1,169 research outputs found
Inter-areal coordination of columnar architectures during visual cortical development
The occurrence of a critical period of plasticity in the visual cortex has
long been established, yet its function in normal development is not fully
understood. Here we show that as the late phase of the critical period unfolds,
different areas of cat visual cortex develop in a coordinated manner.
Orientation columns in areas V1 and V2 become matched in size in regions that
are mutually connected. The same age trend is found for such regions in the
left and right brain hemisphere. Our results indicate that a function of
critical period plasticity is to progressively coordinate the functional
architectures of different cortical areas - even across hemispheres.Comment: 30 pages, 1 table, 6 figure
Evidence of very low metallicity and high ionization state in a strongly lensed, star-forming dwarf galaxy at z=3.417
We investigate the gas-phase metallicity and Lyman Continuum (LyC) escape
fraction of a strongly gravitationally lensed, extreme emission-line galaxy at
z=3.417, J1000+0221S, recently discovered by the CANDELS team. We derive
ionization and metallicity sensitive emission-line ratios from H+K band
LBT/LUCI medium resolution spectroscopy. J1000+0221S shows high ionization
conditions, as evidenced by its enhanced [OIII]/[OII] and [OIII]/Hbeta ratios.
Consistently, strong-line methods based on the available line ratios suggest
that J1000+0221S is an extremely metal-poor galaxy, with a metallicity of
12+log(O/H) < 7.44 (< 5% solar), placing it among the most metal-poor
star-forming galaxies at z > 3 discovered so far. In combination with its low
stellar mass (2x10^8 Msun) and high star formation rate (5 Msun/yr), the
metallicity of J1000+0221S is consistent with the extrapolation to low masses
of the mass-metallicity relation traced by Lyman-break galaxies at z > 3, but
it is 0.55 dex lower than predicted by the fundamental metallicity relation at
z < 2.5. These observations suggest the picture of a rapidly growing galaxy,
possibly fed by the massive accretion of pristine gas. Additionally, deep
LBT/LBC in the UGR bands are used to derive a limit to the LyC escape fraction,
thus allowing us to explore for the first time the regime of sub-L* galaxies at
z > 3. We find a 1sigma upper limit to the escape fraction of 23%, which adds a
new observational constraint to recent theoretical models predicting that
sub-L* galaxies at high-z have high escape fractions and thus are the
responsible for the reioization of the Universe.Comment: 5 pages, 3 figures and 1 table. Accepted for publication in ApJ
Letter
Clues to the formation of spiral structure in M51 from the ages and locations of star clusters
We determine the spatial distributions of star clusters at different ages in the grand-design spiral galaxy M51 using a new catalog based on multi-band images taken with the Hubble Space Telescope (HST). These distributions, when compared with the spiral structure defined by molecular gas, dust, young and old stars, show the following sequence in the inner arms: dense molecular gas (and dust) defines the inner edge of the spiral structure, followed by an overdensity of old stars and then young stellar clusters. The offset between gas and young clusters in the inner arms is consistent with the expectations for a density wave. Clusters as old as a few hundred Myr remain concentrated close to the spiral arms, although the distributions are broader than those for the youngest clusters, which is also consistent with predictions from density wave simulations. The outermost portion of the west arm is different from the rest of the spiral structure in that it contains primarily intermediate-age (approximate to 100-400 Myr) clusters; we believe that this is a "material" arm. We have identified four "feathers," stellar structures beyond the inner arms that have a larger pitch angle than the arms. We do not find age gradients along any of the feathers, but the least coherent feathers appear to have the largest range of cluster ages
The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy
Structural analysis of protein fibrillation is inherently challenging. Given the crucial role of fibrils in amyloid diseases, method advancement is urgently needed. A hybrid modelling approach is presented enabling detailed analysis of a highly ordered and hierarchically organized fibril of the GNNQQNY peptide fragment of a yeast prion protein. Data from small-angle X-ray solution scattering, fibre diffraction and electron microscopy are combined with existing high-resolution X-ray crystallographic structures to investigate the fibrillation process and the hierarchical fibril structure of the peptide fragment. The elongation of these fibrils proceeds without the accumulation of any detectable amount of intermediate oligomeric species, as is otherwise reported for, for example, glucagon, insulin and [alpha]-synuclein. Ribbons constituted of linearly arranged protofilaments are formed. An additional hierarchical layer is generated via the pairing of ribbons during fibril maturation. Based on the complementary data, a quasi-atomic resolution model of the protofilament peptide arrangement is suggested. The peptide structure appears in a [beta]-sheet arrangement reminiscent of the [beta]-zipper structures evident from high-resolution crystal structures, with specific differences in the relative peptide orientation. The complexity of protein fibrillation and structure emphasizes the need to use multiple complementary methods
