Life history of the Critically Endangered largetooth sawfish: a compilation of data for population assessment and demographic modelling

© The authors 2021. Open Access under Creative Commons by Attribution Licence. Use, distribution and reproduction are un - restricted. Authors and original publication must be credited. The largetooth sawfish Pristis pristis is a Critically Endangered, once widespread shark-like ray. The species is now extinct or severely depleted in many former parts of its range and is protected in some other range states where populations persist. The likelihood of collecting substantial new biological information is now low. Here, we review all available life history information on size, age and growth, reproductive biology, and demography as a resource for population assessment and demographic modelling. We also revisit a subset of historical data from the 1970s to examine the maternal size−litter size relationship. All available information on life history is derived from the Indo-West Pacific (i.e. northern Australia) and the Western Atlantic (i.e. Lake Nicaragua-Río San Juan system in Central America) subpopulations. P. pristis reaches a maximum size of at least 705 cm total length (TL), size-at-birth is 72−90 cm TL, female size-at-maturity is reached by 300 cm TL, male size-at-maturity is 280−300 cm TL, age-at-maturity is 8−10 yr, longevity is 30−36 yr, litter size range is 1−20 (mean of 7.3 in Lake Nicaragua), and reproductive periodicity is suspected to be biennial in Lake Nicaragua (Western Atlantic) but annual in Australia (Indo-West Pacific). There was a weak relationship between litter size and maternal size in Lake Nicaragua, and lifetime reproductive output for an individual female from Lake Nicaragua was estimated as 73 pups. Future demographic models should aim to capture the variability and uncertainty in life history parameters for P. pristis and we encourage a conservative approach to any application for conservation and management

CHIMERA: a wide-field, multi-colour, high-speed photometer at the prime focus of the Hale telescope

The Caltech HIgh-speed Multi-colour camERA (CHIMERA) is a new instrument that has been developed for use at the prime focus of the Hale 200-inch telescope. Simultaneous optical imaging in two bands is enabled by a dichroic beam splitter centred at 567 nm, with Sloan u′ and g′ bands available on the blue arm and Sloan r′, i′ and z_s bands available on the red arm. Additional narrow-band filters will also become available as required. An electron multiplying CCD (EMCCD) detector is employed for both optical channels, each capable of simultaneously delivering sub-electron effective read noise under multiplication gain and frame rates of up to 26 fps full frame (several 1000 fps windowed), over a fully corrected 5 × 5 arcmin field of view. CHIMERA was primarily developed to enable the characterization of the size distribution of sub-km Kuiper Belt Objects via stellar occultation, a science case that motivates the frame-rate, the simultaneous multi-colour imaging and the wide field of view of the instrument. In addition, it also has unique capability in the detection of faint near-Earth asteroids and will be used for the monitoring of short-duration transient and periodic sources, particularly those discovered by the intermediate Palomar Transient Factory (iPTF), and the upcoming Zwicky Transient Facility (ZTF)

A recent change in the optical and γ-ray polarization of the Crab nebula and pulsar

We report on observations of the polarization of optical and γ-ray photons from the Crab nebula and pulsar system using the Galway Astronomical Stokes Polarimeter (GASP), the Hubble Space Telescope, Advanced Camera for Surveys and the International Gamma-Ray Astrophysics Laboratory satellite (INTEGRAL). These, when combined with other optical polarization observations, suggest that the polarized optical emission and γ-ray polarization changes in a similar manner. A change in the optical polarization angle has been observed by this work, from 109.5 ± 0∘.7 in 2005 to 85.3 ± 1∘.4 in 2012. On the other hand, the γ-ray polarization angle changed from 115 ± 11° in 2003–2007 to 80 ± 12° in 2012–2014. Strong flaring activities have been detected in the Crab nebula over the past few years by the high-energy γ-ray missions Agile and Fermi, and magnetic reconnection processes have been suggested to explain these observations. The change in the polarized optical and γ-ray emission of the Crab nebula/pulsar as observed, for the first time, by GASP and INTEGRAL may indicate that reconnection is possibly at work in the Crab nebula. We also report, for the first time, a non-zero measure of the optical circular polarization from the Crab pulsar+knot system

Dispute settlement understanding on the use of BOTOX® in chronic migraine

[No abstract available

Can ecosystem-based deep-sea fishing be sustained?

Can there ever be a truly sustainable deep-sea fishery and if so, where and under what conditions? Ecosystembased fisheries management requires that this question be addressed such that habitat, bycatch species, and targeted fish populations are considered together within an ecosystem context. To this end, we convened the first workshop to develop an ecosystem approach to deep-sea fisheries and to ask whether deep-sea species could be fished sustainably. The workshop participants were able to integrate bycatch information into their framework but found it more difficult to integrate other ecosystem indicators such as habitat characteristics. (First two paragraphs from the Executive Summary

