629 research outputs found
Order-disorder transition in nanoscopic semiconductor quantum rings
Using the path integral Monte Carlo technique we show that semiconductor
quantum rings with up to six electrons exhibit a temperature, ring diameter,
and particle number dependent transition between spin ordered and disordered
Wigner crystals. Due to the small number of particles the transition extends
over a broad temperature range and is clearly identifiable from the electron
pair correlation functions.Comment: 4 pages, 5 figures, For recent information on physics of small
systems see http://www.smallsystems.d
Classification of phase transitions of finite Bose-Einstein condensates in power law traps by Fisher zeros
We present a detailed description of a classification scheme for phase
transitions in finite systems based on the distribution of Fisher zeros of the
canonical partition function in the complex temperature plane. We apply this
scheme to finite Bose-systems in power law traps within a semi-analytic
approach with a continuous one-particle density of states for different values of and to a three dimensional harmonically
confined ideal Bose-gas with discrete energy levels. Our results indicate that
the order of the Bose-Einstein condensation phase transition sensitively
depends on the confining potential.Comment: 7 pages, 9 eps-figures, For recent information on physics of small
systems see "http://www.smallsystems.de
SeeBridge information delivery manual (IDM) for next generation bridge inspection
Innovative solutions for rapid and intelligent survey and assessment methods are required in maintenance, repair, retrofit and rebuild of enormous numbers of bridges in service throughout the world. Motivated by this need, a next-generation integrated bridge inspection system named SeeBridge is proposed. To frame the system, an Information Delivery Manual (IDM) was compiled to specify the technical components, activities and information exchanges in the SeeBridge process. The IDM supports development of the system by rigorously defining the information and data repositories that structure bridge engineers' knowledge. The SeeBridge process is mapped, parts of the data repositories are presented and the future use of the IDM is discussed
3D Geometric Analysis of Tubular Objects based on Surface Normal Accumulation
This paper proposes a simple and efficient method for the reconstruction and
extraction of geometric parameters from 3D tubular objects. Our method
constructs an image that accumulates surface normal information, then peaks
within this image are located by tracking. Finally, the positions of these are
optimized to lie precisely on the tubular shape centerline. This method is very
versatile, and is able to process various input data types like full or partial
mesh acquired from 3D laser scans, 3D height map or discrete volumetric images.
The proposed algorithm is simple to implement, contains few parameters and can
be computed in linear time with respect to the number of surface faces. Since
the extracted tube centerline is accurate, we are able to decompose the tube
into rectilinear parts and torus-like parts. This is done with a new linear
time 3D torus detection algorithm, which follows the same principle of a
previous work on 2D arc circle recognition. Detailed experiments show the
versatility, accuracy and robustness of our new method.Comment: in 18th International Conference on Image Analysis and Processing,
Sep 2015, Genova, Italy. 201
The Origins of Phase Transitions in Small Systems
The identification and classification of phases in small systems, e.g.
nuclei, social and financial networks, clusters, and biological systems, where
the traditional definitions of phase transitions are not applicable, is
important to obtain a deeper understanding of the phenomena observed in such
systems. Within a simple statistical model we investigate the validity and
applicability of different classification schemes for phase transtions in small
systems. We show that the whole complex temperature plane contains necessary
information in order to give a distinct classification.Comment: 3 pages, 4 figures, revtex 4 beta 5, for further information see
http://www.smallsystems.d
Discontinuing atovaquone/proguanil prophylaxis ad-hoc post-exposure and during-travel dose-sparing prophylactic regimens against P. falciparum malaria: an update with pointers for future research
© 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)Background: Atovaquone/proguanil (AP) is a highly effective malaria chemoprophylaxis combination. According to current guidelines, AP is taken once daily during, and continued for seven days post exposure. A systematic review by Savelkoel et al. summarised data up to 2017 on abbreviated AP regimens, and concluded that discontinuing AP upon return may be effective, although the available data was insufficient to modify current recommendations. The same applies to other studies evaluating during-travel dose-sparing regimens.
Methods: A literature search in Pubmed and Embase was performed including search terms related to AP prophylaxis and pharmacokinetics to search for recent studies on abbreviated AP regimens published since 2017.
Results: Since the 2017 review, no new studies assessing discontinuing AP ad-hoc post-exposure prophylaxis have been published. Two new studies were identified assessing other abbreviated AP regimens; one investigated a twice-weekly AP regimen in 32 travellers, and one a three-day AP course in therapeutic dose (1000/400 mg) prior to exposure in 215 travellers. No malaria cases were detected in the study participants adhering to these regimens.
