326 research outputs found
Polyunsaturated fatty acids inhibit the expression of the glucose-6-phosphate dehydrogenase gene in primary rat hepatocytes by a nuclear posttranscriptional mechanism
On the observability of the neutrino charge radius
It is shown that the probe-independent charge radius of the neutrino is a
physical observable; as such, it may be extracted from experiment, at least in
principle. This is accomplished by expressing a set of experimental
neutrino-electron cross-sections in terms of the finite charge radius and two
additional gauge- and renormalization-group-invariant quantities, corresponding
to the electroweak effective charge and mixing angle.Comment: 10 pages, 1 figure; a typo in Eq.1 corrected, some comments adde
A new look at the cosmic ray positron fraction
The positron fraction in cosmic rays was found to be a steadily increasing in
function of energy, above 10 GeV. This behaviour contradicts standard
astrophysical mechanisms, in which positrons are secondary particles, produced
in the interactions of primary cosmic rays during the propagation in the
interstellar medium. The observed anomaly in the positron fraction triggered a
lot of excitement, as it could be interpreted as an indirect signature of the
presence of dark matter species in the Galaxy. Alternatively, it could be
produced by nearby astrophysical sources, such as pulsars. Both hypotheses are
probed in this work in light of the latest AMS-02 positron fraction
measurements. The transport of the primary and secondary positrons in the
Galaxy is described using a semi-analytic two-zone model. MicrOMEGAs is used to
model the positron flux generated by dark matter species. The description of
the positron fraction from astrophysical sources is based on the pulsar
observations included in the ATNF catalogue. We find that the mass of the
favoured dark matter candidates is always larger than 500 GeV. The only dark
matter species that fulfils the numerous gamma ray and cosmic microwave
background bounds is a particle annihilating into four leptons through a light
scalar or vector mediator, with a mixture of tau (75%) and electron (25%)
channels, and a mass between 0.5 and 1 TeV. The positron anomaly can also be
explained by a single astrophysical source and a list of five pulsars from the
ATNF catalogue is given. Those results are obtained with the cosmic ray
transport parameters that best fit the B/C ratio. Uncertainties in the
propagation parameters turn out to be very significant. In the WIMP
annihilation cross section to mass plane for instance, they overshadow the
error contours derived from the positron data.Comment: 20 pages, 16 figures, accepted for publication in A&A, corresponds to
published versio
The effects of discreteness of galactic cosmic rays sources
Most studies of GeV Galactic Cosmic Rays (GCR) nuclei assume a steady
state/continuous distribution for the sources of cosmic rays, but this
distribution is actually discrete in time and in space. The current progress in
our understanding of cosmic ray physics (acceleration, propagation), the
required consistency in explaining several GCRs manifestation (nuclei,
,...) as well as the precision of present and future space missions
(e.g. INTEGRAL, AMS, AGILE, GLAST) point towards the necessity to go beyond
this approximation. A steady state semi-analytical model that describes well
many nuclei data has been developed in the past years based on this
approximation, as well as others. We wish to extend it to a time dependent
version, including discrete sources. As a first step, the validity of several
approximations of the model we use are checked to validate the approach: i) the
effect of the radial variation of the interstellar gas density is inspected and
ii) the effect of a specific modeling for the galactic wind (linear vs
constant) is discussed. In a second step, the approximation of using continuous
sources in space is considered. This is completed by a study of time
discreteness through the time-dependent version of the propagation equation. A
new analytical solution of this equation for instantaneous point-like sources,
including the effect of escape, galactic wind and spallation, is presented.
Application of time and space discretness to definite propagation conditions
and realistic distributions of sources will be presented in a future paper.Comment: final version, 8 figures, accepted in ApJ. A misprint in fig 8 labels
has been correcte
Self-Lensing Models of the LMC
All of the proposed explanations for the microlensing events observed towards
the LMC have difficulties. One of these proposed explanations, LMC
self-lensing, which invokes ordinary LMC stars as the long sought-after lenses,
has recently gained considerable popularity as a possible solution to the
microlensing conundrum. In this paper, we carefully examine the set of LMC
self-lensing models. In particular, we review the pertinent observations made
of the LMC, and show how these observations place limits on such self-lensing
models. We find that, given current observational constraints, no purely LMC
disk models are capable of producing optical depths as large as that reported
in the MACHO collaboration 2-year analysis. Besides pure disk, we also consider
alternate geometries, and present a framework which encompasses the previous
studies of LMC self-lensing. We discuss which model parameters need to be
pushed in order for such models to succeed. For example, like previous workers,
we find that an LMC halo geometry may be able to explain the observed events.
