Análisis del electrocardiograma en pacientes con infarto agudo de miocardio anterior: correlación con desarrollo de disfunción ventricular izquierda, eventos cardiovasculares a largo plazo y biomarcadores

Tesis Doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Medicina. Fecha de Lectura: 28-06-202

La langue de la Segunda partida : Comprendre pour traduire et traduire pour comprendre

La traduction française de la Segunda partida d’Alphonse X à laquelle nous participons dans le cadre du SIREM nous a amenées à un questionnement linguistique pour et par la traduction. Cet article recueille quelques-unes de ces réflexions. L’étude des conjonctions maguer et comoquier que, dans l’optique de leur traduction en français, nous conduit à nous interroger sur la valeur de ces deux conjonctions et de l’alternance modale dans les phrases concessives qu’elles introduisent. Nous proposons une typologie des phrases concessives, et notamment la distinction entre concessives d’énoncé et concessives d’énonciation pour rendre compte de leurs différences dans le texte de la Segunda partida. Dans la partie « traduire pour comprendre » nous étudions un phénomène difficilement appréciable depuis une perspective monolingue : la puissance anaphorique du pronom personnel objet de 3e personne supérieure en castillan médiéval, comparable à celle d’un démonstratif – phénomène et qui est en accord avec la description théorique qui a été faite de l’histoire du pronom atone comme un processus de grammaticalisation.<br>La versión al francés de la Segunda partida de Alfonso X en la que participamos en el marco del SIREM nos ha conducido a un cuestionamiento lingüístico para y por la traducción. Este artículo recoge algunas de estas reflexiones. La necesidad de traducir al francés las conjunciones maguer y comoquier que nos ha llevado a interesarnos por el valor de estas dos conjunciones y de la alternancia modal en las oraciones concesivas que ambas introducen. Proponemos aquí una tipología de las oraciones concesivas y en particular, la distinción entre concesivas de enunciado y concesivas de enunciación para dar cuenta de sus diferencias en el texto de la Segunda partida. En la parte « traducir para comprender », estudiamos un fenómeno difícilmente apreciable desde una perspectiva monolingüe: una potencia anafórica del pronombre personal objeto de tercera persona superior en castellano medieval, comparable a la de un demostrativo – un fenómeno que encaja en la descripción teórica que se ha hecho de la historia del pronombre átono como un proceso de gramaticalización

Essential Mineral Content (Fe, Mg, P, Mn, K, Ca, and Na) in Five Wild Edible Species of Lactarius Mushrooms from Southern Spain and Northern Morocco: Reference to Daily Intake

Mushroom consumption has increased in recent years due to their beneficial properties to the proper functioning of the body. Within this framework, the high potential of mushrooms as a source of essential elements has been reported. Therefore, the present study aims to determine the mineral content of seven essential metals, Fe, Mg, Mn, P, K, Ca, and Na, in twenty samples of mushrooms of the genus Lactarius collected from various locations in southern Spain and northern Morocco, by FAAS, UV-Vis spectroscopy, and ICP-OES after acid digestion. Statistics showed that K was the macronutrient found at the highest levels in all mushrooms studied. ANOVA showed that there were statistically significant differences among the species for K, P, and Na. The multivariate study suggested that there were differences between the accumulation of the elements according to the geographic location and species. Furthermore, the intake of 300 g of fresh mushrooms of each sample covers a high percentage of the RDI, but does not meet the recommended daily intake (RDI) for any of the metals studied, except for Fe. Even considering these benefits, the consumption of mushrooms should be moderated due to the presence of toxic metals, which may pose health risks.16 página

Aspectos motivacionales, autoconcepto físico y percepción de competencia en Educación Física en el alumnado de 1º de Educación Secundaria Obligatoria

El presente estudio tiene por objeto conocer el autoconcepto físico y por lo tanto la percepción de competencia, así como, la motivación de los alumnos de 1º de Educación Secundaria Obligatoria (ESO) en las clases de Educación Física (EF), diferenciando según el género. La muestra fue de 90 alumnos (49 chicas y 41 chicos) de edades comprendidas entre los 12 y 14 años del instituto I.E.S Ramón y Cajal de Huesca. Los instrumentos utilizados fueron el Cuestionario de Motivación en las Clases de EF (CMEF) y el Cuestionario Physical-Self Description (PSDQ). Los resultados muestran mejores valores del género femenino frente al género masculino con diferencias significativas en determinados valores de autoconcepto físico y motivación en las clases de EF.<br /

Toxic elements and trace elements in Macrolepiota procera mushrooms from southern Spain and northern Morocco

