776 research outputs found
Hover performance tests of baseline metal and Advanced Technology Blade (ATB) rotor systems for the XV-15 tilt rotor aircraft
Rotor hover performance data were obtained for two full-scale rotor systems designed for the XV-15 Tilt Rotor Research Aircraft. One rotor employed the rectangular planform metal blades (rotor solidity = 0.089) which were used on the initial flight configuration of the XV-15. The second rotor configuration examined the nonlinear taper, composite-construction, Advanced Technology Blade (ATB), (rotor solidity = 0.10) designed to replace the metal blades on the XV-15. Variations of the baseline ATB tip and cuff shapes were also tested. A new six-component rotor force and moment balance designed to obtain highly accurate data over a broad range of thrust and torque conditions is described. The test data are presented in nondimensional coefficient form for the performance results, and in dimensional form for the steady and alternating loads. Some wake and acoustic data are also shown
Constraining Gravitino Dark Matter with the Cosmic Microwave Background
We consider super-gravity models in which the lightest supersymmetric
particle (LSP) is a stable gravitino. The next-to-lightest supersymmetric
particle (NLSP) freezes out with its thermal relic density and then decays
after sec, injecting high-energy photons into the cosmic
plasma. These photons heat up the electron plasma which then thermalizes with
the cosmic microwave background (CMB) via Compton scattering, bremsstrahlung
and double-Compton scattering. Contrary to previous studies which assume
instantaneous energy injection, we solve the full kinetic equation for the
photon number density with a source term describing the decay of the NLSP. This
source term is based on the requirement that the injected energy be almost
instantaneously redistributed by Compton scattering, hence leading to a
time-dependent chemical potential. We investigate the case of a stau NLSP and
determine the constraints on the gravitino and stau masses from observations of
the CMB spectrum by assuming that all gravitino LSPs come from stau NLSP
decays. Unlike the analytical approximations, we find that there may be a stau
mass below which the constraint from the CMB spectrum vanishes.Comment: 8 pages, 6 figures, revtex4, replaced to match published versio
The Photon Dispersion as an Indicator for New Physics ?
We first comment on the search for a deviation from the linear photon
dispersion relation, in particular based on cosmic photons from Gamma Ray
Bursts. Then we consider the non-commutative space as a theoretical concept
that could lead to such a deviation, which would be a manifestation of Lorentz
Invariance Violation. In particular we review a numerical study of pure U(1)
gauge theory in a 4d non-commutative space. Starting from a finite lattice, we
explore the phase diagram and the extrapolation to the continuum and infinite
volume. These simultaneous limits - taken at fixed non-commutativity - lead to
a phase of broken Poincare symmetry, where the photon appears to be IR stable,
despite a negative IR divergence to one loop.Comment: 8 pages, 4 figures, talk presented at the VI International Workshop
on the Dark Side of the Universe, Leon (Mexico), June 1-6, 2010. References
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Expression of microRNAs and target proteins in skeletal muscle of rats selectively bred for high and low running capacity
Impairments in mitochondrial function and substrate metabolism are implicated in the etiology of obesity and Type 2 diabetes. MicroRNAs (miRNAs) can degrade mRNA or repress protein translation and have been implicated in the development of such disorders. We used a contrasting rat model system of selectively bred high- (HCR) or low- (LCR) intrinsic running capacity with established differences in metabolic health to investigate the molecular mechanisms through which miRNAs regulate target proteins mediating mitochondrial function and substrate oxidation processes. Quantification of select miRNAs using the rat miFinder miRNA PCR array revealed differential expression of 15 skeletal muscles (musculus tibialis anterior) miRNAs between HCR and LCR rats (14 with higher expression in LCR; P < 0.05). Ingenuity Pathway Analysis predicted these altered miRNAs to collectively target multiple proteins implicated in mitochondrial dysfunction and energy substrate metabolism. Total protein abundance of citrate synthase (CS; miR-19 target) and voltage-dependent anion channel 1 (miR-7a target) were higher in HCR compared with LCR cohorts (~57 and ~26%, respectively; P < 0.05). A negative correlation was observed for miR-19a-3p and CS (r = 0.32, P = 0.015) protein expression. To determine whether miR-19a-3p can regulate CS in vitro, we performed luciferase reporter and transfection assays in C2C12 myotubes. MiR-19a-3p binding to the CS untranslated region did not change luciferase reporter activity; however, miR-19a-3p transfection decreased CS protein expression (∼70%; P < 0.05). The differential miRNA expression targeting proteins implicated in mitochondrial dysfunction and energy substrate metabolism may contribute to the molecular basis, mediating the divergent metabolic health profiles of LCR and HCR rat
Innovations in Teacher Development for the Knowledge Age
Lamon is a senior research scientist with the Institute for Knowledge Innovation and Technology (IKIT) and the Ontario Institute for Studies in Education of the University of Toronto. She has been with IKIT since 1996 where she was involved in the Canadian Telelearning National Centres of Excellence program designed to research information and communications technology development in K-12 education. Previously, Lamon directed the international Schools for Thought program, that integrated cognitive research from OISE/UT, Vanderbilt University and the University of California at Berkeley.
