6,714 research outputs found
High spatial resolution and high contrast optical speckle imaging with FASTCAM at the ORM
In this paper, we present an original observational approach, which combines,
for the first time, traditional speckle imaging with image post-processing to
obtain in the optical domain diffraction-limited images with high contrast
(1e-5) within 0.5 to 2 arcseconds around a bright star. The post-processing
step is based on wavelet filtering an has analogy with edge enhancement and
high-pass filtering. Our I-band on-sky results with the 2.5-m Nordic Telescope
(NOT) and the lucky imaging instrument FASTCAM show that we are able to detect
L-type brown dwarf companions around a solar-type star with a contrast DI~12 at
2" and with no use of any coronographic capability, which greatly simplifies
the instrumental and hardware approach. This object has been detected from the
ground in J and H bands so far only with AO-assisted 8-10 m class telescopes
(Gemini, Keck), although more recently detected with small-class telescopes in
the K band. Discussing the advantage and disadvantage of the optical regime for
the detection of faint intrinsic fluxes close to bright stars, we develop some
perspectives for other fields, including the study of dense cores in globular
clusters. To the best of our knowledge this is the first time that high
contrast considerations are included in optical speckle imaging approach.Comment: Proceedings of SPIE conference - Ground-based and Airborne
Instrumentation for Astronomy III (Conference 7735), San Diego 201
A radio and infrared exploration of the Cygnus X-3 environments
To confirm, or rule out, the possible hot spot nature of two previously
detected radio sources in the vicinity of the Cygnus X-3 microquasar.
We present the results of a radio and near infrared exploration of the
several arc-minute field around the well known galactic relativistic jet source
Cygnus X-3 using the Very Large Array and the Calar Alto 3.5~m telescope.
The data this paper is based on do not presently support the hot spot
hypothesis. Instead, our new observations suggest that these sources are most
likely background or foreground objects. Actually, none of them appears to be
even barely extended as would be expected if they were part of a bow shock
structure. Our near infrared observations also include a search for extended
emission in the Bracket (2.166 m) and (2.122 m)
lines as possible tracers of shocked gas in the Cygnus X-3 surroundings. The
results were similarly negative and the corresponding upper limits are
reported.Comment: Accepted for publication in A&A; 5 pages, 4 figure
Chandra X-ray counterpart of KS 1741-293
We aim to investigate the nature of the high energy source KS 1741-293 by
revisiting the radio and infrared associations proposed in the early 1990s. Our
work is mostly based on the analysis of modern survey and archive data,
including the NRAO, MSX, 2MASS and Chandra archives, and catalogues. We also
have obtained deep CCD optical observations by ourselves. The coincidence of KS
1741-293 with an extended radio and far-infrared source, tentatively suggested
in 1994, is no longer supported by modern observational data. Instead, a
Chandra source is the only peculiar object found to be consistent with all
high-energy error circles of KS 1741-293 and we propose it to be its most
likely X-ray counterpart. We also report the existence of a non-thermal radio
nebula in the vicinity of the KS 1741-293 position with the appearance of a
supernova remnant. The possibility of being associated to this X-ray binary is
discussed.Comment: 5 pages, 4 figures, 2 tables. Accepted for publication in Astronomy &
Astrophysic
Discovery of a wide companion near the deuterium burning mass limit in the Upper Scorpius association
We present the discovery of a companion near the deuterium burning mass limit
located at a very wide distance, at an angular separation of 4.6+/-0.1 arcsec
(projected distance of ~ 670 AU) from UScoCTIO108, a brown dwarf of the very
young Upper Scorpius association. Optical and near-infrared photometry and
spectroscopy confirm the cool nature of both objects, with spectral types of M7
and M9.5, respectively, and that they are bona fide members of the association,
showing low gravity and features of youth. Their masses, estimated from the
comparison of their bolometric luminosities and theoretical models for the age
range of the association, are 60+/-20 and 14^{+2}_{-8} MJup, respectively. The
existence of this object around a brown dwarf at this wide orbit suggests that
the companion is unlikely to have formed in a disk based on current planet
formation models. Because this system is rather weakly bound, they did not
probably form through dynamical ejection of stellar embryos.Comment: 10 pages, including 4 figures and 2 table
Live lecture screencast recording: a proposal to simplify the tasks associated with content production for video-teaching
Se trata de un resumen (Abstract) de la contribución. El acuerdo de transferencia de copyright del trabajo completo es incompatible con el depósito del mismo en RIUMA.Se describe la implementación inicial de un método simplificado de grabación en directo de sesiones de clase en asignaturas de las Escuelas de Ingeniería de la Universidad de Málaga. La simplificación se logra al incorporar en la actividad diaria del aula ciertas características típicas de la grabación en diferido de mini videos docentes. En una configuración mínima se graba únicamente el audio y el video en pantalla de la clase, evitando los desafíos técnicos y las dificultades que implica la grabación de otros elementos como la pizarra. Esto implica el uso de anotaciones en pantalla en tiempo real para reemplazar completamente las anotaciones en la pizarra.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.
