Educating students with disabilities who study at the university

In this article the authors aim to analyze the ways of educating students with disabilities. Research activities at the university are the main type of educational and professional activities for students. Students with disabilities have difficulties in organizing research activities. Students have difficulties in self-regulation, their goals in research activities related to internal well-bein

Experience of Developing a database of storytellers of the Yakut Epos

The results of the analysis of the basic principles of compiling the database “Olonkhosuts of Yakutia of the 17th—20th centuries” — about the storytellers of the Yakut national epic are presented. The relevance of the research is determined by some difficulties in the systematization and design of the information content of the repository. A brief overview of the history of the study of the personalities of Yakut storytellers is given, the stages of database development are discussed in detail. It is noted that as a result of the generalization of the material a reference book that contains more than 1300 names of storytellers of the 17th-20th centuries was published by the team of the Olonkho Research Institute of M. K. Ammosov North-Eastern Federal University. Problems identified in the process of filling in the cells are described. Particular attention is paid to entering data in the national language, their transliteration and translation into Russian. The definition of the types of the second names of olonkhosuts is given, the expediency of allocating a separate field for nicknames-pseudonyms reflecting the status and popular recognition of the talent of the narrator is substantiated. A sample database table on olonkhosuts is presented. As a result of the study, the parameters for selecting data for inclusion in the repository were compiled, the need for additional research work to identify the facts of the change of residence of olonkhosuts was determined, and recommendations were proposed for improving the principles of information content of the database

The competency levels of disabled students who study in university

The article is devoted to the problem of inclusive education of students with disabilities at the university. The article analyses the study of the readiness of students with disabilities to research activitie

Efficiency of local therapy with the use of a new preparation for oral care at periodontitis in the course of hyperpeptic gastritis after tobacco smoke intoxication

Periodontal diseases, arising against a background of stomach pathology at tobacco addiction remain an acute problem of modern dentistry. The aim of the work is an experimental study of efficiency of application of the new preparation for oral care during treatment of periodontitis simulated against a background of hyperpeptic gastritis under conditions of intoxication by tobacco smoke. At the first stage all experimental animals were divided into 4 groups: І - intact, II - with simulated periodontitis, III - with simulated periodontitis against a background of simulated hyperpeptic gastritis, IV - with simulated periodontitis against a background of hyperpeptic gastritis under conditions of tobacco smoking. Biochemical researches at periodontitis in rats were conducted for determination of influencing stomach pathology and tobacco smoke. On the II stage efficiency of local therapy was studied with the use of the new preparation for oral care and a comparator agent.Results: At experimental periodontitis against a background of hyperpeptic gastritis under conditions of smoking the considerable changes in periodontal tissues typical for the inflammatory process develop. The local therapy at rats with the use of the new preparation resulted in accelerating removing harmful influence of damaging factors and restoring the state of periodontal tissues, than in case of application of the comparator agent. The efficiency of the new preparation consists in normalizing influence on processes of lipid peroxidation, inflammation and activation of the protective systems of oral cavity during periodontitis which arises up against a background of hyperpeptic gastritis

Nanoscale investigation of polymer cement concretes by small angle neutron scattering

An analysis of dense cements, such as polymer cement concrete, is made to produce original innovative components for different types of constructing materials. These materials present good functional properties (ageing resistance, crack formation resistance, hardness, and stability of mechanical modules) and can be used for various applications. In this paper, experimental tests on Portland cement with added γ-Al 2 O 3 and redispersible dry polymer performed using small angle neutron scattering are reported. The objective of the investigation was to assess the key parameters of the material (e.g., porosity, fractal dimensions, and size distribution) at the nanoscale level as well as to obtain useful structural information for expanding the possibility of applications. The results obtained can contribute to the optimisation of the consistency of the material, the design of operating conditions of elements of structures and facilities, and the design of the procedures that support ecological criteria and enhance quality and safety levels. © 2017 Walter de Gruyter GmbH, Berlin/Boston

dSAP18 and dHDAC1 contribute to the functional regulation of the Drosophila Fab-7 element

It was described earlier that the Drosophila GAGA factor [Trithorax-like (Trl)] interacts with dSAP18, which, in mammals, was reported to be a component of the Sin3–HDAC co-repressor complex. GAGA–dSAP18 interaction was proposed to contribute to the functional regulation of the bithorax complex (BX-C). Here, we show that mutant alleles of Trl, dsap18 and drpd3/hdac1 enhance A6-to-A5 transformation indicating a contribution to the regulation of Abd-B expression at A6. In A6, expression of Abd-B is driven by the iab-6 enhancer, which is insulated from iab-7 by the Fab-7 element. Here, we report that GAGA, dSAP18 and dRPD3/HDAC1 co-localize to ectopic Fab-7 sites in polytene chromosomes and that mutant Trl, dsap18 and drpd3/hdac1 alleles affect Fab-7-dependent silencing. Consistent with these findings, chromatin immunoprecipitation analysis shows that, in Drosophila embryos, the endogenous Fab-7 element is hypoacetylated at histones H3 and H4. These results indicate a contribution of GAGA, dSAP18 and dRPD3/HDAC1 to the regulation of Fab-7 function

Cytogenetic aspects of occupational carcinogenic hazard

© 2016,International Journal of Pharmacy and Technology. All rights reserved.The effect of chemical factors of the production environment is studied with a wide range of test systems,among which the short-term tests with high sensitivity are in the foreground. We conducted a study to assess the cytogenetic status of servicemen. Micronucleus test was a convenient method of substance screening that can quickly determine the presence or absence of various compounds of cytogenetic nature. We have identified a relationship between exposure of occupational hazards and the level of micronuclei in human peripheral blood. Excess in number of micronuclei occurs at almost three times the rate in the retired servicemen. Indicator in this contingent group was 92.7%. Subject to the age,the risk group of the high chance of malignancy development is the people over age 70. 3N micronuclei level in this age group was found in 96.3%. 3N micronuclei level is found in 71.4% of representatives of the employment group of 3-9 years,while in the employment group of 30-39 years - only in 68.7%. Subject to the military force,the risk group of the high chance of malignancy development are missile,ground,and motorized rifle troops

ИННОВАЦИОННЫЕ МЕТОДЫ ЛЕКАРСТВЕННОГО ОБЕСПЕЧЕНИЯ: СОГЛАШЕНИЯ О РАЗДЕЛЕНИИ РИСКОВ

В статье представлены результаты анализа существующих моделей соглашений о разделении рисков (СРР), применяемых в зарубежных странах при возмещении затрат на лекарственное обеспечение населения. Оценены возможности использования СРР в Российской Федерации, с учетом существующего нормативно-правового обеспечения. Рассмотрена роль системы оценки медицинских технологий, как одного из элементов системы принятия решений, необходимого для внедрения СРР. Так же предложены конкретные изменения в существующее законодательство, которое необходимо произвести для успешного внедрения СРР в Российской Федерации