Lamon received a PhD in experimental cognitive psychology from the University of Toronto. Her research as a McDonnell post-doctoral fellow led to research in elementary classrooms where students in CSILE classrooms were encouraged to become self-directed, intentional and reflective learners. Lamon is currently researching the evolution of knowledge building communities, the development of teacher expertise, and on how knowledge building & the creation of improvable artifacts increase literacy as a by-product. She is also working on Scardamalia's “Beyond Best Practice” initiative designed to study and promote innovation across sectors, ages and countries.This seminar explores the relevance and feasibility of networked communities for teacher development in developed as well as developing countries. The research was conducted in the context of a UNESCO policy and planning book addressing two challenges: preparing 15-25 million teachers needed in the next 15 years to meet UNESCO’s Education for All goal; and to address the challenge of increasing teacher competencies needed for the knowledge age. Networked communities are defined as webs of relationships that grow from computer-mediated discussions. The webs grow from conversations among people who share a common connection (e.g., teacher educators or teachers working in the same university, school, district, or discipline) and who may differ in other ways (e.g., teachers in different locations, specializing in different disciplines or pedagogies).published_or_final_versionCentre for Information Technology in Education, University of Hong Kon
Stringy Space-Time Foam and High-Energy Cosmic Photons
In this review, I discuss briefly stringent tests of Lorentz-violating
quantum space-time foam models inspired from String/Brane theories, provided by
studies of high energy Photons from intense celestial sources, such as Active
Galactic Nuclei or Gamma Ray Bursts. The theoretical models predict
modifications to the radiation dispersion relations, which are quadratically
suppressed by the string mass scale, and time delays in the arrival times of
photons (assumed to be emitted more or less simultaneously from the source),
which are proportional to the photon energy, so that the more energetic photons
arrive later. Although the astrophysics at the source of these energetic
photons is still not understood, and such non simultaneous arrivals, that have
been observed recently, might well be due to non simultaneous emission as a
result of conventional physics effects, nevertheless, rather surprisingly, the
observed time delays can also fit excellently the stringy space-time foam
scenarios, provided the space-time defect foam is inhomogeneous. The key
features of the model, that allow it to evade a plethora of astrophysical
constraints on Lorentz violation, in sharp contrast to other field-theoretic
Lorentz-violating models of quantum gravity, are: (i) transparency of the foam
to electrons and in general charged matter, (ii) absence of birefringence
effects and (iii) a breakdown of the local effective lagrangian formalism.Comment: 26 pages Latex, 4 figures, uses special macros. Keynote Lecture in
the International Conference "Recent Developments in Gravity" (NEB14),
Ioannina (Greece) June 8-11 201
Implementing virtual collaborative inquiry practises in a middle-school context
The aim of the present study was to investigate the challenges that relate to the implementation of virtual inquiry practises in middle school. The case was a school course in which a group of Finnish students (N = 14) and teachers (N = 7) completed group inquiries through virtual collaboration, using a web-based learning environment. The task was to accomplish a cross-disciplinary inquiry into cultural issues. The students worked mainly at home and took much responsibility for their course achievements. The investigators analysed the pedagogical design of the course and the content of the participants' interaction patterns in the web-based environment, using qualitative content analysis and social network analysis. The findings suggest that the students succeeded in producing distinctive cultural products, and both the students and the teachers adopted novel roles during the inquiry. The web-based learning environment was used more as a coordination tool for organizing the collaborative work than as a forum for epistemic inquiry. The tension between the school curriculum and the inquiry practises was manifest in the participants' discussions of the assessment criteria of the course.The aim of the present study was to investigate the challenges that relate to the implementation of virtual inquiry practises in middle school. The case was a school course in which a group of Finnish students (N = 14) and teachers (N = 7) completed group inquiries through virtual collaboration, using a web-based learning environment. The task was to accomplish a cross-disciplinary inquiry into cultural issues. The students worked mainly at home and took much responsibility for their course achievements. The investigators analysed the pedagogical design of the course and the content of the participants' interaction patterns in the web-based environment, using qualitative content analysis and social network analysis. The findings suggest that the students succeeded in producing distinctive cultural products, and both the students and the teachers adopted novel roles during the inquiry. The web-based learning environment was used more as a coordination tool for organizing the collaborative work than as a forum for epistemic inquiry. The tension between the school curriculum and the inquiry practises was manifest in the participants' discussions of the assessment criteria of the course.The aim of the present study was to investigate the challenges that relate to the implementation of virtual inquiry practises in middle school. The case was a school course in which a group of Finnish students (N = 14) and teachers (N = 7) completed group inquiries through virtual collaboration, using a web-based learning environment. The task was to accomplish a cross-disciplinary inquiry into cultural issues. The students worked mainly at home and took much responsibility for their course achievements. The investigators analysed the pedagogical design of the course and the content of the participants' interaction patterns in the web-based environment, using qualitative content analysis and social network analysis. The findings suggest that the students succeeded in producing distinctive cultural products, and both the students and the teachers adopted novel roles during the inquiry. The web-based learning environment was used more as a coordination tool for organizing the collaborative work than as a forum for epistemic inquiry. The tension between the school curriculum and the inquiry practises was manifest in the participants' discussions of the assessment criteria of the course.Peer reviewe
IN VITRO CYTOTOXICITY BY A NONTHYMUS-PROCESSED LYMPHOCYTE POPULATION WITH SPECIFICITY FOR A VIRALLY DETERMINED TUMOR CELL SURFACE ANTIGEN
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