Modifying the Mineral Profile of Crickets (\u3ci\u3eAcheta domesticus\u3c/i\u3e) Using a Supplemented Diet

Captive insectivores may consume invertebrates as all, or part of their overall diet. The challenge with feeding captive insectivores involves the limited number of invertebrate species that are commercially available, and the lack of key nutrients provided by these insects. Among these insects, a naturally occurring low concentration of calcium and an inverse calcium to phosphorus ratio may put insectivores at the risk of developing hypocalcemia. A strategy to correct this nutrient imbalance involves supplementing the insect diet with high concentrations of targeted nutrients – a term referred to as gut-loading. Current industry guidelines recommend feeding a supplemented diet for 48 to 72 h before offering the insect to an insectivore. In the present study, the mineral profile of adult crickets (Acheta domesticus) offered a maintenance diet (1.58% Ca, DMB) are compared to crickets offered a supplemented diet (11.32% Ca, DMB) over 120 h. The supplemented diet produced a cricket with significantly higher calcium concentration compared to the maintenance diet. The calcium concentration of crickets offered the supplemented diet was highest at 48 h (0.63%), but did not achieve a 1:1 Ca:P ratio nor meet the lowest reported nutrient requirements of carnivorous reptiles, omnivorous reptiles, or an insectivorous bird at various life stages. Although the supplemented diet improved the whole body calcium concentration in feeder crickets, the crickets do not provide adequate calcium, iron, or manganese to meet the requirement of insectivores. As evidenced by the current study, the supplemented crickets are not recommended to serve as the sole source of nutrition for an insectivore

Lorentz-violating contributions of the Carroll-Field-Jackiw model to the CMB anisotropy

We study the finite temperature properties of the Maxwell-Carroll-Field-Jackiw (MCFJ) electrodynamics for a purely spacelike background. Starting from the associated finite temperature partition function, a modified black body spectral distribution is obtained. We thus show that, if the CMB radiation is described by this model, the spectrum presents an anisotropic angular energy density distribution. We show, at leading order, that the Lorentz-breaking contributions for the Planck's radiation law and for the Stefan-Boltzmann's law are nonlinear in frequency and quadratic in temperature, respectively. Using our results, we set up bounds for the Lorentz-breaking parameter, and show that Lorentz violation in the context of the MCFJ model is unable to yield the known CMB anisotropy (of 1 part in $10^{5})$

A Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8, Bound to DNA Gyrase

Simocyclinones are bifunctional antibiotics that inhibit bacterial DNA gyrase by preventing DNA binding to the enzyme. We report the crystal structure of the complex formed between the N-terminal domain of the Escherichia coli gyrase A subunit and simocyclinone D8, revealing two binding pockets that separately accommodate the aminocoumarin and polyketide moieties of the antibiotic. These are close to, but distinct from, the quinolone-binding site, consistent with our observations that several mutations in this region confer resistance to both agents. Biochemical studies show that the individual moieties of simocyclinone D8 are comparatively weak inhibitors of gyrase relative to the parent compound, but their combination generates a more potent inhibitor. Our results should facilitate the design of drug molecules that target these unexploited binding pockets

Go-green manufacturing holons: a step towards sustainable manufacturing operations control

Despite their potential benefits in the context of sustainable manufacturing operations, holonic and multi-agent architectures are still not designed methodologically to support this major societal and environmental stake. To fill the gap, the generic concept of go-green manufacturing holon is proposed. The idea is to incite researchers to develop sustainability-oriented manufacturing operations control architectures, being holonic or multi-agents, and to provide them with a usable generic concept easy to appropriate, particularize and implement. An illustration of the concept is proposed as well as its widening in the context of circular economy.Trentesaux, D.; Giret Boggino, AS. (2015). Go-green manufacturing holons: a step towards sustainable manufacturing operations control. Manufacturing letters. 5:29-33. doi:10.1016/j.mfglet.2015.07.003S2933

Paragraph-level Commonsense Transformers with Recurrent Memory

Human understanding of narrative texts requires making commonsense inferences beyond what is stated explicitly in the text. A recent model, COMET, can generate such implicit commonsense inferences along several dimensions such as pre- and post-conditions, motivations, and mental states of the participants. However, COMET was trained on commonsense inferences of short phrases, and is therefore discourse-agnostic. When presented with each sentence of a multi-sentence narrative, it might generate inferences that are inconsistent with the rest of the narrative. We present the task of discourse-aware commonsense inference. Given a sentence within a narrative, the goal is to generate commonsense inferences along predefined dimensions, while maintaining coherence with the rest of the narrative. Such large-scale paragraph-level annotation is hard to get and costly, so we use available sentence-level annotations to efficiently and automatically construct a distantly supervised corpus. Using this corpus, we train PARA-COMET, a discourse-aware model that incorporates paragraph-level information to generate coherent commonsense inferences from narratives. PARA-COMET captures both semantic knowledge pertaining to prior world knowledge, and episodic knowledge involving how current events relate to prior and future events in a narrative. Our results show that PARA-COMET outperforms the sentence-level baselines, particularly in generating inferences that are both coherent and novel.Comment: AAAI 202

Venture studioer og serieentreprenører: En eksplorativ sammenligning av entreprenørielle strategier

