Flexible time course of spatial frequency use during scene categorization

Human observers can quickly and accurately categorize scenes. This remarkable ability is related to the usage of information at different spatial frequencies (SFs) following a coarse-to-fine pattern: Low SFs, conveying coarse layout information, are thought to be used earlier than high SFs, representing more fine-grained information. Alternatives to this pattern have rarely been considered. Here, we probed all possible SF usage strategies randomly with high resolution in both the SF and time dimensions at two categorization levels. We show that correct basic-level categorizations of indoor scenes are linked to the sampling of relatively high SFs, whereas correct outdoor scene categorizations are predicted by an early use of high SFs and a later use of low SFs (fine-to-coarse pattern of SF usage). Superordinate-level categorizations (indoor vs. outdoor scenes) rely on lower SFs early on, followed by a shift to higher SFs and a subsequent shift back to lower SFs in late stages. In summary, our results show no consistent pattern of SF usage across tasks and only partially replicate the diagnostic SFs found in previous studies. We therefore propose that SF sampling strategies of observers differ with varying stimulus and task characteristics, thus favouring the notion of flexible SF usage

Antimony release and volatilization from rice paddy soils: Field and microcosm study.

The fate of antimony (Sb) in submerged soils and the impact of common agricultural practices (e.g., manuring) on Sb release and volatilization is understudied. We investigated porewater Sb release and volatilization in the field and laboratory for three rice paddy soils. In the field study, the porewater Sb concentration (up to 107.1 μg L-1) was associated with iron (Fe) at two sites, and with pH, Fe, manganese (Mn), and sulfate (SO42-) at one site. The surface water Sb concentrations (up to 495.3 ± 113.7 μg L-1) were up to 99 times higher than the regulatory values indicating a potential risk to aquaculture and rice agriculture. For the first time, volatile Sb was detected in rice paddy fields using a validated quantitative method (18.1 ± 5.2 to 217.9 ± 160.7 mg ha-1 y-1). We also investigated the influence of two common rice agriculture practices (flooding and manuring) on Sb release and volatilization in a 56-day microcosm experiment using the same soils from the field campaign. Flooding induced an immediate, but temporary, Sb release into the porewater that declined with SO42-, indicating that SO42- reduction may reduce porewater Sb concentrations. A secondary Sb release, corresponding to Fe reduction in the porewater, was observed in some of the microcosms. Our results suggest flooding-induced Sb release into rice paddy porewaters is temporary but relevant. Manuring the soils did not impact the porewater Sb concentration but did enhance Sb volatilization. Volatile Sb (159.6 ± 108.4 to 2237.5 ± 679.7 ng kg-1 y-1) was detected in most of the treatments and was correlated with the surface water Sb concentration. Our study indicates that Sb volatilization could be occurring at the soil-water interface or directly in the surface water and highlights that future works should investigate this potentially relevant mechanism

Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina

International audienceSeveral preclinical studies have investigated the potential of algal channelrhodopsin and human melanopsin as optogenetic tools for vision restoration. In the present study, we assessed the potentially deleterious effects of long-term expression of these optogenes on the diseased retina in a large animal model of retinal degeneration, the RPE65-deficient Briard dog model of Leber congenital amaurosis. Intravitreal injection of adeno-associated virus vectors expressing channelrhodopsin and melanopsin had no effect on retinal thickness over a 16-month period post injection. Our data support the safety of the optogenetic approach for the treatment of blindness

Long-term expression of melanopsin and channelrhodopsin causes no gross alterations in the dystrophic dog retina

International audienceSeveral preclinical studies have investigated the potential of algal channelrhodopsin and human melanopsin as optogenetic tools for vision restoration. In the present study, we assessed the potentially deleterious effects of long-term expression of these optogenes on the diseased retina in a large animal model of retinal degeneration, the RPE65-deficient Briard dog model of Leber congenital amaurosis. Intravitreal injection of adeno-associated virus vectors expressing channelrhodopsin and melanopsin had no effect on retinal thickness over a 16-month period post injection. Our data support the safety of the optogenetic approach for the treatment of blindness