186 research outputs found

    The impact of theatrical experiences on young adults in Spain

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    This study examines how young adults experience theatre and how this activity impacts their personal development. A total of 305 subjects, between 14 and 29 years old, completed the 'Theatre and me' (T&Y) battery of questions. Correlation and variance analysis were conducted considering age and gender. Older subjects reported that participating in drama activities has a greater impact on their lives, helps them to have a greater proclivity to take risks and to be more open-minded. With respect to gender, girls score higher than boys in 'Tolerance to RiskTaking and Commitment', 'Identity and Consciousness', Expression of Feeling' and 'Escape

    Duals of variable exponent Hörmander spaces (0<pp+10< p^- \le p^+ \le 1) and some applications

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    In this paper we characterize the dual \bigl(\B^c_{p(\cdot)} (\Omega) \bigr)' of the variable exponent H\"or\-man\-der space \B^c_{p(\cdot)} (\Omega) when the exponent p()p(\cdot) satisfies the conditions 0<pp+10 < p^- \le p^+ \le 1, the Hardy-Littlewood maximal operator MM is bounded on Lp()/p0L_{p(\cdot)/p_0} for some 0<p0<p0 < p_0 < p^- and Ω\Omega is an open set in Rn\R^n. It is shown that the dual \bigl(\B^c_{p(\cdot)} (\Omega) \bigr)' is isomorphic to the H\"ormander space \B^{\mathrm{loc}}_\infty (\Omega) (this is the p+1p^+ \le 1 counterpart of the isomorphism \bigl(\B^c_{p(\cdot)} (\Omega) \bigr)' \simeq \B^{\mathrm{loc}}_{\widetilde{p'(\cdot)}} (\Omega), 1<pp+<1 < p^- \le p^+ < \infty, recently proved by the authors) and hence the representation theorem \bigl( \B^c_{p(\cdot)} (\Omega) \bigr)' \simeq l^{\N}_\infty is obtained. Our proof relies heavily on the properties of the Banach envelopes of the steps of \B^c_{p(\cdot)} (\Omega) and on the extrapolation theorems in the variable Lebesgue spaces of entire analytic functions obtained in a precedent paper. Other results for p()pp(\cdot) \equiv p, 0<p<10 < p < 1, are also given (e.g. \B^c_p (\Omega) does not contain any infinite-dimensional qq-Banach subspace with p<q1p < q \le 1 or the quasi-Banach space \B_p \cap \E'(Q) contains a copy of lpl_p when QQ is a cube in Rn\R^n). Finally, a question on complex interpolation (in the sense of Kalton) of variable exponent H\"ormander spaces is proposed.J. Motos is partially supported by grant MTM2011-23164 from the Spanish Ministry of Science and Innovation. The authors wish to thank the referees for the careful reading of the manuscript and for many helpful suggestions and remarks that improved the exposition. In particular, the remark immediately following Theorem 2.1 and the Question 2 were motivated by the comments of one of them.Motos Izquierdo, J.; Planells Gilabert, MJ.; Talavera Usano, CF. (2015). Duals of variable exponent Hörmander spaces (0<pp+10< p^- \le p^+ \le 1) and some applications. Revista- Real Academia de Ciencias Exactas Fisicas Y Naturales Serie a Matematicas. 109(2):657-668. https://doi.org/10.1007/s13398-014-0209-zS6576681092Aboulaich, R., Meskine, D., Souissi, A.: New diffussion models in image processing. Comput. Math. Appl. 56(4), 874–882 (2008)Acerbi, E., Mingione, G.: Regularity results for stationary electro-rheological fluids. Arch. Ration. Mech. Anal. 164(3), 213–259 (2002)Bastero, J.: lql^q l q -subspaces of stable pp p -Banach spaces, 0<p10 < p \le 1 0 < p ≤ 1 . Arch. Math. (Basel) 40, 538–544 (1983)Boas, R.P.: Entire functions. Academic Press, London (1954)Boza, S.: Espacios de Hardy discretos y acotación de operadores. Dissertation, Universitat de Barcelona (1998)Cruz-Uribe, D., Fiorenza, A.: Variable Lebesgue spaces, foundations and harmonic analysis. Birkhäuser, Basel (2013)Cruz-Uribe, D.: SFO, A. Fiorenza, J. M. Martell, C. Pérez: The boundedness of classical operators on variable LpL^p L p spaces. Ann. Acad. Sci. Fenn. Math. 31, 239–264 (2006)Diening, L., Harjulehto, P., Hästö, P., Růžička, M.: Lebesgue and sobolev spaces with variable exponents. lecture notes in mathematics, vol. 2007. Springer, Berlin, Heidelberg (2011)Hörmander, L.: The analysis of linear partial operators II, Grundlehren 257. Springer, Berlin, Heidelberg (1983)Hörmander, L.: The analysis of linear partial operators I, Grundlehren 256. Springer, Berlin, Heidelberg (1983)Kalton, N.J., Peck, N.T., Roberts, J.W.: An FF F -space sampler, London Mathematical Society Lecture Notes, vol. 89. Cambridge University Press, Cambridge (1985)Kalton, N.J.: Banach envelopes of non-locally convex spaces. Canad. J. Math. 38(1), 65–86 (1986)Kalton, N.J., Mitrea, M.: Stability results on interpolation scales of quasi-Banach spaces and applications. Trans. Am. Math. Soc. 350(10), 3903–3922 (1998)Kalton, N.J.: Quasi-Banach spaces, Handbook of the Geometry of Banach Spaces, vol. 2. In: Johnson, W.B., Lindenstrauss, J. (eds.), pp. 1099–1130. Elsevier, Amsterdam (2003)Köthe, G.: Topological vector spaces I. Springer, Berlin, Heidelberg (1969)Motos, J., Planells, M.J., Talavera, C.F.: On variable exponent Lebesgue spaces of entire analytic functions. J. Math. Anal. Appl. 388, 775–787 (2012)Motos, J., Planells, M.J., Talavera, C.F.: A note on variable exponent Hörmander spaces. Mediterr. J. Math. 10, 1419–1434 (2013)Stiles, W.J.: Some properties of lpl_p l p , 0<p<10 < p < 1 0 < p < 1 . Studia Math. 42, 109–119 (1972)Triebel, H.: Theory of function spaces. Birkhäuser, Basel (1983)Vogt, D.: Sequence space representations of spaces of test functions and distributions. In: Zapata, G.I. (ed.) Functional analysis, holomorphy and approximation theory, Lecture Notes in Pure and Applied Mathematics, vol. 83, pp. 405–443 (1983

