73 research outputs found

    Apuntes para una metafísica elemental

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    T. I: Metafísica general y cosmología (438 p.) -- T. II: Psicología y Teodicea (358 p.)Copia digital. España : Ministerio de Cultura y Deporte. Subdirección General de Coordinación Bibliotecaria, 2020Se deduce impreso probablemente ca. 1896-1900 por citar en el prólogo la fecha de 1892 como de cuatro años ante

    Impact of hospitalization on nutritional status in persons aged 65 years and over (NUTRIFRAG Study): Protocol for a prospective observational study

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    [ES] Background Malnutrition is a recurring problem that has become more relevant in recent years. The aim of this study is to assess the risk of malnutrition and nutritional status on admission and its evolution until discharge in patients aged 65 and over admitted to medical and surgical hospitalization units in hospitals of the Spanish National Health System. Methods Prospective observational study to be carried out in the medical-surgical hospitalization units of 9 public hospitals between 01/09/2022 and 31/12/2024. Using consecutive sampling, a total of 4077 patients will be included (453 in each hospital). Variables included are related to the care process, functionality, cognition and comorbidity, risk profile, nutritional status and dysphagia; as well as frailty, dietary quality and contextual variables. The incidence of risk of malnutrition, undernutrition and dysphagia during the care process and at discharge will be calculated. The association with risk factors will be studied with logistic regression models and multivariate Cox regression models. In addition, an analysis of participants’ satisfaction with food services will be carried out. The study was approved by the Ethics and Research Committee on 30/09/2020, approved for funding on 02/12/2021 and with registration number RBR-5jnbyhk in the Brazilian clinical trials database (ReBEC) for observational studies. Discussion Some studies address nutritional status or dysphagia in older people in various care settings. However, there is a lack of large sample studies including both processes of the impact of hospitalization. The results of the project will provide information on the incidence and prevalence of both pathologies in the study subjects, their associated factors and their relationship with the average length of stay, mortality and early readmission. In addition, early detection of a problem such as malnutrition related to the disease and/or dysphagia during a hospital stay will favor the action of professionals to resolve both pathologies and improve the health status of patients.This study has been funded by Instituto de Salud Carlos III (ISCIII) through the Project "PI21/00738" and co-funded by the European Union. The funders did not and will not have a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

    Impact of hospitalization on nutritional status in persons aged 65 years and over (NUTRIFRAG Study): Protocol for a prospective observational study

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    Background: Malnutrition is a recurring problem that has become more relevant in recent years. The aim of this study is to assess the risk of malnutrition and nutritional status on admission and its evolution until discharge in patients aged 65 and over admitted to medical and surgical hospitalization units in hospitals of the Spanish National Health System. Methods: Prospective observational study to be carried out in the medical-surgical hospitalization units of 9 public hospitals between 01/09/2022 and 31/12/2024. Using consecutive sampling, a total of 4077 patients will be included (453 in each hospital). Variables included are related to the care process, functionality, cognition and comorbidity, risk profile, nutritional status and dysphagia; as well as frailty, dietary quality and contextual variables. The incidence of risk of malnutrition, undernutrition and dysphagia during the care process and at discharge will be calculated. The association with risk factors will be studied with logistic regression models and multivariate Cox regression models. In addition, an analysis of participants' satisfaction with food services will be carried out. The study was approved by the Ethics and Research Committee on 30/09/2020, approved for funding on 02/12/2021 and with registration number RBR-5jnbyhk in the Brazilian clinical trials database (ReBEC) for observational studies. Discussion: Some studies address nutritional status or dysphagia in older people in various care settings. However, there is a lack of large sample studies including both processes of the impact of hospitalization. The results of the project will provide information on the incidence and prevalence of both pathologies in the study subjects, their associated factors and their relationship with the average length of stay, mortality and early readmission. In addition, early detection of a problem such as malnutrition related to the disease and/or dysphagia during a hospital stay will favor the action of professionals to resolve both pathologies and improve the health status of patients.This study has been funded by Instituto de Salud Carlos III (ISCIII) through the project "PI21/00738" and co-funded by the European Union. The funders did not and will not have a role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.S

