Communication and crisis in the public space: Dissolution and uncertainty

The evolution from a public space such as the one defined throughout the twentieth century –characterised by unidirectionality and political and media intermediation– towards a digital scenario –with multiple actors and multi-directional messages– has not resolved the problems that existed beforehand, and has also generated others. This public space crisis has been aggravated by the fragmentation of audiences, often absorbed into their own echo chamber, and by the dispersion and jumble of voices that are an impediment to any possibility of unravelling the terms of public debate. Faced with enormous challenges such as disinformation, the conventional media, who have traditionally held the responsibility of providing quality information, address these issues from a position of extreme vulnerability, due to the disintegration of the former economic model and social credibility. In a context of uncertainty, crisis, and fragmented public spheres, and there being no alternatives that can guarantee distinct dialogue, the initiation of a social debate that prioritises quality of information is essential.&nbsp

Dimensionamiento de transformadores de distribución con base al efecto de los armónicos

El presente trabajo tiene como objetivo hacer una revisión bibliográfica acerca de la distorsión armónica, uno de los problemas que más afecta las redes de distribución de energía eléctrica, ya que altera los ciclos de vida de los elementos pertenecientes al sistema y perturba su buen funcionamiento. Las señales armónicas son múltiplos integrales de la frecuencia fundamental de una onda sinusoidal, generadas por cargas no lineales, estas se suman a la onda fundamental de 60-, lo que provoca distorsiones en la onda. Por tal motivo se llevó a cabo un estudio sobre las fuentes generadoras de armónicos y sus efectos en diferentes cargas eléctricas presentes comúnmente en instalaciones residenciales y comerciales. En específico se estudió el comportamiento de los transformadores pertenecientes a las redes de distribución, bajo el efecto de los armónicos y su respectivo dimensionamiento para prevenir los daños causados por la distorsión. Se finalizó con el estudio del dimensionamiento del transformador en presencia de armónicos, referenciándolo al modo de construcción utilizado por ABB Transformadores, definiendo las características de diseño y los materiales indicados en su construcción, con el fin de reducir los efectos causados por estas perturbaciones para mantener el rango de vida útil predefinida y así disminuir los daños ocasionados dentro del a red

The hot core towards the intermediate mass protostar NGC7129 FIRS 2: Chemical similarities with Orion KL

NGC 7129 FIRS 2 (hereafter FIRS 2) is an intermediate-mass (2 to 8 Msun) protostar located at a distance of 1250 pc. High spatial resolution observations are required to resolve the hot core at its center. We present a molecular survey from 218200 MHz to 221800 MHz carried out with the IRAM Plateau de Bure Interferometer. These observations were complemented with a long integration single-dish spectrum taken with the IRAM 30m telescope. We used a Local Thermodynamic Equilibrium (LTE) single temperature code to model the whole dataset. The interferometric spectrum is crowded with a total of ~300 lines from which a few dozens remain unidentified yet. The spectrum has been modeled with a total of 20 species and their isomers, isotopologues and deuterated compounds. Complex molecules like methyl formate (CH3OCHO), ethanol (CH3CH2OH), glycolaldehyde (CH2OHCHO), acetone (CH3COCH3), dimethyl ether (CH3OCH3), ethyl cyanide (CH3CH2CN) and the aGg' conformer of ethylene glycol (aGg'-(CH2OH)_2) are among the detected species. The detection of vibrationally excited lines of CH3CN, CH3OCHO, CH3OH, OCS, HC3N and CH3CHO proves the existence of gas and dust at high temperatures. In fact, the gas kinetic temperature estimated from the vibrational lines of CH3CN, ~405 K, is similar to that measured in massive hot cores. Our data allow an extensive comparison of the chemistry in FIRS~2 and the Orion hot core. We find a quite similar chemistry in FIRS 2 and Orion. Most of the studied fractional molecular abundances agree within a factor of 5. Larger differences are only found for the deuterated compounds D2CO and CH2DOH and a few molecules (CH3CH2CN, SO2, HNCO and CH3CHO). Since the physical conditions are similar in both hot cores, only different initial conditions (warmer pre-collapse phase in the case of Orion) and/or different crossing time of the gas in the hot core can explain this behavior.Comment: 30 pages, 9 figure

