Urbanization and Carpobrotus edulis invasion alter the diversity and composition of soil bacterial communities in coastal areas

Coastal dunes are ecosystems of high conservation value that are strongly impacted by human disturbances and biological invasions in many parts of the world. Here we assessed how urbanization and Carpobrotus edulis invasion affect soil bacterial communities on the north-western coast of Spain, by comparing the diversity, structure and composition of soil bacterial communities in invaded and uninvaded soils from urban and natural coastal dune areas. Our results suggest that coastal dune bacterial communities contain large numbers of rare taxa, mainly belonging to the phyla Actinobacteria and Proteobacteria. We found that the presence of the invasive C. edulis increased the diversity of soil bacteria andchanged community composition, while urbanization only influenced bacterial community composition. Furthermore, the effects of invasion on community composition were conditional on urbanization. These results were contrary to predictions, as both C. edulis invasion and urbanization have been shown to affect soil abiotic conditions of the studied coastal dunes in a similar manner, and therefore were expected to have similar effects on soil bacterial communities. Our results suggest that other factors (e.g. pollution) might be influencing the impact of urbanization on soil bacterial communities, preventing an increase in the diversity of soil bacteria in urban areas

Towards the elsewhere : Discourses on migration and mobility practices between Morocco and Italy.

peer reviewedThe objective of this article is to analyze the preparation process of young Moroccan migrants directed towards Italy. My focus is on the personal and collective formulation of their desire to leave and on concomitant action taken to realize these aspirations; highlighting the complexity of the imagination, which migration – and expected return – entails. A second point of attention is the agency exerted by such youth during preparation for departure; even when they have not physically left the country yet. In addition, my observation is focussed on networks emerging as a result of having to deal with state-imposed, migration restrictions, as well as with the politics of humanitarian agencies and NGOs. My discourse argues that these aspiring migrants project themselves into the future and act in accordance with what they long to become. They shape themselves as mobile subjects through a process of self-making to overcome the above-mentioned constraints

Surplus production, variability, and climate change in the great sardine and anchovy fisheries

We used fishery and survey data to calculate annual surplus production (ASP) and instantaneous surplus production rates (ISPR) for eight anchovy and nine sardine stocks. In addition, we calculated ASP per unit spawning area for six anchovy and six sardine stocks. Median ASP was highest for stocks with highest median biomass (mostly anchovies), and ASP was typically about 16% of stock biomass. ASP was often negative, more frequently for anchovies (36% of years) than for sardines (17% of years). ISPR was less variable for sardines and autocorrelated for longer-lived stocks (mostly sardines). Strong biomass increases tended to be preceded by short, abrupt increases in ISPR, and declines were pronounced when catches exceeded ASP for 5 years or more. The longest “runs” of positive and negative production were 21 and 4 years for sardine off Japan, 10 and 3 years for sardine off California, 8 and 2 years for anchovy off Peru, and 4 and 3 years for anchovy off California. ISPR is more sensitive to environmental changes than catch, biomass, or ASP and appear to be better for identifying environmentally induced regime shifts. Long time series show evidence of density-dependent effects on ASP in anchovies and sardines, but environmentally induced variation appears to dominate.Des statistiques de pêche et des données d’inventaire nous ont servi à calculer la production excédentaire annuelle (ASP) et les taux instantanés de production excédentaire (ISPR) chez huit stocks d’anchois et neuf stocks de sardines. De plus, nous avons calculé l’ASP par unité de surface de frayère chez six stocks d’anchois et six stocks de sardines. L’ASP moyen est maximal chez les stocks qui possèdent la plus grande biomasse médiane (surtout des anchois) et correspond normalement à environ 16% de la biomasse du stock. L’ASP est souvent négative, plus souvent chez les anchois (36% des années) que chez les sardines (17% des années). L’ISPR est moins variable chez les sardines et est autocorrelé chez les stocks à longévité plus grande (surtout des sardines). Les augmentations importantes de biomasse sont normalement précédées d’une croissance abrupte de l’ISPR; lorsque les prises dépassent l’ASP pour 5 ans ou plus, il y a un déclin prononcé. Les plus longues « séquences » de production positive et négative ont été respectivement de 21 et 4 années pour les sardines au large du Japon, de 10 et 3 années pour les sardines au large de la Californie, de 8 et 2 années pour les anchois au large du Pérou et de 4 et 3 années pour les anchois au large de la Californie. Les ISPR est plus sensible aux changements de l’environnement que ne le sont les captures, la biomasse ou l’ASP et semblent être plus appropriés pour détecter les changements de régime dus à l’environnement. Les longues séries temporelles laissent croire à l’existence d’effets de densité-dépendance sur l’ASP chez les anchois et les sardines, mais la variation attribuable à l’environnement semble dominer.Versión del editor2,213

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages.