    La Ley orgánica 1/1982, de 5 de mayo, de protección civil del derecho al honor, a la intimidad personal y familiar y a la propia imagen

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    Este libro es un estudio completo y riguroso de la Ley española de protección del derecho al honor, a la intimidad personal e imagen, en la que se contienen, tanto reflexiones teóricas, como, sobre todo, una sistematización crítica de los conceptos jurisprudenciales en torno a la aplicación de la misma, los cuales son extrapolables a otros derechos, como el colombiano. Se abordan temas como el concepto de derecho al honor, la determinación de su titular (si puede serlo la persona jurídica) y los conflictos entre dicho derecho fundamental de la personalidad y las libertades de información y expresión, prestándose especial atención al deber de veracidad y a la doctrina del reportaje neutral

    COVID-19 Severity and Survival over Time in Patients with Hematologic Malignancies: A Population-Based Registry Study

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    Mortality rates for COVID-19 have declined over time in the general population, but data in patients with hematologic malignancies are contradictory. We identified independent prognostic factors for COVID-19 severity and survival in unvaccinated patients with hematologic malignancies, compared mortality rates over time and versus non-cancer inpatients, and investigated post COVID-19 condition. Data were analyzed from 1166 consecutive, eligible patients with hematologic malignancies from the population-based HEMATO-MADRID registry, Spain, with COVID-19 prior to vaccination roll-out, stratified into early (February–June 2020; n = 769 (66%)) and later (July 2020–February 2021; n = 397 (34%)) cohorts. Propensity-score matched non-cancer patients were identified from the SEMI-COVID registry. A lower proportion of patients were hospitalized in the later waves (54.2%) compared to the earlier (88.6%), OR 0.15, 95%CI 0.11–0.20. The proportion of hospitalized patients admitted to the ICU was higher in the later cohort (103/215, 47.9%) compared with the early cohort (170/681, 25.0%, 2.77; 2.01–3.82). The reduced 30-day mortality between early and later cohorts of non-cancer inpatients (29.6% vs. 12.6%, OR 0.34; 0.22–0.53) was not paralleled in inpatients with hematologic malignancies (32.3% vs. 34.8%, OR 1.12; 0.81–1.5). Among evaluable patients, 27.3% had post COVID-19 condition. These findings will help inform evidence-based preventive and therapeutic strategies for patients with hematologic malignancies and COVID-19 diagnosis.Depto. de MedicinaFac. de MedicinaTRUEFundación Madrileña de Hematología y HemoterapiaFundación Leucemia y LinfomaAsociación Madrileña de Hematología y Hemoterapiapu

    Manuales y textos de enseñanza en la universidad liberal : VII congreso internacional sobre la historia de las universidades hispánicas

