Clinical signs, aetiology and outcome in 30 cats with recurrent seizures (2002-2018)

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗThe purpose of the current study was to describe seizure types, aetiology, treatment response and outcome in 30cats with recurrent seizures. This retrospective case series study included the medical records of client-owned cats, admitted to the Clinic of Companion Animals for seizure disorders, from 2002 to 2018. Recorded data included history, seizure type, physical and neurological examination findings, blood pressure measurements, complete blood counts, serum biochemistry profile and urinalysis, tentative/final diagnosis, treatment, hospitalization and longterm outcome. A total of 298 feline neurology cases were examined during the study period. Of those, 38 cases were admitted for seizure disorders and 30 met the inclusion criteria. Median age on admission was 38,2 months (3,1 years) (range 2 months- 14 years old).Seizure types, as per owner description, were generalized (26 cats), focal with secondary generalization (3 cats), focal (2 cats) and complex (1 cat). Cluster seizures appeared at least once in 18/30 and status epilepticus in 7/30. Different seizure types were also recorded in individual cases. Fifteen cats (15/30) were hospitalized at least once and the duration of hospitalization ranged from 1-10 days. In most cases, in which diagnosis was established, epilepsy wassecondary (25/30), due to previous head trauma(11/30),metabolic (1/30), or inflammatory (4/30) disease, arterial hypertension (3/30), toxicosis (3/30) and intracranial neoplasia (2/30).Congenital hydrocephalus was detected in 1 cat. Tentative diagnosis could not be established in 5cats; however differential diagnosis included inflammatory or neoplastic encephalopathies.Antiepileptic drug monotherapy (phenobarbital or levetiracetam) was sufficient to control the seizures in 14 cases, while administration of combination therapy with 2 or more antiepileptic drugs was required in 5 cases (phenobarbital, levetiracetam, gabapentin). Successful control was achieved in 11/30 animals for 1-5 years. Seven cats required intensive care at least once due to status epilepticus. Until today, eighteen (18/30) cats are still alive and 11 died or were euthanized.Although in most cases epilepsy was secondary, seizure control was adequate and quality of life (QoL) was improved with antiepileptic drugs when metabolic, inflammatory and neoplastic encephalopathies were excluded.

A szlovákiai magyar irodalomtanítás legújabb perspektívái

A szlovákiai magyar iskolákban 2015 szeptemberétől lépett érvénybe a revideált oktatási program, mely az irodalomtanítást radikálisan új lehetőségek mentén teszi kibontakoztathatóvá. „A [korábbi] rendszer egy szikrányi érdeklődést sem mutat[ott] a diákok valódi igényei és érdeklődése iránt. A tanárnak úgy kell[ett] becsempésznie a szövegeket az órára, hogy közben azt kockáztat[t]a, hogy »lemarad« a tananyaggal. Az irodalmi szövegek nélkül viszont az óra unalmas, kreativitást és önállóságot nélkülöző, elpazarolt lehetőséggé válik” – írja meghatározó munkájában Hegedűs Norbert (2014, 56. o.). Lehet tenni bármit ez ellen? Munkánk többek között erre a kérdésre keresi a választ, kardinális empirikus kutatások eredményeire alapozva megállapításait, ajánlatait és kifutási projektjét. Első szakaszában a magyarországi, romániai magyar és a korábbi szlovákiai magyar oktatási programokat ütközteti a 2015-től hatályos revideált oktatási program lehetőségeivel, ezt követően néhány új irodalomtanítási alternatívát vázol, majd a kanonizált és kötelező olvasmányok listáját a diákok olvasói érdeklődésének és kívánalmainak tükrében értékeli, nem csak szlovákiai magyar viszonylatban. Zárásként a legújabb irodalomtudományi eredményekkel megtámogatott, értékes populáris irodalomról értekezik, minek révén a literatúra újra a tanulók érdeklődésének fókuszába kerülhet

