GERMS JOURNEY: co-creation of resources for addressing UN Sustainable Development Goals in education & health in developing countries

Following a Participatory Action Research (PAR) model, this study evaluates whether specifically developed resources (‘A Germ’s Journey’) aid children in India’s understanding of hand-hygiene principles. Furthermore, it discusses how the findings can inform the future development of culturally relevant resources for developing countries. Educational health-hygiene workshops were conducted with schools and community centres in collaboration with organisations in Ahmedabad, India in areas of considerable socio-economic disadvantage. Children’s and teacher-trainer workshops were delivered to ten Case Studies. Mixed-method data was collected from children using quasi-experimental methods, using pre-workshop questions, follow-up questions, observations and baseline and post-workshop assessments. Data was collected from teachers using questionnaires. Following teacher-trainer workshops during Phase 1 of the study, 100% of teachers stated that they would use the resources with their pupils in the future. Two months after participating in the workshops, 60-73% of children knew how germs can cause illness, and 76-80% knew how to remove germs from hands. When assessed during Phase 2 of the study, 55% of children scored higher after the intervention, showing an increased understanding of microbiology after using the resources. The results indicate that children have an improved understanding of the cause of bacterial disease and the health implications of not using adequate health-hygiene practices. Recommendations for the future development of resources include adopting a PAR model of research, co-creation with end users and working alongside local organisations and participants in order to access the ‘hard-to-reach’ areas

Multiparty computations in varying contexts

Recent developments in the automatic transformation of protocols into Secure Multiparty Computation (SMC) interactions, and the selection of appropriate schemes for their implementation have improved usabililty of SMC. Poor performance along with data leakage or errors caused by coding mistakes and complexity had hindered SMC usability. Previous practice involved integrating the SMC code into the application being designed, and this tight integration meant the code was not reusable without modification. The progress that has been made to date towards the selection of different schemes focuses solely on the two-party paradigm in a static set-up, and does not consider changing contexts. Contexts, for secure multiparty computation, include the number of participants, link latency, trust and security requirements such as broadcast, dishonest majority etc. Variable Interpretation is a concept we propose whereby specific domain constructs, such as multiparty computation descriptions, are explicitly removed from the application code and expressed in SMC domain representation. This mirrors current practice in presenting a language or API to hide SMC complexity, but extends it by allowing the interpretation of the SMC to be adapted to the context. It also decouples SMC from human co-ordination by introducing a rule-based dynamic negotiation of protocols. Experiments were carried out to validate the method, running a multiparty computation on a variable interpreter for SMC using different protocols in different contexts

Biocultural Diversity and Conservation around Mt Cameroon: Traditional knowledge, management and governance in the era of sustainable development

This thesis explores different facets of the interface of traditional management systems around Mt Cameroon and national and global conservation policy and practice, including the way in which traditional management systems and 'non-timber forest products' have come to be studied and understood in the context of human-environment interactions and as a way of attempting to align economic development and conservation goals. Mt Cameroon has long been characterized by change and transformation - cultural, economic, ecological, political - all of which contribute to its extraordinary biological and cultural diversity. A global hotspot for biodiversity, in recent decades Mt Cameroon has attracted the attention of numerous conservation programs and donors. My research uses a range of intersecting questions, methods and approaches to capture the dynamics of social and environmental change at multiple scales, and over decades. It explores the way in which local-level knowledge and practices are shaped and mediated between households, communities, local and global markets and extra-local forces and agents, in particular those linked to livelihood and market-based conservation initiatives. I argue that a failure to identify the social and environmental dynamics of local groups' forest management practices, and an incongruously large emphasis on products sold in markets, can often legitimize the extractive activities that cause biodiversity and forest loss in the first place, while de-emphasizing locally-driven change and - ironically - glossing over diversity in cultures and ecosystems in pursuit of uniform, global prescriptions

Confirmed presence of the squash bee, Peponapis pruinosa (Say, 1837) in the state of Oregon and specimen-based observational records of Peponapis (Say, 1837) (Hymenoptera: Anthophila) in the Oregon State Arthropod Collection

A new Oregon record for Peponapis pruinosa (Say, 1837) is presented with notes on its occurrence and photographs. This record provides the first empirical evidence of the genus and species in the state of Oregon. A dataset of Peponapis (Say, 1837) specimens in the holdings of the Oregon State Arthropod Collection is included with a brief summary of its contents

Dynamical Processes in the Planet-Forming Environment

The transfer of circumstellar disk mass and momentum onto the protostar and out into the environment occurs via a variety of mechanisms including magnetospheric accretion, jets, outflows, and disk winds. The interplay of these processes determine both the conditions under which planet formation occurs and the lifetime of the disk. Metallic emission lines, along with the Balmer series of hydrogen, probe the kinematics of gas within the planet-forming and central regions of circumstellar disks. High-spectral resolution study of these emission lines provides critical information on mass and momentum loss, turbulence, and disk wind origins

Farmers’ Rights and Digital Sequence Information: Crisis or Opportunity to Reclaim Stewardship Over Agrobiodiversity?

