23,999 research outputs found
Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen.
IL-2 potentiates both growth and cytotoxic function of T lymphocytes and NK cells. Resting peripheral blood NK cells can respond directly to rIL-2, without requirement for accessory cells or cofactors, and enhanced cytotoxicity can be measured within a few hours after exposure to this lymphokine. In this study, we describe an activation antigen, Leu-23, that is rapidly induced and phosphorylated after IL-2 stimulation of NK cells and a subset of low buoyant density T lymphocytes. Previously, it has been uncertain whether all NK cells or only a subset are responsive to IL-2. Since within 18 h after exposure to IL-2, essentially all NK cells express Leu-23, these findings indicate that all peripheral blood NK cells are responsive to stimulation by IL-2. The Leu-23 antigen is a disulfide-bonded homodimer, composed of 24-kD protein subunits with two N-linked oligosaccharides. Appearance of this glycoprotein on NK cells is IL-2 dependent and closely parallels IL-2-induced cytotoxicity against NK-resistant solid tumor cell targets
Secrecy content of two-qubit states
We analyze the set of two-qubit states from which a secret key can be
extracted by single-copy measurements plus classical processing of the
outcomes. We introduce a key distillation protocol and give the corresponding
necessary and sufficient condition for positive key extraction. Our results
imply that the critical error rate derived by Chau, Phys. Rev. A {\bf 66},
060302 (2002), for a secure key distribution using the six-state scheme is
tight. Remarkably, an optimal eavesdropping attack against this protocol does
not require any coherent quantum operation.Comment: 5 pages, RevTe
Reconfiguring experimental archaeology using 3D reconstruction
Experimental archaeology has long yielded valuable insights into the tools and techniques that featured in past peoples’ relationship with the material world around them. We can determine, for example, how many trees would need to be felled to construct a large round-house of the southern British Iron Age (over one hundred), infer the exact angle needed to strike a flint core in order to knap an arrowhead in the manner of a Neolithic hunter-gatherer, or recreate the precise environmental conditions needed to store grain in underground silos over the winter months, with only the technologies and materials available to Romano-Briton villagers (see Coles 1973; Reynolds 1993). However, experimental archaeology has, hitherto, confined itself to rather rigid, empirical and quantitative questions such as those posed in these examples. This is quite understandable, and in line with good scientific practice, which stipulates that any ‘experiment’ must be based on replicable data, and be reproducible. Despite their potential in this area however, it is notable that digital reconstruction technologies have yet to play a significant role in experimental archaeology. Whilst many excellent examples of digital 3D reconstruction of heritage sites exist (for example the Digital Roman Forum project: http://dlib.etc.ucla.edu/projects/Forum) most, if not all, of these are characterized by a drive to establish a photorealistic re-creation of physical features. This paper will discuss possibilities that lie beyond straightforward positivist re-creation of heritage sites, in the experimental reconstruction of intangible heritage. Between 2010 and 2012, the authors led the Motion in Place Platform project (MiPP: http://www.motioninplace.org/), a capital grant under the AHRC's DEDEFI scheme developing motion capture and analysis tools for exploring how people move through spaces. In the course of MiPP, a series of experiments were conducted using motion capture hardware and software at the Silchester Roman town archaeological excavation in Hampshire, and at the Butser Ancient Farm facility, where Romano-British and Iron Age dwellings have been constructed according to the best experimental practice. As well as reconstructing such Roman and early British dwellings in 3D, the authors were able to use motion capture to reconstruct the kind of activities that – according to the material evidence – are likely to have been carried out by the occupants who used them. Bespoke motion capture suits developed for the project were employed, and the traces captured and rendered with a combination of Autodesk and Unity3D software. This sheds new light on how the reconstructed spaces - and, by inference, their ancient counterparts - were most likely to have been used. In particular the exercises allowed the evaluation and visualisation of changes in behaviour which occur as a result of familiarity with an environment and the acquisition of expertise over time; and to assess how interaction between different actors affects how everyday tasks are carried out
Far-infrared edge modes in quantum dots
We have investigated edge modes of different multipolarity sustained by
quantum dots submitted to external magnetic fields. We present a microscopic
description based on a variational solution of the equation of motion for any
axially symmetric confining potential and multipole mode. Numerical results for
dots with different number of electrons whose ground-state is described within