Aerial dissemination of Clostridium difficile spores

Background: Clostridium difficile-associated diarrhoea (CDAD) is a frequently occurring healthcare-associated infection, which is responsible for significant morbidity and mortality amongst elderly patients in healthcare facilities. Environmental contamination is known to play an important contributory role in the spread of CDAD and it is suspected that contamination might be occurring as a result of aerial dissemination of C. difficile spores. However previous studies have failed to isolate C. difficile from air in hospitals. In an attempt to clarify this issue we undertook a short controlled pilot study in an elderly care ward with the aim of culturing C. difficile from the air. Methods: In a survey undertaken during February (two days) 2006 and March (two days) 2007, air samples were collected using a portable cyclone sampler and surface samples collected using contact plates in a UK hospital. Sampling took place in a six bedded elderly care bay (Study) during February 2006 and in March 2007 both the study bay and a four bedded orthopaedic bay (Control). Particulate material from the air was collected in Ringer's solution, alcohol shocked and plated out in triplicate onto Brazier's CCEY agar without egg yolk, but supplemented with 5 mg/L of lysozyme. After incubation, the identity of isolates was confirmed by standard techniques. Ribotyping and REP-PCR fingerprinting were used to further characterise isolates. Results: On both days in February 2006, C. difficile was cultured from the air with 23 samples yielding the bacterium (mean counts 53 – 426 cfu/m3 of air). One representative isolate from each of these was characterized further. Of the 23 isolates, 22 were ribotype 001 and were indistinguishable on REP-PCR typing. C. difficile was not cultured from the air or surfaces of either hospital bay during the two days in March 2007. Conclusion: This pilot study produced clear evidence of sporadic aerial dissemination of spores of a clone of C. difficile, a finding which may help to explain why CDAD is so persistent within hospitals and difficult to eradicate. Although preliminary, the findings reinforce concerns that current C. difficile control measures may be inadequate and suggest that improved ward ventilation may help to reduce the spread of CDAD in healthcare facilities

Bycatch weight, composition and preliminary estimates of the impact of bycatch reduction devices in Queensland's trawl fishery

This report provides quantitative information on the effects of turtle excluder devices (TEDs) and bycatch reduction devices (BRDs) on the catch rates of bycatch, prawns, scallops and byproduct species, such as Moreton Bay bugs and Balmain bugs, in Queensland’s major trawl fishing sectors. It also provides biological information on, and management advice for several species referred to in the Fishery Management Plan as the permitted species. Several recommendations are included for reducing bycatch in the trawl fishery and for sustaining stocks of the permitted species

Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course and outcome

<p>Abstract</p> <p>Background</p> <p><it>Clostridium difficile</it>-associated disease (CDAD) is a serious nosocomial infection, however few studies have assessed CDAD outcome in the intensive care unit (ICU). We evaluated the epidemiology, clinical course and outcome of hospital-acquired CDAD in the critical care setting.</p> <p>Methods</p> <p>We performed a historical cohort study on 58 adults with a positive <it>C. difficile </it>cytotoxin assay result occurring in intensive care units.</p> <p>Results</p> <p>Sixty-two percent of patients had concurrent infections, 50% of which were bloodstream infections. The most frequently prescribed antimicrobials prior to CDAD were anti-anaerobic agents (60.3%). Septic shock occurred in 32.8% of CDAD patients. The in-hospital mortality was 27.6%. Univariate analysis revealed that SOFA score, at least one organ failure and age were predictors of mortality. Charlson score ≥3, gender, concurrent infection, and number of days with diarrhea before a positive <it>C. difficile </it>toxin assay were not significant predictors of mortality on univariate analysis. Independent predictors for death were SOFA score at infection onset (per 1-point increment, OR 1.40; CI95 1.13–1.75) and age (per 1-year increment, OR 1.10; CI95 1.02–1.19).</p> <p>Conclusion</p> <p>In ICU patients with CDAD, advanced age and increased severity of illness at the onset of infection, as measured by the SOFA score, are independent predictors of death.</p

Clostridium difficile infection among hospitalized HIV-infected individuals: epidemiology and risk factors: results from a case-control study (2002-2013).

BACKGROUND: HIV infection is a risk factor for Clostridium difficile infection (CDI) yet the immune deficiency predisposing to CDI is not well understood, despite an increasing incidence of CDI among such individuals. We aimed to estimate the incidence and to evaluate the risk factors of CDI among an HIV cohort in Italy. METHODS: We conducted a retrospective case-control (1:2) study. Clinical records of HIV inpatients admitted to the National Institute for Infectious Disease "L. Spallanzani", Rome, were reviewed (2002-2013). CASES: HIV inpatients with HO-HCFA CDI, and controls: HIV inpatients without CDI, were matched by gender and age. Logistic regression was used to identify risk factors associated with CDI. RESULTS: We found 79 CDI episodes (5.1 per 1000 HIV hospital admissions, 3.4 per 10000 HIV patient-days). The mean age of cases was 46 years. At univariate analysis factors associated with CDI included: antimycobacterial drug exposure, treatment for Pneumocystis pneumonia, acid suppressant exposure, previous hospitalization, antibiotic exposure, low CD4 cell count, high Charlson score, low creatinine, low albumin and low gammaglobulin level. Using multivariate analysis, lower gammaglobulin level and low serum albumin at admission were independently associated with CDI among HIV-infected patients. CONCLUSIONS: Low gammaglobulin and low albumin levels at admission are associated with an increased risk of developing CDI. A deficiency in humoral immunity appears to play a major role in the development of CDI. The potential protective role of albumin warrants further investigation

Extinction risk and conservation of the world\u27s sharks and rays

The rapid expansion of human activities threatens ocean-wide biodiversity. Numerous marine animal populations have declined, yet it remains unclear whether these trends are symptomatic of a chronic accumulation of global marine extinction risk. We present the first systematic analysis of threat for a globally distributed lineage of 1,041 chondrichthyan fishes&mdash;sharks, rays, and chimaeras. We estimate that one-quarter are threatened according to IUCN Red List criteria due to overfishing (targeted and incidental). Large-bodied, shallow-water species are at greatest risk and five out of the seven most threatened families are rays. Overall chondrichthyan extinction risk is substantially higher than for most other vertebrates, and only one-third of species are considered safe. Population depletion has occurred throughout the world&rsquo;s ice-free waters, but is particularly prevalent in the Indo-Pacific Biodiversity Triangle and Mediterranean Sea. Improved management of fisheries and trade is urgently needed to avoid extinctions and promote population recovery