Resonances: a microscopic approach

A self-consistent particle-phonon coupling model is used to investigate the properties of the isobaric analog resonance in $^{208}$Bi. It is shown that quantitative agreement with experimental data for the energy and the width can be obtained if the effects of isospin-breaking nuclear forces are included, in addition to the Coulomb force effects. A connection between microscopic model predictions and doorway state approaches which make use of the isovector monopole resonance, is established via a phenomenological ansatz for the optical potential.Comment: 18 pages, 1 figure. To appear on Phys. Rev. C (tentatively scheduled for June 1998

Global Dimension of Polynomial Rings in Partially Commuting Variables

For any free partially commutative monoid $M(E,I)$, we compute the global dimension of the category of $M(E,I)$-objects in an Abelian category with exact coproducts. As a corollary, we generalize Hilbert's Syzygy Theorem to polynomial rings in partially commuting variables.Comment: 11 pages, 2 figure

Coupled-channel effective field theory and proton-7^7Li scattering

We apply the renormalisation group (RG) to analyse scattering by short-range forces in systems with coupled channels. For two S-wave channels, we find three fixed points, corresponding to systems with zero, one or two bound or virtual states at threshold. We use the RG to determine the power countings for the resulting effective field theories. In the case of a single low-energy state, the resulting theory takes the form of an effective-range expansion in the strongly interacting channel. We also extend the analysis to include the effects of the Coulomb interaction between charged particles. The approach is then applied to the coupled $p+{^7}$Li and $n+{^7}$Be channels which couple to a $J^P=2^-$ state of $^8$Be very close to the $n+{^7}$Be threshold. At next-to-leading order, we are able to get a good description of the $p+{^7}$Li phase shift and the ${^7}$Be(n,p)${^7}$Li cross section using four parameters. Fits at one order higher are similarly good but the available data are not sufficient to determine all five parameters uniquely.Comment: 22 pages, 2 figures, RevTeX4, typos corrected, accepted for publication in European Physical Journal

Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system.

Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection. One of the principal factors that control the outcome of infection is the localized tissue response and subsequent immune response directed against the invading toxic agent. It is the role of the immune system to contain and control the spread of virus infection in the central nervous system (CNS), and paradoxically, this response may also be pathologic. Chemokines are potent proinflammatory molecules whose expression within virally infected tissues is often associated with protection and/or pathology which correlates with migration and accumulation of immune cells. Indeed, studies with a neurotropic murine coronavirus, mouse hepatitis virus (MHV), have provided important insight into the functional roles of chemokines and chemokine receptors in participating in various aspects of host defense as well as disease development within the CNS. This chapter will highlight recent discoveries that have provided insight into the diverse biologic roles of chemokines and their receptors in coordinating immune responses following viral infection of the CNS

Breakup reaction models for two- and three-cluster projectiles

Breakup reactions are one of the main tools for the study of exotic nuclei, and in particular of their continuum. In order to get valuable information from measurements, a precise reaction model coupled to a fair description of the projectile is needed. We assume that the projectile initially possesses a cluster structure, which is revealed by the dissociation process. This structure is described by a few-body Hamiltonian involving effective forces between the clusters. Within this assumption, we review various reaction models. In semiclassical models, the projectile-target relative motion is described by a classical trajectory and the reaction properties are deduced by solving a time-dependent Schroedinger equation. We then describe the principle and variants of the eikonal approximation: the dynamical eikonal approximation, the standard eikonal approximation, and a corrected version avoiding Coulomb divergence. Finally, we present the continuum-discretized coupled-channel method (CDCC), in which the Schroedinger equation is solved with the projectile continuum approximated by square-integrable states. These models are first illustrated by applications to two-cluster projectiles for studies of nuclei far from stability and of reactions useful in astrophysics. Recent extensions to three-cluster projectiles, like two-neutron halo nuclei, are then presented and discussed. We end this review with some views of the future in breakup-reaction theory.Comment: Will constitute a chapter of "Clusters in Nuclei - Vol.2." to be published as a volume of "Lecture Notes in Physics" (Springer

Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations

Reconstructing lineage relationships in complex tissues can reveal mechanisms underlying development and disease. Recent methods combine single-cell transcriptomics with mitochondrial DNA variant detection to establish lineage relationships in primary human cells, but are not scalable to interrogate complex tissues. To overcome this limitation, here we develop a technology for high-confidence detection of mitochondrial mutations from high-throughput single-cell RNA-sequencing. We use the new method to identify skewed immune cell expansions in primary human clonal hematopoiesis

A note on the Sagnac effect and current terrestrial experiments

We focus on the Sagnac effect for light beams in order to evaluate if the higher-order relativistic corrections of kinematic origin could be relevant for actual terrestrial experiments. Moreover, we discuss to what extent the analogy with the Aharonov-Bohm effect holds true in a fully relativistic framework. We show that the analogy with the Aharonov-Bohm is not true in general, but is recovered in a suitable low-order approximation, and that even though the Sagnac effect is influenced by both the position of the interferometer in the rotating frame and its extension, these effects are negligible for current terrestrial experiment

A method to calculate correlation functions for β=1\beta=1 random matrices of odd size

The calculation of correlation functions for $\beta=1$ random matrix ensembles, which can be carried out using Pfaffians, has the peculiar feature of requiring a separate calculation depending on the parity of the matrix size N. This same complication is present in the calculation of the correlations for the Ginibre Orthogonal Ensemble of real Gaussian matrices. In fact the methods used to compute the $\beta=1$, N odd, correlations break down in the case of N odd real Ginibre matrices, necessitating a new approach to both problems. The new approach taken in this work is to deduce the $\beta=1$, N odd correlations as limiting cases of their N even counterparts, when one of the particles is removed towards infinity. This method is shown to yield the correlations for N odd real Gaussian matrices.Comment: 20 pages, corrected typo