    Estimation of biomass of horse mackerel (Trachurus trachurus L.) in northern-Spain ( Nortbern IXa and VIIIc ) using the daily egg production method.

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    In order to estimate the spawning stock biomass of horse mackerel in the North Atlantic Spanish waters, a series of egg and adult cruises were carried out by lEO (Instituto Español de Oceanografía) and AZTI -SIO (Instituto de Investigación y Tecnología para la Oceanografía, Pesca y Alimentación) . The survey was carried out from 23 April to 25 May 1992. A total of 627 plankton samples and 37 adults samples were collected. A total daily egg production of 3.3 X 1012 egg (SE = 7.26 X 1011 , CV = 0.22) was estimated for the whole area sarnpled (ICES Division Vlllc and subdivision northern IXa north). The estirnate of horse mackerel spawning biornass ranged from 486,549 tons (CV = 0.34, when using adult pararneter estirnates exclusively frorn the Spanish survey, down to 368,814 tn (C = 0.32), when alternatively using an estimate of relative batch fecundity from the southern region of horse rnackerel western stock

    Surgical treatment for colorectal cancer: Analysis of the influence of an enhanced recovery programme on long-term oncological outcomes-a study protocol for a prospective, multicentre, observational cohort study

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    Introduction The evidence currently available from enhanced recovery after surgery (ERAS) programmes concerns their benefits in the immediate postoperative period, but there is still very little evidence as to whether their correct implementation benefits patients in the long term. The working hypothesis here is that, due to the lower response to surgical aggression and lower rates of postoperative complications, ERAS protocols can reduce colorectal cancer-related mortality. The main objective of this study is to analyse the impact of an ERAS programme for colorectal cancer on 5-year survival. As secondary objectives, we propose to analyse the weight of each of the predefined items in the oncological results as well as the quality of life. Methods and analysis A multicentre prospective cohort study was conducted in patients older than 18 years of age who are scheduled to undergo surgery for colorectal cancer. The study involved 12 hospitals with an implemented enhanced recovery protocol according to the guidelines published by the Spanish National Health Service. The intervention group includes patients with a minimum implementation level of 70%, and the control group includes those who fail to reach this level. Compliance will be studied using 18 key performance indicators, and the results will be analysed using cancer survival indicators, including overall survival, cancer-specific survival and relapse-free survival. The time to recurrence, perioperative morbidity and mortality, hospital stay and quality of life will also be studied, the latter using the validated EuroQol Five questionnaire. The propensity index method will be used to create comparable treatment and control groups, and a multivariate regression will be used to study each variable. The Kaplan-Meier estimator will be used to estimate survival and the log-rank test to make comparisons. A p value of less than 0.05 (two-tailed) will be considered to be significant. Ethics and dissemination Ethical approval for this study was obtained from the Aragon Ethical Committee (C.P.-C.I. PI20/086) on 4 March 2020. The findings of this study will be submitted to peer-reviewed journals (BMJ Open, JAMA Surgery, Annals of Surgery, British Journal of Surgery). Abstracts will be submitted to relevant national and international meetings. Trial registration number NCT04305314

    Surgical treatment for colorectal cancer: Analysis of the influence of an enhanced recovery programme on long-term oncological outcomes-a study protocol for a prospective, multicentre, observational cohort study