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    Congreso Internacional de Historia de las Universidades Hispánicas (VII, 2004: Universidad Carlos III de Madrid)El libro edita las actas del VII Congreso internacional sobre la historia de las universidades hispánicas celebrado los días 16-18 de noviembre de 2000 en el campus de Colmenarejo de la Universidad Carlos III de Madrid. Fue una reunión científica monográfica sobre los manuales y textos de enseñanza en la universidad liberal. Contó con un conjunto de ponencias que se adentraron en los ámbitos de la economía, el derecho público, el derecho privado, la filosofía y la medicina. Otras muchas cuestiones fueron analizadas en las comunicaciones.Presentación / Manuel Ángel Bermejo Castrillo. -- Una ciencia peligrosa: la enseñanza de la economía en la Universidad española / Pedro Fraile Balbín. -- La enseñanza del derecho público en España. Un ensayo critico / Alfredo Gallego Anabitarte. -- La enseñanza del derecho privado en la Universidad liberal /Ángel M. López y López y Cecilia Gómez-Salvago Sánchez. -- La enseñanza de la filosofía en la Universidad decimonónica (Asignaturas y textos oficiales) / Antonio Jiménez García. -- Manuales y textos de enseñanza médica en la Universidad liberal: la España del siglo XIX / José M. López Piñero. -- ¿Política o Academia? La disputa en torno al texto de lógica en la escuela nacional preparatoria / María de Lourdes Alvarado. -- La enseñanza del derecho natural y de gentes: el libro de Heineccio / Antonio Álvarez de Morales. -- Manuales y libros de texto utilizados en las escuelas industriales españolas durante la época isabelina / José Manuel Cano Pavón. -- Las bibliotecas universitarias en España durante la revolución liberal / Genaro Luis García López. -- Il magistero di Corrado Segre a Torino. I quaderni manoscritti delle lezioni universitarie (1888-1924) / Livia Giacardi. -- Los manuales de literatura en la facultad de Filosofía (1846-1867) / Jean-Louis Guereña. -- Los asertos de conclusiones públicas de Filosofía en el Colegio del Rosario durante la época de la Universidad Central (1826-1842) / María Clara Guillén de Iriarte. -- Vattel larva detracta. Reflexiones sobre la recepción del Ius Publicum Europaeum en la Universidad preliberal española / Pablo Gutiérrez Vega. -- La enseñanza del derecho en la Argentina por dos pequeños grandes libros: el Álvarez y el prontuario de Castro / Alberto David Leiva. -- Los libros útiles o la utilidad de los libros. Manuales de derecho entre 1841 y 1845 / Manuel Martínez Neira. -- L’insegnamento della storia nell’università italiana dopo l’unità / Mauro Moretti e Ilaria Porciani. -- Manuales de historia de filosofía en España (s. XIX) / Laureano Robles. -- L’insegnamento della matematica all’università di Torino (1848-1948). Aspetti storici, istituzionali e scientifici / Clara Silvia Roero. -- La enseñanza del derecho natural en el último tercio del siglo XIX / Salvador Rus Rufino. -- Un español republicano en Argentina: Juan Bialet Massé. Sus textos de anatomía y manual de medicina legal / María Cristina Vera de Flachs. -- La docenza del giansenista Pietro Tamburini a Pavia nel periodo francese. Un esperimento di sintesi tra etica teologica e diritti dell’uomo all’ombra dell’albero della libertà /Emauela Verzella Pettiti. -- El sentido humanista de la Universidad. Comentario a un texto de 1930: Misión de la Universidad, de José Ortega y Gasset / Javier Zamora Bonill

    Population Genetic Structure of the Grasshopper Eyprepocnemis plorans in the South and East of the Iberian Peninsula

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    The grasshopper Eyprepocnemis plorans subsp. plorans harbors a very widespread polymorphism for supernumerary (B) chromosomes which appear to have arisen recently. These chromosomes behave as genomic parasites because they are harmful for the individuals carrying them and show meiotic drive in the initial stages of population invasion. The rapid increase in B chromosome frequency at intrapopulation level is thus granted by meiotic drive, but its spread among populations most likely depends on interpopulation gene flow. We analyze here the population genetic structure in 10 natural populations from two regions (in the south and east) of the Iberian Peninsula. The southern populations were coastal whereas the eastern ones were inland populations located at 260–655 m altitude. The analysis of 97 ISSR markers revealed significant genetic differentiation among populations (average GST = 0.129), and the Structure software and AMOVA indicated a significant genetic differentiation between southern and eastern populations. There was also significant isolation by distance (IBD) between populations. Remarkably, these results were roughly similar to those found when only the markers showing low or no dropout were included, suggesting that allelic dropout had negligible effects on population genetic analysis. We conclude that high gene flow helped this parasitic B chromosome to spread through most of the geographical range of the subspecies E. plorans plorans.This study was supported by a grant from the Spanish Ministerio de Ciencia e Innovación (CGL2009-11917), and was partially performed by FEDER funds. MIMP was supported by a fellowship (FPU) from the Spanish Ministerio de Ciencia e Innovación
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