Dysregulated adipocyte physiology leads to imbalanced energy storage, obesity, and associated diseases, imposing a costly burden on current health care. Cannabinoid receptor type-1 (CB1) plays a crucial role in controlling energy metabolism through central and peripheral mechanisms. In this work, adipocyte-specific inducible deletion of the CB1 gene (Ati-CB1- KO) was sufficient to protect adult mice from diet-induced obesity and associated metabolic alterations and to reverse the phenotype in already obese mice. Compared with controls, Ati-CB1-KO mice showed decreased body weight, reduced total adiposity, improved insulin sensitivity, enhanced energy expenditure, and fat depot-specific cellular remodeling toward lowered energy storage capacity and browning of white adipocytes. These changes were associated with an increase in alternatively activated macrophages concomitant with enhanced sympathetic tone in adipose tissue. Remarkably, these alterations preceded the appearance of differences in body weight, highlighting the causal relation between the loss of CB1 and the triggering of metabolic reprogramming in adipose tissues. Finally, the lean phenotype of Ati-CB1-KO mice and the increase in alternatively activated macrophages in adipose tissue were also present at thermoneutral conditions. Our data provide compelling evidence for a crosstalk among adipocytes, immune cells, and the sympathetic nervous system (SNS), wherein CB1 plays a key regulatory role

O fenômeno El Niño Oscilação Sul e a variabilidade interanual da evaporação do tanque Classe A e da umidade relativa do ar em Santa Maria, RS El Niño Southern Oscilation and the interannual variability of Pan evaporation and air relative humidity in Santa Maria, RS, Brazil

O objetivo deste trabalho foi associar a variabilidade interanual da evaporação do tanque Classe A e da umidade relativa do ar com o fenômeno El Niño Oscilação Sul (ENOS) em Santa Maria, RS. Foram utilizados os dados diários de evaporação do tanque Classe A (ECA, mm dia-1) e umidade relativa média diária do ar (UR, %) medidos em Santa Maria, RS. A ECA foi medida de 1973 a 2006 e a UR de 1969 a 2006. Os anos foram classificados em El Niño (EN), La Niña (LN) e Neutros (N), considerando o período de 01/07 de um ano até 30/06 do ano seguinte. Os resultados mostraram que a ECA é menor nos anos de EN e maior nos anos de LN. Já a UR foi maior em anos de EN e menor em anos de LN. O efeito do fenômeno ENOS sobre a ECA é maior nos meses de novembro, dezembro, janeiro e maio, enquanto que sobre a UR os meses de maior influência do ENOS são outubro, novembro, dezembro e maio.<br>The objective of this study was to associate the interannual variability of Pan evaporation and air relative humidity with the El Niño Southern Oscilation (ENSO) phenomenon in Santa Maria, RS, Brazil. Daily data records of Pan evaporation (PAN, mm day-1) and mean daily relative humidity (RH, %) measured in Santa Maria, RS, were used. PAN was measured from 1973 to 2006 and RH was measured from 1969 to 2006. Years were grouped into El Niño (EN) years, La Niña (LN) years, and Neutral (N) years, from July 1st of the year to June 30th of the following year. Results showed that PAN is lower in EN years and greater in LN years. On the other hand, RH was greater in EN years and lower in LN years. The effect of ENSO on PAN is greater in November, December, January, and May, whereas RH is affected by ENSO in October, November, December and May

Pharmacologic management of patients with both heart failure and diabetes

Diabetes and heart failure often occur together in patients, with each condition influencing the treatment of the other. Each disease has its own well-documented impact on prognosis, but when they are present in the same patient, the risk of morbidity and mortality increases substantially. Some therapies used in the treatment of diabetes are contraindicated in patients with heart failure, and some therapies for treating heart failure are often mistakenly believed to be contraindicated in patients with diabetes. This article aims to clarify the evidence behind treating these conditions simultaneously and dispel the myths surrounding the pharmacologic management of diabetes in heart failure and vice vers