Anthropogenic activities, such as mining and fossil fuel combustion, produce large amounts of pollutants that affect environmental homeostasis. Wild edible mushrooms fructify exposed to environmental conditions, proving to be efficient accumulators of trace elements and toxic and potentially toxic elements. Due to the increasing consumption of mushrooms worldwide, this is of public health concern. In this work, the total content of chromium (Cr), arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb), copper (Cu), zinc (Zn), and selenium (Se) was determined by ICP-MS in the caps and stipes of the high valued wild edible mushroom Macrolepiota procera collected in several locations of the South of Spain and the North of Morocco. The results obtained have indicated that the cap of M. procera contains a broad spectrum of both toxic elements and trace elements, occurring in higher contents in this part of the fruiting body with respect to the stipe. Moreover, Cu was the predominant element found in the samples studied, followed by Zn in most of the cases. The one-way ANOVA/Kruskal-Wallis test indicated that there were no significant differences in metal and metalloid content between the geographical areas studied. In addition, the results obtained through Hierarchical Cluster Analysis (HCA) and Principal Component Analysis (PCA) support the conclusions drawn through univariate statistical studies, indicating that there is no obvious clustering trend for the M. procera cap samples based on the sampling area. The health risk assessment for M. procera caps showed a cause for concern related to Cr, Cd, As, and Hg due to frequent consumption of around 300 g of fresh caps per day during the mushrooming season. © 2022 The Author(s

Exposure to Essential and Toxic Elements via Consumption of Agaricaceae, Amanitaceae, Boletaceae, and Russulaceae Mushrooms from Southern Spain and Northern Morocco

The demand and interest in mushrooms, both cultivated and wild, has increased among consumers in recent years due to a better understanding of the benefits of this food. However, the ability of wild edible mushrooms to accumulate essential and toxic elements is well documented. In this study, a total of eight metallic elements and metalloids (chromium (Cr), arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb), copper (Cu), zinc (Zn), and selenium (Se)) were determined by ICP-MS in five wild edible mushroom species (Agaricus silvicola, Amanita caesarea, Boletus aereus, Boletus edulis, and Russula cyanoxantha) collected in southern Spain and northern Morocco. Overall, Zn was found to be the predominant element among the studied species, followed by Cu and Se. The multivariate analysis suggested that considerable differences exist in the uptake of the essential and toxic elements determined, linked to species-intrinsic factors. Furthermore, the highest Estimated Daily Intake of Metals (EDIM) values obtained were observed for Zn. The Health Risk Index (HRI) assessment for all the mushroom species studied showed a Hg-related cause of concern due to the frequent consumption of around 300 g of fresh mushrooms per day during the mushrooming season

Ozenoxacin: a review of preclinical and clinical efficacy

Introduction: Impetigo is the most common bacterial skin infection in children. Treatment is becoming complicated due to the development of antimicrobial resistance, especially in the main pathogen, Staphylococcus aureus. Ozenoxacin, a novel non-fluorinated topical quinolone antimicrobial, has demonstrated efficacy in impetigo. Areas covered: This article reviews the microbiology, pharmacodynamic and pharmacokinetic properties of ozenoxacin, and its clinical and microbiological efficacy in impetigo. Expert opinion: In an environment of increasing antimicrobial resistance and concurrent slowdown in antimicrobial development, the introduction of a new agent is a major event. Ozenoxacin is characterized by simultaneous affinity for DNA gyrase and topoisomerase IV, appears to be impervious to certain efflux pumps that confer bacterial resistance to other quinolones, shows low selection of resistant mutants, and has a mutant prevention concentration below its concentration in skin. These mechanisms protect ozenoxacin against development of resistance, while the absence of a fluorine atom in its structure confers a better safety profile versus fluoroquinolones. In vitro studies have demonstrated high potency of ozenoxacin against staphylococci and streptococci including resistant strains of S. aureus. Clinical trials of ozenoxacin in patients with impetigo reported high clinical and microbiological success rates. Preserving the activity and availability of ozenoxacin through antimicrobial stewardship is paramount

Evaluation of organic, conventional and intensive beef farm systems: health, management and animal production

The overall aim of the present study was to analyse and compare organic beef cattle farming in Spain with intensive and conventional systems. An on-farm study comparing farm management practices and animal health was carried out. The study also focussed on a slaughterhouse analysis by comparing impacts on the safety and quality of the cattle products. Twenty-four organic and 26 conventional farms were inspected, and farmers responded to a questionnaire that covered all basic data on their husbandry practices, farm management, veterinary treatments and reproductive performance during 2007. Furthermore, data on the hygiene and quality of 244, 2596 and 3021 carcasses of calves from organic, intensive and conventional farms, respectively, were retrieved from the official yearbook (2007) of a slaughterhouse. Differences found between organic and conventional farms across the farm analysis did not substantially reflect differences between both farm types in the predominant diseases that usually occur on beef cattle farms. However, calves reared organically presented fewer condemnations at slaughter compared with intensive and to a lesser extent with conventionally reared calves. Carcass performance also reflected differences between farm type and breed and was not necessarily better in organic farmsThis study was supported by the Xunta de Galicia (Spain;PGIDT02RA6261001PR) and I.B.P. received a research fellow-ship (AP2003-3835) from the Ministry of Science of SpainS