Contestations about the way in which digital sequence information is used and regulated have created stumbling blocks across multiple international policy processes. Such schisms have profound implications for the way in which we manage and conceptualize agrobiodiversity and its benefits. This paper explores the relationship between farmers’ rights, as recognized in the International Treaty on Plant Genetic Resources for Food and Agriculture, and the dematerialization of genetic resources. Using concepts of “stewardship” and “ownership” we emphasize the need to move away from viewing agrobiodiversity as a commodity that can be owned, toward a strengthened, proactive and expansive stewardship approach that recognizes plant genetic resources for food and agriculture as a public good which should be governed as such. Through this lens we analyze the relationship between digital sequence information and different elements of farmers’ rights to compare and contrast implications for the governance of digital sequence information. Two possible parallel pathways are presented, the first envisaging an enhanced multilateral system that includes digital sequence information and which promotes and enhances the realization of farmers’ rights; and the second a more radical approach that folds together concepts of stewardship, farmers’ rights, and open source science. Farmers’ rights, we suggest, may well be the linchpin for finding fair and equitable solutions for digital sequence information beyond the bilateral and transactional approach that has come to characterize access and benefit sharing under the Convention on Biological Diversity. Existing policy uncertainties could be seized as an unexpected but serendipitous opportunity to chart an alternative and visionary pathway for the rights of farmers and other custodians of plant genetic resources.publishedVersio

A longitudinal and comparative content analysis of Instagram fitness posts

Body dissatisfaction is among the most common mental health challenges experienced by women and has been identified as a risk factor for disordered eating. Research has found that exposure to social media images depicting thin, muscular bodies, often dubbed ‘fitspiration’, may contribute to body dissatisfaction. Image-centred social media platforms, such as Instagram, have rising popularity among adolescents and young adults. However, little is known about the content of images produced by different fitness-related sources, such as those from fitness brands compared with individual users, and how fitness content on social media is evolving over time. This study sought to determine whether Instagram content varied between female fitness influencers and brands and how this content changed between 2019 and 2021. A longitudinal content analysis was conducted on a sample of 400 Instagram images using a coding scheme developed specifically for this project. The scheme coded images for fit ideal body depiction, fitness focus, objectification, and sexualisation. Chi-square tests indicated that female fitness influencer content was more sexualised and portrayed more of the fit ideal, while fitness brands produced more Instagram content with a fitness focus. There were no significant overall longitudinal changes for any of the four key variables. However, when looking at longitudinal changes by account type, fitness-focused influencer content increased while fitness-focused brand content decreased over time. These findings highlight discernible differences in content produced by different Instagram account types. It points future research towards the consideration of potential moderating factors, such as account type, when exploring the impact of social media images on body image and mental health

Improving image analysis in 2DGE-based redox proteomics by labeling protein carbonyl with fluorescent hydroxylamine

Recent advances in redox proteomics have provided significant insight into the role of oxidative modifications in cellular signalling and metabolism. At present, these techniques rely heavily on Western blots to visualize the oxidative modification and corresponding two dimensional (2D) gels for detection of total protein levels, resulting in the duplication of efforts. A major limitation associated with this methodology includes problematic matching up of gels and blots due to the differences in processing and/or image acquisition. In this study, we present a new method which allows detection of protein oxidation and total protein on the same gel to improve matching in image analysis. Furthermore, the digested protein spots are compatible with standard MALDI mass spectrometry protein identification. The methodology highlighted here may be useful in facilitating the development of biomarkers, assessing potential therapeutic targets and elucidating new mechanisms of redox signalling in redox-related conditions

Serum relaxin levels are reduced in pregnant women with a history of recurrent miscarriage, and correlate with maternal uterine artery Doppler indices in first trimester

Objectives: Defective implantation is a mechanism for recurrent pregnancy loss (RPL). We sought to determine whether the serum expression of human relaxin-2 (RLX) is impaired in women with a history of RPL. Study design: Employing a prospective case-controlled design we studied 20 pregnant women with a history of RPL and 20 age-matched women with no history of RPL (NRPL). We measured serum relaxin-2 levels by ELISA at 6-8. 10-12, 20, and 34 weeks gestation and in cord blood, and maternal uterine artery Doppler resistance index (RI) at >= 10 weeks gestation. Results: Relaxin rose to a peak at 12 weeks, and gradually declined towards term. At all gestations, women with a history of RPL had lower RLX levels than women without. At 10-12 weeks gestation, uterine artery RI correlated with serum RLX for both RPL and NRPL. In the NRPL group at 10-12 weeks the presence of a notched waveform was associated with higher RLX levels than the absence of a notch (mean 2.1 ng/ml vs. 1.3 ng/ml, P < 0.05) and also at 20 weeks (2.1 ng/ml vs. 0.95 ng/ml, P < 0.05) but no such difference was seen in the RPL group. Umbilical venous RLX was 4-fold higher in the RPL group than the NRPL group. Conclusion: Women with a history of RPL demonstrate attenuated levels of serum RLX across all pregnancy trimesters. How dysregulated RLX metabolism may contribute to adverse pregnancy outcome in RPL requires further investigation. Crown Copyright (C) 2009 Published by Elsevier Ireland Ltd. All rights reserved