a local Current Density Functional Theory are discussed. Two sum rules, which
are exact within this theory, are derived. In the limit of a large neutral dot
at B=0, we have shown that the classical hydrodynamic dispersion law for edge
waves \omega(q) \sim \sqrt{q \ln (q_0/q)} holds when quantum and finite size
effects are taken into account.Comment: We have changed some figures as well as a part of the tex
Far-infrared edge modes in quantum dots
We have investigated edge modes of different multipolarity sustained by
quantum dots submitted to external magnetic fields. We present a microscopic
description based on a variational solution of the equation of motion for any
axially symmetric confining potential and multipole mode. Numerical results for
dots with different number of electrons whose ground-state is described within
a local Current Density Functional Theory are discussed. Two sum rules, which
are exact within this theory, are derived. In the limit of a large neutral dot
at B=0, we have shown that the classical hydrodynamic dispersion law for edge
waves \omega(q) \sim \sqrt{q \ln (q_0/q)} holds when quantum and finite size
effects are taken into account.Comment: We have changed some figures as well as a part of the tex
Orbital current mode in elliptical quantum dots
An orbital current mode peculiar to deformed quantum dots is theoretically
investigated; first by using a simple model that allows to interpret
analytically its main characteristics, and second, by numerically solving the
microscopic equations of time evolution after an initial perturbation within
the time-dependent local-spin-density approximation. Results for different
deformations and sizes are shown.Comment: 4 REVTEX pages, 4 PDF figures, accepted in PRB:R
Scissors modes in triaxial metal clusters
We study the scissors mode (orbital M1 excitations) in small Na clusters,
triaxial metal clusters and and the
close-to-spherical , all described in DFT with detailed ionic
background. The scissors modes built on spin-saturated ground and
spin-polarized isomeric states are analyzed in virtue of both macroscopic
collective and microscopic shell-model treatments. It is shown that the mutual
destruction of Coulomb and the exchange-correlation parts of the residual
interaction makes the collective shift small and the net effect can depend on
details of the actual excited state. The crosstalk with dipole and spin-dipole
modes is studied in detail. In particular, a strong crosstalk with spin-dipole
negative-parity mode is found in the case of spin-polarized states. Triaxiality
and ionic structure considerably complicate the scissors response, mainly at
expense of stronger fragmentation of the strength. Nevertheless, even in these
complicated cases the scissors mode is mainly determined by the global
deformation. The detailed ionic structure destroys the spherical symmetry and
can cause finite M1 response (transverse optical mode) even in clusters with
zero global deformation. But its strength turns out to be much smaller than for
the genuine scissors modes in deformed systems.Comment: 17 pages, 5 figure
Multiple copy 2-state discrimination with individual measurements
We address the problem of non-orthogonal two-state discrimination when
multiple copies of the unknown state are available. We give the optimal
strategy when only fixed individual measurements are allowed and show that its
error probability saturates the collective (lower) bound asymptotically. We
also give the optimal strategy when adaptivity of individual von Neumann
measurements is allowed (which requires classical communication), and show that
the corresponding error probability is exactly equal to the collective one for
any number of copies. We show that this strategy can be regarded as Bayesian
updating.Comment: 5 pages, RevTe
Rotating Hele-Shaw cells with ferrofluids
We investigate the flow of two immiscible, viscous fluids in a rotating
Hele-Shaw cell, when one of the fluids is a ferrofluid and an external magnetic
field is applied. The interplay between centrifugal and magnetic forces in
determining the instability of the fluid-fluid interface is analyzed. The
linear stability analysis of the problem shows that a non-uniform, azimuthal
magnetic field, applied tangential to the cell, tends to stabilize the
interface. We verify that maximum growth rate selection of initial patterns is
influenced by the applied field, which tends to decrease the number of
interface ripples. We contrast these results with the situation in which a
uniform magnetic field is applied normally to the plane defined by the rotating
Hele-Shaw cell.Comment: 12 pages, 3 ps figures, RevTe
Magnetoplasmons in quantum rings
We have studied the structure and dipole charge density response of nanorings
as a function of the magnetic field using local-spin density functional theory.
Two small rings consisting of 12 and 22 electrons confined by a positively
charged background are used to represent the cases of a narrow and a wide ring.
The results are qualitatively compared with experimental data existing on
microrings and on antidots. A smaller ring containing 5 electrons is also
analyzed to allow for a closer comparison with a recent experiment on a two
electron quantum ring.Comment: Typeset using Revtex, 13 pages and 11 Postscript figure
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