Serieentreprenører er viktige bidragsytere i entreprenørielle økosystemer (Ensign & Farlow, 2016). Forskning viser at serieentreprenørene starter flere bedrifter enn førstegangsentreprenører, samtidig opplever bedriftene deres på generell basis høyere avkastning enn bedrifter startet av førstegangsentreprenører (Shaw & Sørensen, 2019). I nyere tid har en ny modell entret det entreprenørielle økosystemet som spesialiserer seg på å starte og skalere nye foretak (Muñoz Abreu, 2021). Venture studio modellen opplever høy anseelse og tiltrekker seg stadig mer oppmerksomhet i bransjen (Patel & Chan, 2023). Vår studie søker å sammenligne serieentreprenører og venture studioer, ikke for å finne ut hvem som er mest lønnsomme, men for å finne ut hvordan de skiller seg fra hverandre. Vår artikkel presenterer funn som impliserer at venture studioet er å anse som en maskin for entreprenøriell læring. Vi antyder også at venture studioer har betydelige evner når det kommer til å tiltrekke seg funksjonelt mangfoldige team som er bevist å øke en virksomhets prestasjon (Kirschenhofer & Lechner, 2012).Serial entrepreneurs are important contributors in entrepreneurial ecosystems (Ensign & Farlow, 2016). Research shows that serial entrepreneurs start more businesses than first-time entrepreneurs, and their businesses generally experience higher returns than those started by first-time entrepreneurs (Shaw & Sørensen, 2019). Recently, a new model has entered the entrepreneurial ecosystem that specializes in starting and scaling new ventures (Muñoz Abreu, 2021). The venture studio model is highly regarded and is attracting increasing attention in the industry (Patel & Chan, 2023). Our study seeks to compare serial entrepreneurs and venture studios, not to determine which is more profitable, but to explore how they differ from each other. Our article presents findings that suggest the venture studio is a machine for entrepreneurial learning. We also suggest that venture studios have significant abilities in attracting functionally diverse teams that have been proven to enhance a firm's performance (Kirschenhofer & Lechner, 2012)

RS-invariant all-orders renormalon resummations for some QCD observables

We propose a renormalon-inspired resummation of QCD perturbation theory based on approximating the renormalization scheme (RS) invariant effective charge beta-function coefficients by the portion containing the highest power of $b$=$\frac{1}{6}(11N$--$2N_{f})$, for SU($N$) QCD with $N_{f}$ quark flavours. This can be accomplished using exact large-$N_{f}$ all-orders results. The resulting resummation is RS-invariant and the exact next-to-leading order (NLO) and next-to-NLO (NNLO) coefficients in any RS are included. This improves on a previously employed naive resummation of the leading-$b$ piece of the perturbative coefficients which is RS-dependent, making its comparison with fixed-order perturbative results ambiguous. The RS-invariant resummation is used to assess the reliability of fixed-order perturbation theory for the $e^{+}e^{-}$ $R$-ratio, the analogous $\tau$-lepton decay ratio $R_{\tau}$, and Deep Inelastic Scattering (DIS) sum rules, by comparing it with the exact NNLO results in the effective charge RS. For the $R$-ratio and $R_{\tau}$, where large-order perturbative behaviour is dominated by a leading ultra-violet renormalon singularity, the comparison indicates fixed-order perturbation theory to be very reliable. For DIS sum rules, which have a leading infra-red renormalon singularity, the performance is rather poor. In this way we estimate that at LEP/SLD energies ideal data on the $R$-ratio could determine $\alpha_{s}(M_{Z})$ to three-significant figures, and for the $R_{\tau}$ we estimate a theoretical uncertainty $\delta\alpha_{s}(m_{\tau})\simeq0.008$ corresponding to $\delta\alpha_{s}(M_{Z})\simeq0.001$. This encouragingly small uncertainty is much less than has recently been deduced from comparison with the ambiguous naive resummation.Comment: 25 pages, uses LaTeX, 12 Postscript figures, epsfig.sty 'elsart.sty' and 'elsart12.sty' are available via anonymous-ftp at ftp://ftp.tex.ac.uk/tex-archive/macros/latex/contrib/supported/elsevie

Renormalon-inspired resummations for vector and scalar correlators- estimating the uncertainty in {alpha}_{s}({m}_{\tau}^{2}) and and {\alpha}({M}_{Z}^{2})

We perform an all-orders resummation of the QCD Adler D-function for the vector correlator, in which the portion of perturbative coefficients involving the leading power of b, the first beta-function coefficient, is resummed. To avoid a renormalization scale dependence when we match the resummation to the exactly known NLO and NNLO results, we employ the Complete Renormalization Group Improvement (CORGI) approach. These fixed-order and resummed CORGI results are analytically continued by numerically performing a contour integral to obtain corresponding fixed and all-orders ``contour-improved'' results for the e+e- R-ratio ands its tau decay analogue R_{\tau}. The difference between these fixed-order and all-order results is used to estimate the uncertainty in the extraction of {alpha}_{s}({M}_{Z}^{2}} from R_{\tau} measurements, and that in the QED coupling {\alpha}({M}_{Z}^{2}) due to hadronic corrections related to R. Analogous resummations for the scalar correlator are performed, and used to assess the uncertainty in the Higgs decay width to a heavy quark pair. We point out that CORGI fixed-order contour-improved results for R and the Higgs decay width, can be given explicitly in terms of the Lambert-W function and hypergeometric functions, avoiding the need for numerical integration.Comment: 33 pages, 8 figure