Imaging of electric and magnetic fields near plasmonic nanowires
Near-field imaging is a powerful tool to investigate the complex structure of light at the nanoscale. Recent advances in near-field imaging have indicated the possibility for the complete reconstruction of both electric and magnetic components of the evanescent field. Here we study the electro-magnetic field structure of surface plasmon polariton waves propagating along subwavelength gold nanowires by performing phase- and polarization-resolved near-field microscopy in collection mode. By applying the optical reciprocity theorem, we describe the signal collected by the probe as an overlap integral of the nanowire’s evanescent field and the probe’s response function. As a result, we find that the probe’s sensitivity to the magnetic field is approximately equal to its sensitivity to the electric field. Through rigorous modeling of the nanowire mode as well as the aperture probe response function, we obtain a good agreement between experimentally measured signals and a numerical model. Our findings provide a better understanding of aperture-based near-field imaging of the nanoscopic plasmonic and photonic structures and are helpful for the interpretation of future near-field experiments
Not In Our Backyard: Spectroscopic Support for the CLASH z=11 Candidate MACS0647-JD
We report on our first set of spectroscopic Hubble Space Telescope
observations of the z~11 candidate galaxy strongly lensed by the
MACSJ0647.7+7015 galaxy cluster. The three lensed images are faint and we show
that these early slitless grism observations are of sufficient depth to
investigate whether this high-redshift candidate, identified by its strong
photometric break at ~1.5 micron, could possibly be an emission line galaxy at
a much lower redshift. While such an interloper would imply the existence of a
rather peculiar object, we show here that such strong emission lines would
clearly have been detected. Comparing realistic, two-dimensional simulations to
these new observations we would expect the necessary emission lines to be
detected at >5 sigma while we see no evidence for such lines in the dispersed
data of any of the three lensed images. We therefore exclude that this object
could be a low redshift emission line interloper, which significantly increases
the likelihood of this candidate being a bona fide z~11 galaxy.Comment: 14 Pages. 6 Figures. 2nd revised version. Accepted. To appear in ApJ.
Please contact [email protected] for comments on this pape
Imaging of electric and magnetic fields near plasmonic nanowires.
Near-field imaging is a powerful tool to investigate the complex structure of light at the nanoscale. Recent advances in near-field imaging have indicated the possibility for the complete reconstruction of both electric and magnetic components of the evanescent field. Here we study the electro-magnetic field structure of surface plasmon polariton waves propagating along subwavelength gold nanowires by performing phase- and polarization-resolved near-field microscopy in collection mode. By applying the optical reciprocity theorem, we describe the signal collected by the probe as an overlap integral of the nanowire's evanescent field and the probe's response function. As a result, we find that the probe's sensitivity to the magnetic field is approximately equal to its sensitivity to the electric field. Through rigorous modeling of the nanowire mode as well as the aperture probe response function, we obtain a good agreement between experimentally measured signals and a numerical model. Our findings provide a better understanding of aperture-based near-field imaging of the nanoscopic plasmonic and photonic structures and are helpful for the interpretation of future near-field experiments
Discovery of a Ringlike Dark Matter Structure in the Core of the Galaxy Cluster Cl 0024+17
We present a comprehensive mass reconstruction of the rich galaxy cluster Cl
0024+17 at z~0.4 from ACS data, unifying both strong- and weak-lensing
constraints. The weak-lensing signal from a dense distribution of background
galaxies (~120 per square arcmin) across the cluster enables the derivation of
a high-resolution parameter-free mass map. The strongly-lensed objects tightly
constrain the mass structure of the cluster inner region on an absolute scale,
breaking the mass-sheet degeneracy. The mass reconstruction of Cl 0024+17
obtained in such a way is remarkable. It reveals a ringlike dark matter
substructure at r~75" surrounding a soft, dense core at r~50". We interpret
this peculiar sub-structure as the result of a high-speed line-of-sight
collision of two massive clusters 1-2 Gyr ago. Such an event is also indicated
by the cluster velocity distribution. Our numerical simulation with purely
collisionless particles demonstrates that such density ripples can arise by
radially expanding, decelerating particles that originally comprised the
pre-collision cores. Cl 0024+17 can be likened to the bullet cluster 1E0657-56,
but viewed the collision axis at a much later epoch. In addition, we
show that the long-standing mass discrepancy for Cl 0024+17 between X-ray and
lensing can be resolved by treating the cluster X-ray emission as coming from a
superposition of two X-ray systems. The cluster's unusual X-ray surface
brightness profile that requires a two isothermal sphere description supports
this hypothesis.Comment: To appear in the June 1 issue of The Astrophysical Journa
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