I Plan Propio Integral de Docencia. Universidad de Málaga.
Universidad de Málaga. Vicerectorado de Personal Docente e Investigador, Proyectos de Innovación Educativa (PIE 17-018
Improved Carbohydrate Metabolism After Bariatric Surgery Raises Antioxidized LDL Antibody Levels in Morbidly Obese Patients
OBJECTIVE—Antioxidized LDL (anti-oxLDL) antibodies have recently been suggested to be protective against the development of diabetes. We measured the changes in anti-oxLDL antibody levels in the inverse situation of improvement in carbohydrate metabolism
High contrast optical imaging of companions: the case of the brown dwarf binary HD-130948BC
High contrast imaging at optical wavelengths is limited by the modest
correction of conventional near-IR optimized AO systems.We take advantage of
new fast and low-readout-noise detectors to explore the potential of fast
imaging coupled to post-processing techniques to detect faint companions to
stars at small separations. We have focused on I-band direct imaging of the
previously detected brown dwarf binary HD130948BC,attempting to spatially
resolve the L2+L2 benchmark system. We used the Lucky-Imaging instrument
FastCam at the 2.5-m Nordic Telescope to obtain quasi diffraction-limited
images of HD130948 with ~0.1" resolution.In order to improve the detectability
of the faint binary in the vicinity of a bright (I=5.19 \pm 0.03) solar-type
star,we implemented a post-processing technique based on wavelet transform
filtering of the image which allows us to strongly enhance the presence of
point-like sources in regions where the primary halo dominates. We detect for
the first time the BD binary HD130948BC in the optical band I with a SNR~9 at
2.561"\pm 0.007" (46.5 AU) from HD130948A and confirm in two independent
dataset that the object is real,as opposed to time-varying residual speckles.We
do not resolve the binary, which can be explained by astrometric results
posterior to our observations that predict a separation below the NOT
resolution.We reach at this distance a contrast of dI = 11.30 \pm 0.11, and
estimate a combined magnitude for this binary to I = 16.49 \pm 0.11 and a I-J
colour 3.29 \pm 0.13. At 1", we reach a detectability 10.5 mag fainter than the
primary after image post-processing. We obtain on-sky validation of a technique
based on speckle imaging and wavelet-transform processing,which improves the
high contrast capabilities of speckle imaging.The I-J colour measured for the
BD companion is slightly bluer, but still consistent with what typically found
for L2 dwarfs(~3.4-3.6).Comment: accepted in A\&
Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
Altres ajuts: Suported by IKERBASQUE, Basque foundation for Science (M.J. Perugorria and J.M. Banales), Spain; "Junta de Castilla y Leon" (J.J.G. Marin: SA06P17); "Diputación Foral Gipuzkoa" (J.M. Banales: DFG15/010, DFG16/004; M.J. Perugorria: DFG18/114, DFG19/081), BIOEF (Basque Foundation for Innovation and Health Research: EiTB Maratoia BIO15/CA/016/BD to J.M. Banales), Department of Health of the Basque Country (J.M. Banales: 2017111010; M.J. Perugorria: 2019111024), and Euskadi RIS3 (J.M. Banales: 2016222001, 2017222014, and 2018222029; 2019222054); La Caixa Scientific Foundation (J.M. Banales: HR17-00601); "Fundación Científica de la Asociación Española Contra el Cáncer" (AECC Scientific Foundation, to J.M. Banales and J.J.G. Marin); and "Centro Internacional sobre el Envejecimiento", Spain (J.J.G. Marin: OLD-HEPAMARKER, 0348-CIE-6-E). A. Santos-Laso by the Basque Government (PRE_2018_2_0195), and Pui Y. Lee-Law by the European Association for the Study of the Liver (EASL; Sheila Sherlock Award). Basque Government (F.P. Cossío: IT-324-07). I. Rivilla had a postdoctoral contract from the Donostia International Physics Center.Background and Aims: Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current surgical and pharmacological approaches are ineffective, and liver transplantation represents the only curative option. Ursodeoxycholic acid (UDCA) and histone deacetylase 6 inhibitors (HDAC6is) have arisen as promising therapeutic strategies, but with partial benefits. Approach and Results: Here, we tested an approach based on the design, synthesis, and validation of a family of UDCA synthetic conjugates with selective HDAC6i capacity (UDCA-HDAC6i). Four UDCA-HDAC6i conjugates presented selective HDAC6i activity, UDCA-HDAC6i #1 being the most promising candidate. UDCA orientation within the UDCA-HDAC6i structure was determinant for HDAC6i activity and selectivity. Treatment of polycystic rats with UDCA-HDAC6i #1 reduced their hepatomegaly and cystogenesis, increased UDCA concentration, and inhibited HDAC6 activity in liver. In cystic cholangiocytes UDCA-HDAC6i #1 restored primary cilium length and exhibited potent antiproliferative activity. UDCA-HDAC6i #1 was actively transported into cells through BA and organic cation transporters. Conclusions: These UDCA-HDAC6i conjugates open a therapeutic avenue for PLDs
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