However, since all known LMC tracer stellar populations exhibit disk-like
kinematics, such models will have difficulty being reconciled with
observations. For SMC self-lensing, we find predicted optical depths differing
from previous results, but more than sufficient to explain all observed SMC
microlensing. In contrast, for the LMC we find a self-lensing optical depth
contribution between 0.47e-8 and 7.84e-8, with 2.44e-8 being the value for the
set of LMC parameters most consistent with current observations.Comment: 20 pages, Latex, 14 figures, submitted to Ap
Microlensing signature of a white dwarf population in the galactic halo
Microlensing and pixel-lensing surveys play a fundamental role in the
searches for galactic dark matter and in the study of the galactic structure.
Recent observations suggest the presence of a population of old white dwarfs
with high proper motion, probably in the galactic halo, with local mass density
in the range pc, in
addition to the standard galactic stellar disk and dark halo components.
Investigation of the signatures on microlensing results towards the LMC of
these different lens populations, with particular emphasis to white dwarfs, is
the main purpose of the present paper. This is done by evaluating optical depth
and microlensing rate of the various lens populations and then calculating
through a Montecarlo program, the probability that a lens which has caused a
microlensing event of duration belongs to a certain galactic
population. Data obtained by the MACHO Collaboration allow us to set an upper
bound of pc to the local mass density of
white dwarfs distributed in spheroidal models, while for white dwarfs in disk
models all values for the local mass density are in agreement with
observational results.Comment: in press on International Journal of modern Physics
Abundance of hepatic metallothionein mRNA is increased by protein-synthesis inhibitors. Evidence for transcriptional activation and post-transcriptional regulation
On the Importance of Electroweak Corrections for Majorana Dark Matter Indirect Detection
Recent analyses have shown that the inclusion of electroweak corrections can
alter significantly the energy spectra of Standard Model particles originated
from dark matter annihilations. We investigate the important situation where
the radiation of electroweak gauge bosons has a substantial influence: a
Majorana dark matter particle annihilating into two light fermions. This
process is in p-wave and hence suppressed by the small value of the relative
velocity of the annihilating particles. The inclusion of electroweak radiation
eludes this suppression and opens up a potentially sizeable s-wave contribution
to the annihilation cross section. We study this effect in detail and explore
its impact on the fluxes of stable particles resulting from the dark matter
annihilations, which are relevant for dark matter indirect searches. We also
discuss the effective field theory approach, pointing out that the opening of
the s-wave is missed at the level of dimension-six operators and only encoded
by higher orders.Comment: 25 pages, 6 figures. Minor corrections to match version published in
JCA
correlation between clinic pathological features msi pd l1 and survival in resectable gastric cancer looking for prognostic biomarkers
n/
Antideuterons as a Signature of Supersymmetric Dark Matter
Once the energy spectrum of the secondary component is well understood,
measurements of the antiproton cosmic-ray flux at the Earth will be a powerful
way to indirectly probe for the existence of supersymmetric relics in the
galactic halo. Unfortunately, it is still spoilt by considerable theoretical
uncertainties. As shown in this work, searches for low-energy antideuterons
appear in the mean time as a plausible alternative, worth being explored. Above
a few GeV/n, a dozen spallation antideuterons should be collected by the future
AMS experiment on board ISSA. For energies less than about 3 GeV/n, the
antideuteron spallation component becomes negligible and may be supplanted by a
potential supersymmetric signal. If a few low-energy antideuterons are
discovered, this should be seriously taken as a clue for the existence of
massive neutralinos in the Milky Way.Comment: 16 pages, 9 figure
- …