NIRS PREDICTION FOR PROTEIN AND INTRAMUSCULAR FAT CONTENT OF RABBIT HIND LEG MEAT

The goal of this study was to develop calibration equations to predict the chemical composition of raw, homogenized rabbit meat by means of near infrared spectroscopy (NIRS). 44 Pannon White rabbits were housed in groups in three different pen types (16 anim./m2), and were fed the same diet. Another 45 animals were housed in cages (12 anim./m2) and fed by different feeding regimes. Rabbits were slaughtered at the bodyweight of 2.4-2.5 kg. Homogenized fresh and freeze-dried left total hind leg muscles were investigated by NIRS using a NIRSystem 6500 equipment with small ring cup sample holder. The ether extract and protein content of all samples were determined chemically. Samples 44 of housing experiment were applied in producing LOCAL calibration equations tested on the 45 samples from the separate feeding experiment. Coefficients of determination (R2) of the predictions were 0.89 and 0.99 for fat, 0.85 and 0.96 for protein in fresh and freeze-dried samples, respectively. Results are reassuring, because the equations were applicable, however the analyzed samples were from independent housing and feeding systems. Therefore the chemical compositions differed in the two datasets, i.e. 9.46%, and 11.79% for fat, 85.75% and 83.44% for protein content in calibration and prediction datasets, respectively. The average of NIRS predicted values for fat and protein was 11.36%, 83.88% or 11.54%, 83.45% when using fresh or freeze-dried samples, respectively

The role of menaquinones (vitamin K2) in human health

Recent reports have attributed the potential health benefits of vitamin K beyond its function to activate hepatic coagulation factors. Moreover, several studies have suggested that menaquinones, also known as vitamin K2, may be more effective in activating extra-hepatic vitamin K-dependent proteins than phylloquinone, also known as vitamin K1. Nevertheless, present dietary reference values (DRV) for vitamin K are exclusively based on phylloquinone, and its function in coagulation. The present review describes the current knowledge on menaquinones based on the following criteria for setting DRV: optimal dietary intake; nutrient amount required to prevent deficiency, maintain optimal body stores and/or prevent chronic disease; factors influencing requirements such as absorption, metabolism, age and sex. Dietary intake of menaquinones accounts for up to 25% of total vitamin K intake and contributes to the biological functions of vitamin K. However, menaquinones are different from phylloquinone with respect to their chemical structure and pharmacokinetics, which affects bioavailability, metabolism and perhaps impact on health outcomes. There are significant gaps in the current knowledge on menaquinones based on the criteria for setting DRV. Therefore, we conclude that further investigations are needed to establish how differences among the vitamin K forms may influence tissue specificities and their role in human health. However, there is merit for considering both menaquinones and phylloquinone when developing future recommendations for vitamin K intak

The Impact of the Gold Mining on the Social, Economic, Andcultural in the Bombana District Southeast Sulawesi Province

The phenomenon of a gold mine brings a lot of changes in people's daily life in the Bombana District. This study aims to: (a) Aware of the social and cultural changes in society before and after the gold mining business, and (b) Knowing the changes in people's income before and after the gold mining business. The study population is the people who are in the gold mining sites. This study result, namely: (a) Gold mining have negative impact on social, economic, and cultural of communities around the gold mining area. Social, economic, and cultural societies tend to be in better shape before the gold mining. Average income communities after the gold mining increase by Rp 755.392 per month. (c) Gold mining do not increase the welfare of society, especially for farmers. The implication of this study is the government should strictly supervise and tighten even a moratorium against IUP, and gold mining companies should have corporate social responsibility (CSR) in the form of incentives to the affected communities of the businesses under their management in the fields of education, health, agriculture, economics, and culture as well as other aspects relating to the welfare of society

APPLICABILITY OF THE TOBEC METHOD IN SELECTION OF HEN’S EGGS BASED ON THEIR COMPOSITION

Applicability of the TOBEC method (electrical conductivity) was tested for the in vivo determination of different egg components and for the separation of eggs with different composition. Altogether 300 hen’s eggs – originated from a 36 weeks old ROSS-308 hybrid parent stock – were measured by TOBEC, and the extreme and average 5-5% – based on the measured values – were chosen for chemical analysis. It was established that the albumen/yolk ratio and the dry matter, crude protein and crude fat content of the eggs are in medium correlation with the E-value/egg weight ratio (r=0.47, -0.58, -0.59 and -0.35 respectively). The albumen/yolk ratio, the dry matter and the crude protein content of the eggs, selected for high and low E-value/egg weight ratio, differed significantly at P<0.05 level. The difference between the average crude fat content of the eggs in the two extreme groups was significant at P<0.10 level