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    Introduction The evidence currently available from enhanced recovery after surgery (ERAS) programmes concerns their benefits in the immediate postoperative period, but there is still very little evidence as to whether their correct implementation benefits patients in the long term. The working hypothesis here is that, due to the lower response to surgical aggression and lower rates of postoperative complications, ERAS protocols can reduce colorectal cancer-related mortality. The main objective of this study is to analyse the impact of an ERAS programme for colorectal cancer on 5-year survival. As secondary objectives, we propose to analyse the weight of each of the predefined items in the oncological results as well as the quality of life. Methods and analysis A multicentre prospective cohort study was conducted in patients older than 18 years of age who are scheduled to undergo surgery for colorectal cancer. The study involved 12 hospitals with an implemented enhanced recovery protocol according to the guidelines published by the Spanish National Health Service. The intervention group includes patients with a minimum implementation level of 70%, and the control group includes those who fail to reach this level. Compliance will be studied using 18 key performance indicators, and the results will be analysed using cancer survival indicators, including overall survival, cancer-specific survival and relapse-free survival. The time to recurrence, perioperative morbidity and mortality, hospital stay and quality of life will also be studied, the latter using the validated EuroQol Five questionnaire. The propensity index method will be used to create comparable treatment and control groups, and a multivariate regression will be used to study each variable. The Kaplan-Meier estimator will be used to estimate survival and the log-rank test to make comparisons. A p value of less than 0.05 (two-tailed) will be considered to be significant. Ethics and dissemination Ethical approval for this study was obtained from the Aragon Ethical Committee (C.P.-C.I. PI20/086) on 4 March 2020. The findings of this study will be submitted to peer-reviewed journals (BMJ Open, JAMA Surgery, Annals of Surgery, British Journal of Surgery). Abstracts will be submitted to relevant national and international meetings.The present research study was awarded a Ministerio de Ciencia e Innovación health research project grant (PI19/00291) from the Carlos III Institute of the Spanish National Health Service as part of the 2019 call for Strategic Action in Health

    Measurement of Upper Limb Range of Motion Using Wearable Sensors: A Systematic Review.

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    Background: Wearable sensors are portable measurement tools that are becoming increasingly popular for the measurement of joint angle in the upper limb. With many brands emerging on the market, each with variations in hardware and protocols, evidence to inform selection and application is needed. Therefore, the objectives of this review were related to the use of wearable sensors to calculate upper limb joint angle. We aimed to describe (i) the characteristics of commercial and custom wearable sensors, (ii) the populations for whom researchers have adopted wearable sensors, and (iii) their established psychometric properties. Methods: A systematic review of literature was undertaken using the following data bases: MEDLINE, EMBASE, CINAHL, Web of Science, SPORTDiscus, IEEE, and Scopus. Studies were eligible if they met the following criteria: (i) involved humans and/or robotic devices, (ii) involved the application or simulation of wearable sensors on the upper limb, and (iii) calculated a joint angle. Results: Of 2191 records identified, 66 met the inclusion criteria. Eight studies compared wearable sensors to a robotic device and 22 studies compared to a motion analysis system. Commercial (n = 13) and custom (n = 7) wearable sensors were identified, each with variations in placement, calibration methods, and fusion algorithms, which were demonstrated to influence accuracy. Conclusion: Wearable sensors have potential as viable instruments for measurement of joint angle in the upper limb during active movement. Currently, customised application (i.e. calibration and angle calculation methods) is required to achieve sufficient accuracy (error < 5°). Additional research and standardisation is required to guide clinical application

    Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration

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    Varicella zoster virus (VZV) is a highly prevalent human pathogen that establishes latency in neurons of the peripheral nervous system. Primary infection causes varicella whereas reactivation results in zoster, which is often followed by chronic pain in adults. Following infection of epithelial cells in the respiratory tract, VZV spreads within the host by hijacking leukocytes, including T cells, in the tonsils and other regional lymph nodes, and modifying their activity. In spite of its importance in pathogenesis, the mechanism of dissemination remains poorly understood. Here we addressed the influence of VZV on leukocyte migration and found that the purified recombinant soluble ectodomain of VZV glycoprotein C (rSgC) binds chemokines with high affinity. Functional experiments show that VZV rSgC potentiates chemokine activity, enhancing the migration of monocyte and T cell lines and, most importantly, human tonsillar leukocytes at low chemokine concentrations. Binding and potentiation of chemokine activity occurs through the C-terminal part of gC ectodomain, containing predicted immunoglobulin-like domains. The mechanism of action of VZV rSgC requires interaction with the chemokine and signalling through the chemokine receptor. Finally, we show that VZV viral particles enhance chemokine-dependent T cell migration and that gC is partially required for this activity. We propose that VZV gC activity facilitates the recruitment and subsequent infection of leukocytes and thereby enhances VZV systemic dissemination in humans
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