Improving the efficacy of exposure therapy using projection-based augmented reality for the treatment of cockroach phobia: a randomised clinical trial protocol

Introduction: In vivo exposure is the treatment of choice for specific phobia (SP), but this technique presents limitations related to access and acceptability. Augmented reality (AR) offers advantages like maximising strategies such as ‘variability’ (varying stimuli, durations, levels of intensity or the order of the items), control by the therapist, or ‘exposure to multiple contexts’, which can produce positive effects in terms of fear renewal and generalisation of the results. The aim of this study is to test the efficacy of varying the phobic stimuli during treatment with AR: using multiple stimuli (MS) versus a single stimulus (SS) in participants with SP. Methods and analysis: Participants (N=80) with a diagnosis of an SP of cockroaches will be randomised into two conditions: (1) projection-based AR exposure therapy with MS (P-ARET MS); (2) P-ARET with an SS (P-ARET SS). The measures are related to the efficacy results (fear, avoidance and negative thoughts, performance on the behavioural avoidance test (BAT) and preferences). The primary outcome measure is the BAT, and the secondary outcome measures are the BAT through AR, Fear of Cockroaches Questionnaire, Cockroach Phobia Beliefs Questionnaire, Fear and Avoidance Scales Patient’s Improvement Scale, and Beck Depression Inventory Second Edition. Five evaluation moments will be included: preintervention, postintervention, and 1-month, 6-month, and 12-month follow-ups. The treatment will follow the guidelines of the ‘one-session treatment’. Student’s t-tests to compare the two groups on the post-test will be applied. In addition, two-way analysis of variances with repeated measures in one of the two factors (pretest, post-test and follow-ups) will be carried out to compare intragroup differences. Ethics and dissemination: The Universitat Jaume I Ethics Committee (Castellón, Spain) granted approval for the study (CD/64/2019). Dissemination will include publications and presentations at national and international conferences

Effectiveness of a projection-based augmented reality exposure system in treating cockroach phobia: study protocol of a randomised controlled trial

Background: Despite being the treatment of choice for phobic disorders, in vivo exposure treatment (IVET) presents some important limitations related mainly to low acceptance and high drop-out rates. Augmented reality (AR) technologies can help to overcome these limitations. Evidence supports the use of AR in exposure treatment for small animal phobia. A new projection-based AR exposure treatment system (P-ARET) that offers the possibility of projecting the animals in a natural and non-intrusive environment has been developed. There are no randomised controlled trials (RCTs) available that have tested the efficacy of this system in cockroach phobia. This paper aims to present the protocol of an RCT that evaluates the efficacy of the P-ARET, versus an IVET group and a waiting list control group (WL), in carrying out exposure treatment for cockroach phobia. Methods/design: Participants will be randomly allocated to one of three conditions: (1) P-ARET, (2) IVET and (3) WL. Both treatment conditions will follow the ‘one-session treatment’ guidelines. As a diagnostic measure, the Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual for Mental Health Disorders-Version 5 will be used. The Behavioral Avoidance Test will be used as the primary outcome measure. Secondary outcome measures will include an attentional biases task (measured using eye-tracking technology), the Fear of Cockroaches Questionnaire, Cockroach Phobia Beliefs Questionnaire, Fear and Avoidance Scales, Beck Depression Inventory second edition, Disgust Propensity and Sensitivity Scale-Revised-12, State-Trait Anxiety Inventory, Clinician Severity Scale, and Expectation and Satisfaction with the Treatment Scale. The evaluation protocol will include pretreatment and post-treatment evaluations and 1, 6 and 12 months of follow-ups. Intention-to-treat and per-protocol analyses will be performed. Ethics and dissemination: This study has been approved by the Ethics Committee of Universitat Jaume I (Castellón, Spain; 13 December 2019). The results of the presented RCT will be disseminated in presentations at international scientific meetings and peer-reviewed scientific journals.Funding for the study was provided by Grant Ministerio de Ciencia, Innovación y Universidades (Spain) (Programa Estatal I+D+I) (grant number: RTI2018-100993-B-100) funded by MCIN/AEI/10.13039/501100011033 and by 'ERDF A way of making Europe', by the European Union.Funding for the study was provided by Grant Ministerio de Ciencia, Innovación y Universidades (Spain) (Programa Estatal I+D+i RTI2018-100993-B-100) funded by MCIN/AEI/ 10.13039/501100011033 and by 'ERDF A way of making Europe', by the 'European Union'

