397 research outputs found

    Extending OmpSs for OpenCL kernel co-execution in heterogeneous systems

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    © 2017 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes,creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Heterogeneous systems have a very high potential performance but present difficulties in their programming. OmpSs is a well known framework for task based parallel applications, which is an interesting tool to simplify the programming of these systems. However, it does not support the co-execution of a single OpenCL kernel instance on several compute devices. To overcome this limitation, this paper presents an extension of the OmpSs framework that solves two main objectives: the automatic division of datasets among several devices and the management of their memory address spaces. To adapt to different kinds of applications, the data division can be performed by the novel HGuided load balancing algorithm or by the well known Static and Dynamic. All this is accomplished with negligible impact on the programming. Experimental results reveal that there is always one load balancing algorithm that improves the performance and energy consumption of the system.This work has been supported by the University of Cantabria with grant CVE-2014-18166, the Generalitat de Catalunya under grant 2014-SGR-1051, the Spanish Ministry of Economy, Industry and Competitiveness under contracts TIN2016- 76635-C2-2-R (AEI/FEDER, UE) and TIN2015-65316-P. The Spanish Government through the Programa Severo Ochoa (SEV-2015-0493). The European Research Council under grant agreement No 321253 European Community’s Seventh Framework Programme [FP7/2007-2013] and Horizon 2020 under the Mont-Blanc Projects, grant agreement n 288777, 610402 and 671697 and the European HiPEAC Network.Peer ReviewedPostprint (published version

    Morphological and chemical analysis of male scent organs in the butterfly genus Pyrgus (Lepidoptera: Hesperiidae)

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    Chemical communication in the family Hesperiidae (Lepidoptera) is practically unstudied, even though this group includes approximately 4,000 species and represents a fifth of the world's butterfly fauna. We present the first comparative morphological and chemical analysis of scent organs for nine species in the genus Pyrgus, the most species-rich hesperiid genus in the Palearctic region. Our results show that the morphology of the two main male scent organs - the costal fold and the tibial tufts - does not differ between species. The chemical analyses detected a total of 125 different compounds exclusively present in these organs. We document great interspecific differences and much narrower intraspecific variability in the chemical profiles. The dynamics of chemical versus genetic distances indicate two different phases: a faster (but more variable) initial chemical divergence at lower genetic divergences (probably related to speciation) and a slower but more constant differentiation (drift). As a result most species can be identified based on their chemical profiles, except for a closely related species pair (P. malvae/P. malvoides) for which hybridisation is common in the contact zone. Our results suggest that the Hesperiidae is a group with great potential for the study of chemical communication that deserves further attention. © 2014 Gesellschaft für Biologische Systematik.Funding for this research was provided by Universitat Autònoma de Barcelona (project EME2007-33 to J.L.H.-R., R.B. and R.V.) and by the Spanish Ministerio de Ciencia e Innovación (project CGL2010-21226/BOS to J.L.H.-R. and R.V. and project CGL2004-04680-c10-08/BOS to M.L.M.).Peer Reviewe

    Highly Adiabatic Time-Optimal Quantum Driving at Low Energy Cost

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    Time-efficient control schemes for manipulating quantum systems are of great importance in quantum technologies, where environmental forces rapidly degrade the quality of pure states over time. In this Letter, we formulate an approach to time-optimal control that circumvents the boundary-value problem that plagues the quantum brachistochrone equation at the expense of relaxing the form of the control Hamiltonian. In this setting, a coupled system of equations, one for the control Hamiltonian and another one for the duration of the protocol, realizes an ansatz-free approach to quantum control theory. We show how driven systems, in the form of a Landau-Zener type Hamiltonian, can be efficiently maneuvered to speed up a given state transformation in a highly adiabatic manner and with a low energy cost

    Routine immunofluorescent and histochemical analysis of bone marrow involvement of lymphoma/leukaemia: the use of cryostat sections.

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    Enzyme histochemical and immunohistological (immuno-fluorescence and -peroxidase) techniques have been routinely used for investigating over 70 normal and pathological bone marrow samples. This recently standardized diagnostic procedure is very quick and can be performed in a few hours. In 6 cases the clinical diagnosis of leukaemia/lymphoma has become apparent only after the immunohistological analysis of the bone marrow. In 6 other cases the information about the staging of B cell malignancies was superior in the frozen biopsies to the paraffin embedded preparations. Amongst many other features the monoclonality of B CLL/lymphomas, the special features of B CLL infiltrates (RFA-1+, Leu-1+, HLA-DR+, SmIg+), follicular lymphoma deposits (containing follicular dendritic cells) and non-T, non-B acute lymphoblastic leukaemic blasts (terminal transferase+, HLA-DR+) as well as the sometimes conspicuous presence of infiltrating normal T cells could be clearly and reproducibly demonstrated

