High resolution numerical study of the Algiers 2001 flash flood: sensitivity to the upper-level potential vorticity anomaly

From 9 to 11 November 2001, intense cyclogenesis affected the northern coasts of Africa and more particularly the densely populated city of Algiers. During the morning of 10 November, more than 130 mm of precipitation was recorded at Bouzareah and resulted in mudslides which devastated the Bab-el-Oued district. This disaster caused more than 700 casualties and catastrophic damage. Like many other heavy rainstorms in the western Mediterranean, this event was associated with the presence of an upper-level trough materialized by a deep stratospheric intrusion and characterized by high potential vorticity values. In this study, the impact of this synoptic structure on the localization and intensity of the precipitation which affected Algiers is investigated using a potential vorticity (PV) inversion method coupled for the first time with the French non-hydrostatic MESO-NH model. A set of perturbed synoptic environments was designed by slightly modifying the extent and the intensity of the coherent potential vorticity structures in the operational ARPEGE analysis. It is shown that such modifications may have a strong impact on the fine-scale precipitation forecast in the Algiers region, thereby demonstrating the fundamental role played by the potential vorticity anomaly during this exceptional meteorological event

Chiasma

Newspaper reporting on events at the Boston University School of Medicine in the 1960s

Enabling quantitative data analysis through e-infrastructures

This paper discusses how quantitative data analysis in the social sciences can engage with and exploit an e-Infrastructure. We highlight how a number of activities which are central to quantitative data analysis, referred to as ‘data management’, can benefit from e-infrastructure support. We conclude by discussing how these issues are relevant to the DAMES (Data Management through e-Social Science) research Node, an ongoing project that aims to develop e-Infrastructural resources for quantitative data analysis in the social sciences

Rotation and lithium abundance of solar-analog stars. Theoretical analysis of observations

Rotational velocity, lithium abundance, and the mass depth of the outer convective zone are key parameters in the study of the processes at work in the stellar interior, in particular when examining the poorly understood processes operating in the interior of solar-analog stars. We investigate whether the large dispersion in the observed lithium abundances of solar-analog stars can be explained by the depth behavior of the outer convective zone masses, within the framework of the standard convection model based on the local mixing-length theory. We also aims to analyze the link between rotation and lithium abundance in solar-analog stars. We computed a new extensive grid of stellar evolutionary models, applicable to solar-analog stars, for a finely discretized set of mass and metallicity. From these models, the stellar mass, age, and mass depth of the outer convective zone were estimated for 117 solar-analog stars, using Teff and [Fe/H] available in the literature, and the new HIPPARCOS trigonometric parallax measurements. We determine the age and mass of the outer convective zone for a bona fide sample of 117 solar-analog stars. No significant on-to-one correlation is found between the computed convection zone mass and published lithium abundance, indicating that the large A(Li) dispersion in solar analogs cannot be explained by the classical framework of envelope convective mixing coupled with lithium depletion at the bottom of the convection zone. These results illustrate the need for an extra-mixing process to explain lithium behavior in solar-analog stars, such as, shear mixing caused by differential rotation. To derive a more realistic definition of solar-analog stars, as well as solar-twin, it seems important to consider the inner physical properties of stars, such as convection, hence rotation and magnetic properties.Comment: 9 pages, 7 figure

Early adolescence behavior problems and timing of poverty during childhood: A comparison of lifecourse models

Contex

Pennsylvania Folklife Vol. 25, Folk Festival Supplement

• Quilts, Quilts, Quilts • America\u27s Heritage is Endowed with Contributions of the Pennsylvania Dutch • The Hospitality Tent: H is for Help - That\u27s What it\u27s all About • Pottery: A Folk Art Expressing the Most in Simplest Terms • It Never Rains on our Parade - On the Fourth of July • Vegetable Dyeing at the Kutztown Folk Festival • Festival Focus • Folk Festival Program • Festival Foods: The Original Touch of the Dutch • Ursinus College Studies at the Festival • Behind the Scenes of We Like Our Country, But We Love Our God • Reverse Glass Tinsel Painting • Tin, Tole and Independencehttps://digitalcommons.ursinus.edu/pafolklifemag/1069/thumbnail.jp

Distribution of metals exposure and associations with cardiometabolic risk factors in the “Modeling the Epidemiologic Transition Study”

Background: Metals are known endocrine disruptors and have been linked to cardiometabolic diseases via multiple potential mechanisms, yet few human studies have both the exposure variability and biologically-relevant phenotype data available. We sought to examine the distribution of metals exposure and potential associations with cardiometabolic risk factors in the “Modeling the Epidemiologic Transition Study” (METS), a prospective cohort study designed to assess energy balance and change in body weight, diabetes and cardiovascular disease risk in five countries at different stages of social and economic development. Methods: Young adults (25–45 years) of African descent were enrolled (N = 500 from each site) in: Ghana, South Africa, Seychelles, Jamaica and the U.S.A. We randomly selected 150 blood samples (N = 30 from each site) to determine concentrations of selected metals (arsenic, cadmium, lead, mercury) in a subset of participants at baseline and to examine associations with cardiometabolic risk factors. Results: Median (interquartile range) metal concentrations (μg/L) were: arsenic 8.5 (7.7); cadmium 0.01 (0.8); lead 16.6 (16.1); and mercury 1.5 (5.0). There were significant differences in metals concentrations by: site location, paid employment status, education, marital status, smoking, alcohol use, and fish intake. After adjusting for these covariates plus age and sex, arsenic (OR 4.1, 95% C.I. 1.2, 14.6) and lead (OR 4.0, 95% C.I. 1.6, 9.6) above the median values were significantly associated with elevated fasting glucose. These associations increased when models were further adjusted for percent body fat: arsenic (OR 5.6, 95% C.I. 1.5, 21.2) and lead (OR 5.0, 95% C.I. 2.0, 12.7). Cadmium and mercury were also related with increased odds of elevated fasting glucose, but the associations were not statistically significant. Arsenic was significantly associated with increased odds of low HDL cholesterol both with (OR 8.0, 95% C.I. 1.8, 35.0) and without (OR 5.9, 95% C.I. 1.5, 23.1) adjustment for percent body fat. Conclusions: While not consistent for all cardiometabolic disease markers, these results are suggestive of potentially important associations between metals exposure and cardiometabolic risk. Future studies will examine these associations in the larger cohort over time

Common variants in FOXP1 are associated with generalized vitiligo

In a recent genome-wide association study of generalized vitiligo, we identified ten confirmed susceptibility loci. By testing additional loci that showed suggestive association in the genome-wide study, using two replication cohorts of European descent, we observed replicated association of generalized vitiligo with variants at 3p13 encompassing FOXP1 (rs17008723, combined P = 1.04 × 10−8) and with variants at 6q27 encompassing CCR6 (rs6902119, combined P = 3.94 × 10−7)