Portal Web para la gestión de Ayuntamientos

La finalidad principal del proyecto es mediante este portal, acercar a la población toda la información referente a la localidad y el ayuntamiento, así como aumentar la capacidad de interacción con la aplicación por parte del usuario. La nueva aplicación dispondrá de 3 perfiles de usuario junto con una serie de características acerca de sus funcionalidades que tendrá a su disposición. 1- Usuario Administrador: personal del ayuntamiento encargada de realizar las gestiones de las distintas funcionalidades que tendrá el portal, como por ejemplo: crear, eliminar y editar. 2- Usuario Interino: El rol que cumple es el propio de un funcionario del ayuntamiento, es decir, dispondrá de una interfaz dedicada con el objetivo de gestionar los contenidos de una parte del portal. 3- Usuario Registrado: será aquella persona que previamente haya completado el formulario de registro satisfactoriamente y se haya autentificado en el portal. Tendrá una serie de privilegios que no dispondrá un usuario anónimo, como por ejemplo: realizar reservas de las instalaciones deportivas.Francés López, JM.; Palau Arnau, V. (2012). Portal Web para la gestión de Ayuntamientos. http://hdl.handle.net/10251/17587.Archivo delegad

Nivelación hidrostática entre dos mareógrafos situados en el Puerto de Barcelona

Este estudio pretende relacionar los registros (marzo de 2013 a febrero de 2014) de dos mareógrafos situados en el Puerto de Barcelona y que se han denominado BCN2 y BCN3. El mareógrafo BCN2 pertenece a la RED de MAReógrafos de Puertos del Estado (REDMAR) y refiere los datos al NMMA1995 mientras que BCN3, propiedad de la Autoridad Portuaria de Barcelona, los refiere a la Red Topográfica del Puerto de Barcelona observada mediante técnicas GNSS. Ambos mareógrafos están separados unos 3Km. en línea recta y unos 8Km. por tierra. El objetivo ha sido determinar la diferencia existente entre los ceros de referencia de los dos mareógrafos. El nivel de mar observado por los mareógrafos, sin tener en cuenta la acción del oleaje, está afectado por la marea astronómica y la marea meteorológica. La marea meteorológica es de tipo aleatorio, por el contrario la marea astronómica es de carácter determinista y se puede resolver realizando el análisis de armónicos. Para ello, una vez realizado el control de calidad de los datos brutos, se utilizó la aplicación T_TIDE en MATLAB obteniendo como resultado para cada mareógrafo tres gráficas y dos ficheros. Las gráficas representan respectivamente el nivel del mar observado, la marea astronómica y la meteorológica o residuo y de los dos ficheros, uno corresponde al cálculo de los componentes armónicos, del que nos interesa la componente Z0 (nivel medio del mar) y el segundo contiene la componente meteorológica. Se puede concluir en que el cero de referencia de BCN3 está situado 0,096 metros por encima del NMMA 1995.Peer ReviewedPostprint (published version

