Investment games in Crowdfunding platforms -Extended version

International audienceWe analyze the behavior of investors who have to decide on which projects to support in a crowdfunding platform. We model the behaviour of different sets of funders, as reported by crowdfunding literature, and also the behavior of utility-maximizing funders as a stochastic game. The founders' behaviour is also modeled as a Stackelberg game. Our results are illustrated by a numerical performance analysis which provides several insights into the choice of investment strategies

Environmental friendly mobile radio networks: Approaches of the European OPERA-Net 2 project

International audienceReducing the overall environmental impact of mobile radio networks is a central factor in achieving improved mobile services whilst at the same time enabling a growing telecommunications industry in emerging markets. The OPERA-Net-2 (Optimising Power Efficiency in Mobile Radio Networks 2) project concentrates on this challenge, addressing both energy and material efficiencies of 3G, 4G and heterogeneous networks, while also considering the use of renewable energy sources. This paper presents an insight into the project after its first year and discusses research trends in `green communications networks' for the future

Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation

Despite advances in supportive therapy to prevent complications of sickle cell disease (SCD), access to care is not universal. Hematopoietic cell transplantation is, to date, the only curative therapy for SCD, but its application is limited by availability of a suitable HLA-matched donor and lack of awareness of the benefits of transplant. Included in this study are 1000 recipients of HLA-identical sibling transplants performed between 1986 and 2013 and reported to the European Society for Blood and Marrow Transplantation, Eurocord, and the Center for International Blood and Marrow Transplant Research. The primary endpoint was event-free survival, defined as being alive without graft failure; risk factors were studied using a Cox regression models. The median age at transplantation was 9 years, and the median follow-up was longer than 5 years. Most patients received a myeloablative conditioning regimen (n = 873; 87%); the remainder received reduced-intensity conditioning regimens (n = 125; 13%). Bone marrow was the predominant stem cell source (n = 839; 84%); peripheral blood and cord blood progenitors were used in 73 (7%) and 88 (9%) patients, respectively. The 5-year event-free survival and overall survival were 91.4% (95% confidence interval, 89.6%-93.3%) and 92.9% (95% confidence interval, 91.1%-94.6%), respectively. Event-free survival was lower with increasing age at transplantation (hazard ratio [HR], 1.09; P < .001) and higher for transplantations performed after 2006 (HR, 0.95; P = .013). Twenty-three patients experienced graft failure, and 70 patients (7%) died, with the most common cause of death being infection. The excellent outcome of a cohort transplanted over the course of 3 decades confirms the role of HLA-identical sibling transplantation for children and adults with SCD