Conclusions: Further research would be needed if the research question is considered of sufficient importance to facilitate evidence-based decision-making to modify current guidelines, as efficacy studies in travellers are fraught with confounders. We recommend human challenge trials to study abbreviated AP regimens pertaining to malaria chemoprophylaxis as they allow for rational, subject number, time- and cost-saving trial designs.info:eu-repo/semantics/publishedVersio
Variability of aerosol, gaseous pollutants and meteorological characteristics associated with changes in air mass origin at the SW Atlantic coast of Iberia
Measurements of the ambient aerosol were performed at the Southern coast of Spain, within the framework of the DOMINO (<b>D</b>iel <b>O</b>xidant <b>M</b>echanisms <b>I</b>n relation to <b>N</b>itrogen <b>O</b>xides) project. The field campaign took place from 20 November until 9 December 2008 at the atmospheric research station "El Arenosillo" (37°5'47.76" N, 6°44'6.94" W). As the monitoring station is located at the interface between a natural park, industrial cities (Huelva, Seville) and the Atlantic Ocean, a variety of physical and chemical parameters of aerosols and gas phase could be characterized in dependency on the origin of air masses. Backwards trajectories were examined and compared with local meteorology to classify characteristic air mass types for several source regions. Aerosol number and mass as well as polycyclic aromatic hydrocarbons and black carbon concentrations were measured in PM<sub>1</sub> and size distributions were registered covering a size range from 7 nm up to 32 μm. The chemical composition of the non-refractory submicron aerosol (NR-PM<sub>1</sub>) was measured by means of an Aerosol Mass Spectrometer (Aerodyne HR-ToF-AMS). Gas phase analyzers monitored various trace gases (O<sub>3</sub>, SO<sub>2</sub>, NO, NO<sub>2</sub>, CO<sub>2</sub>) and a weather station provided meteorological parameters. <br><br> Lowest average submicron particle mass and number concentrations were found in air masses arriving from the Atlantic Ocean with values around 2 μg m<sup>−3</sup> and 1000 cm<sup>−3</sup>. These mass concentrations were about two to four times lower than the values recorded in air masses of continental and urban origins. For some species PM<sub>1</sub>-fractions in marine air were significantly larger than in air masses originating from Huelva, a closely located city with extensive industrial activities. The largest fraction of sulfate (54%) was detected in marine air masses and was to a high degree not neutralized. In addition, small concentrations of methanesulfonic acid (MSA), a product of biogenic dimethyl sulfate (DMS) emissions, could be identified in the particle phase. <br><br> In all air masses passing the continent the organic aerosol fraction dominated the total NR-PM<sub>1</sub>. For this reason, using Positive Matrix Factorization (PMF) four organic aerosol (OA) classes that can be associated with various aerosol sources and components were identified: a highly-oxygenated OA is the major component (43% OA) while semi-volatile OA accounts for 23%. A hydrocarbon-like OA mainly resulting from industries, traffic and shipping emissions as well as particles from wood burning emissions also contribute to total OA and depend on the air mass origin. <br><br> A significant variability of ozone was observed that depends on the impact of different air mass types and solar radiation
Symmetries of microcanonical entropy surfaces
Symmetry properties of the microcanonical entropy surface as a function of
the energy and the order parameter are deduced from the invariance group of the
Hamiltonian of the physical system. The consequences of these symmetries for
the microcanonical order parameter in the high energy and in the low energy
phases are investigated. In particular the breaking of the symmetry of the
microcanonical entropy in the low energy regime is considered. The general
statements are corroborated by investigations of various examples of classical
spin systems.Comment: 15 pages, 5 figures include
Partition Functions in Statistical Mechanics, Symmetric Functions, and Group Representations
Partition functions for non-interacting particles are known to be symmetric
functions. It is shown that powerful group-theoretical techniques can be used
not only to derive these relationships, but also to significantly simplify
calculation of the partition functions for particles that carry internal
quantum numbers. The partition function is shown to be a sum of one or more
group characters. The utility of character expansions in calculating the
partition functions is explored. Several examples are given to illustrate these
techniques.Comment: 16 pages of RevTe
Application of mobile aerosol and trace gas measurements for the investigation of megacity air pollution emissions: the Paris metropolitan area
For the investigation of megacity emission development and the impact outside the
source region, mobile aerosol and trace gas measurements were carried out in
the Paris metropolitan area between 1 July and 31 July 2009 (summer
conditions) and 15 January and 15 February 2010 (winter conditions) in the
framework of the European Union FP7 MEGAPOLI project. Two mobile
laboratories, MoLa and MOSQUITA, were deployed, and here an overview of these
measurements and an investigation of the applicability of such measurements
for the analysis of megacity emissions are presented. Both laboratories
measured physical and chemical properties of fine and ultrafine aerosol
particles as well as gas phase constituents of relevance for urban pollution
scenarios. The applied measurement strategies include cross-section
measurements for the investigation of plume structure and quasi-Lagrangian
measurements axially along the flow of the city's pollution plume to study
plume aging processes. Results of intercomparison measurements between the
two mobile laboratories represent the adopted data quality assurance
procedures. Most of the compared measurement devices show sufficient
agreement for combined data analysis. For the removal of data contaminated by
local pollution emissions a video tape analysis method was applied. Analysis
tools like positive matrix factorization and peak integration by key analysis
applied to high-resolution time-of-flight aerosol mass spectrometer data are
used for in-depth data analysis of the organic particulate matter. Several
examples, including a combination of MoLa and MOSQUITA measurements
on a cross section through the Paris emission plume, are provided to demonstrate
how such mobile measurements can be used to investigate the emissions of a
megacity. A critical discussion of advantages and limitations of mobile
measurements for the investigation of megacity emissions completes this work
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