Intraorganellar acidification by V-ATPases: a target in cellproliferation and cancer therapy

V-ATPases are multicomponent proton pumps involved in the acidification of singlemembrane intracellular compartments such as endosomes and lysosomes. They couple thehydrolysis of ATP to the translocation of one to two protons across the membrane. Acidification ofthe lumen of single membrane organelles is a necessary factor for the correct traffic of membranesand cargo to and from the different internal compartments of a cell. Also, V-ATPases are involved inregulation of pH at the cytosol and, possibly, extracellular milieu. The inhibition of V-ATPases hasbeen shown to induce apoptosis and cell cycle arrest in tumour cells and, therefore, chemicals thatbehave as inhibitors of this kind of proton pumps have been proposed as putative treatment agentsagainst cancer. The present review will summarize the major types of V-ATPase inhibitors and theirmechanisms of action and put them in relation to the patents registered so far for the treatment of cancer.Junta de Andalucía PAIDI BIO-261 P07-CVI-3082Ministerio de Ciencia e Innovación BMC2007-6188

Design and Development of an AIoT Architecture for Introducing a Vessel ETA Cognitive Service in a Legacy Port Management Solution

[EN] Current Internet of Things (IoT) stacks are frequently focused on handling an increasing volume of data that require a sophisticated interpretation through analytics to improve decision making and thus generate business value. In this paper, a cognitive IoT architecture based on FIWARE IoT principles is presented. The architecture incorporates a new cognitive component that enables the incorporation of intelligent services to the FIWARE framework, allowing to modernize IoT infrastructures with Artificial Intelligence (AI) technologies. This allows to extend the effective life of the legacy system, using existing assets and reducing costs. Using the architecture, a cognitive service capable of predicting with high accuracy the vessel port arrival is developed and integrated in a legacy sea traffic management solution. The cognitive service uses automatic identification system (AIS) and maritime oceanographic data to predict time of arrival of ships. The validation has been carried out using the port of Valencia. The results indicate that the incorporation of AI into the legacy system allows to predict the arrival time with higher accuracy, thus improving the efficiency of port operations. Moreover, the architecture is generic, allowing an easy integration of the cognitive services in other domains.Funding This work has been developed under the framework of the COSIBAS project (funded by CDTI research and innovation programme under grant agreement No.EXP 00110912/INNO-20181033) and the EIFFEL project (funded by European Unions Horizon 2020 research and innovation programme under grant agreement No 101003518).Valero López, CI.; Ivancos Pla, E.; Vañó García, R.; Garro, E.; Boronat, F.; Palau Salvador, CE. (2021). Design and Development of an AIoT Architecture for Introducing a Vessel ETA Cognitive Service in a Legacy Port Management Solution. Sensors. 21(23):1-15. https://doi.org/10.3390/s21238133115212

Stereoselective Alkylation of Chiral Titanium(IV) Enolates with tert-Butyl Peresters

[EN]Here, we present a new stereoselective alkylation of titanium(IV) enolates of chiral N-acyl oxazolidinones with tert-butyl peresters from Calpha-branched aliphatic carboxylic acids, which proceeds through the decarboxylation of the peresters and the subsequent formation of alkyl radicals to produce the alkylated adducts with an excellent diastereoselectivity. Theoretical calculations account for the observed reactivity and the outstanding stereocontrol. Importantly, the resultant compounds can be easily converted into ligands for asymmetric and catalytic transformations.We acknowledge financial support from the Spanish Ministerio de Ciencia, e Innovación (MCIN)/Agencia Estatal de Investigación (AEI)/Fondo Europeo de Desarrollo Regional (FEDER, UE) (Grant No. PGC2018-094311-B-I00 and Grant No. PID2019-110008GB-I00), the Generalitat de Catalunya (2017SGR 271), and SGIker (UPV/EHU) for providing human and computational resources. Furthermore, a doctorate studentship to M.P.-P. (FPU, MINU) is acknowledged