    A Doubly Nudged Elastic Band Method for Finding Transition States

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    A modification of the nudged elastic band (NEB) method is presented that enables stable optimisations to be run using both the limited-memory quasi-Newton (L-BFGS) and slow-response quenched velocity Verlet (SQVV) minimisers. The performance of this new `doubly nudged' DNEB method is analysed in conjunction with both minimisers and compared with previous NEB formulations. We find that the fastest DNEB approach (DNEB/L-BFGS) can be quicker by up to two orders of magnitude. Applications to permutational rearrangements of the seven-atom Lennard-Jones cluster (LJ7) and highly cooperative rearrangements of LJ38 and LJ75 are presented. We also outline an updated algorithm for constructing complicated multi-step pathways using successive DNEB runs.Comment: 13 pages, 8 figures, 2 table

    Newly described human polyomaviruses Merkel Cell, KI and WU are present in urban sewage and may represent potential environmental contaminants

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    Recently, three new polyomaviruses (KI, WU and Merkel cell polyomavirus) have been reported to infect humans. It has also been suggested that lymphotropic polyomavirus, a virus of simian origin, infects humans. KI and WU polyomaviruses have been detected mainly in specimens from the respiratory tract while Merkel cell polyomavirus has been described in a very high percentage of Merkel cell carcinomas. The distribution, excretion level and transmission routes of these viruses remain unknown

    Comparative study of Spanish norms used to quantify gypsum content in civil and building construction

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    The "Pliego de Prescripciones Técnicas Generales para Obras de Carreteras y Puentes (PG3)" is the Spanish's Government Technical Instruction that stablishes the properties that materials used in road and bridge construction must accomplish, and includes the corresponding standardized norms to test these properties

    Systematic Detection of Anomalous Ionospheric Perturbations Above LEOs From GNSS POD Data Including Possible Tsunami Signatures

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    In this article, we show the capability of a global navigation satellite system (GNSS) precise orbit determination (POD) low Earth orbit (LEO) data to detect anomalous ionospheric disturbances in the spectral range of the signals associated with earthquakes and tsunamis, applied to two of these events in Papua New Guinea (PNG) and the Solomon Islands during 2016. This is achieved thanks to the new PIES approach (POD-GNSS LEO Detrended Ionospheric Electron Content Significant Deviations). The significance of such ionospheric signals above the swarm LEOs is confirmed with different types of independent data: in situ electron density measurements provided by the Langmuir Probe (LP) onboard swarm LEOs, DORIS, and ground-based GNSS colocated measurements, as it is described in this article. In this way, we conclude the possible detection of the tsunami-related ionospheric gravity wave in PNG 2016 event, consistent with the most-recent theory, which shows that a tsunami (which is localized in space and time) excites a spectrum of gravity waves, some of which have faster horizontal phase speeds than the tsunami. We believe that this work shows as well the feasibility of a future potential monitoring system of ionospheric disturbances, to be made possible by hundreds of CubeSats with POD GNSS receivers among other appropriate sensors, and supported for real-time or near real-time confirmation and characterization by thousands of worldwide existing ground GNSS receivers

    Standardising outcome reporting for clinical trials of interventions for heavy menstrual bleeding: Development of a core outcome set

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    OBJECTIVE: To develop a core outcome set for heavy menstrual bleeding (HMB). DESIGN: Core outcome set (COS) development methodology described by the COMET initiative. SETTING: University hospital gynaecology department, online international survey and web-based international consensus meetings. POPULATION OR SAMPLE: Phase 1: Systematic review of previously reported outcomes to identify potential core outcomes. Phase 2: Qualitative studies with patients to identify outcomes most important to them. Phase 3: Online two-round Delphi survey to achieve consensus about which outcomes are most important. Phase 4: A consensus meeting to finalise the COS. METHODS: Phase 1: Systematic review of previously reported outcomes to identify potential core outcomes. Phase 2: Qualitative studies with patients to identify outcomes most important to them. Phase 3: Online two-round Delphi survey to achieve consensus about which outcomes are most important. Phase 4: A consensus meeting to finalise the COS. MAIN OUTCOME MEASURES: Outcome importance was assessed in the Delphi survey on a 9-point scale. RESULTS: From the ‘long list’ of 114, 10 outcomes were included in the final COS: subjective blood loss; flooding; menstrual cycle metrics; severity of dysmenorrhoea; number of days with dysmenorrhoea; quality of life; adverse events; patient satisfaction; number of patients going on to have further treatment for HMB and haemoglobin level. CONCLUSIONS: The final COS includes variables that are feasible for use in clinical trials in all resource settings and apply to all known underlying causes of the symptom of HMB. These outcomes should be reported in all future trials of interventions, their systematic reviews, and clinical guidelines to underpin policy
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