Student Centered Landscape Scenarios In Winter City University Campuses: Erzurum Atatürk University Case

World population which is increasing day by day andurbanization as a result of it has caused deterioration in naturalenvironment. Maintainability concept has been an importantcriterion in new planning and design studies for decreasing theseproblems. In this sense universities contributing tomaintainability targets positively, contributes to physicaldevelopment of city and environmental plans by providing greenareas open to the whole city. However, recreational activitiesbeing done in campuses increase self-reliance and respectabilityof young individuals by creating nature exploring, social sharingand personal awareness especially for students.In this student centered study being done in Atatürk University itwas aimed to give some suggestions for alternative outdoorplayfields which will satisfy social, cultural and recreationalneeds of students for four seasons. Moreover, indoor and outdoorwinter recreational areas for all year long and some possibleplaces in which students will have fun were given as suggestions.Approximate 150 questionnaire studies were done randomly infaculties, which are in campus and have student density anddemands of students for recreational usage and outdoor sports inthe direction of utilization of campus and their needs weredetermined. Moreover, indoor and outdoor winter recreationalareas in the campus which will satisfy needs of students for allyear long and some possible places in which students will havefun were given as suggestions

Space syntax-based analysis method to improve the accessibility of urban tourism in a historic environment Tarihi bir çevrede kent turizminin erişilebilirliğini geliştirmek için mekan dizimine (space syntax) dayalı bir analiz yöntemi

Urban centers have traditionally been points of attraction for local and international visitors. The most important point that will enable urban spaces to form meaningful integrity is the relational structures of spaces. The renewal of cities over time and the use of historical heritage sites by people for tourism purposes will contribute to the understanding of the urban identity by improving the structural and social structure of the city. In the study, Space syntax analysis method was used, which enables the comparative analysis of the relations between the structural features of the historical spaces in Erzurum city center in terms of functionality and the shaping features of the spaces, and tells the story of how the performance of the spaces is affected by the physical and spatial form. The city center was drawn and digitized. Integration value was calculated by performing Axial and Segment analysis of the drawn map in the depthmap X-0.8.0 program. Based on the integration link in accessibility, tourist route and people flow with the maps and statistical charts of Space Syntax, it is aimed to evaluate the street network and functionality performance. The effects of the combination between the route of the city's historical sites and critical points based on the street-avenue network and the functionality, transportation and integration attractiveness of existing historical sites have been determined. In the parts of the city where the historical texture is dense, the relation network between the built environment and the city, access-transportation and social relations are interpreted. As a result, it has been determined that while foreign tourists prefer to wander on the streets with high global integration, local people prefer streets with high local integration. It has been revealed that axes with high global integration constitute a much more important route for tourists

Burden of paediatric pyoderma and scabies in North West Queensland

Aim The study aims to assess the health burden of children admitted with 'scabies' to Mt Isa Hospital, the referral centre for North West Queensland, from 2006 to 2010. Methods This is a retrospective chart audit of admissions of children with 'scabies' including age, sex, date, residence, Indigenous status, result of skin swabs and length of stay, and the number of admissions with acute rheumatic fever (ARF) and acute post-streptococcal glomerulo-nephritis (APSGN) in that period. Financial burden was estimated from daily bed costs and transportation. Results There were 113 admissions with mean age of 23/12: 11% were <2/12 and mean stay was 4.5 days. 19 were admitted twice, 5 thrice and 2 four times. 7 individuals accounted for 25% of admissions. 'Scabies' accounted for 10.1% of medical admissions <5 years of age. Admissions increased from 10 in 2005 to 39 in 2010. The minimum cost per admission was 9584.07. Seventy-one per cent of swabs grew Group A streptococcus, all sensitive to penicillin. Sixty-three per cent of these were accompanied by Staphylococcus aureus, which was the sole organism in 18%. Sixty-four per cent of S. aureus were methicillin resistant. There were 29 admissions for ARF and 23 with APSGN. All children with 'scabies' and ARF and all but three with APSGN were Indigenous. Conclusion Pyoderma and scabies are major health burdens in North West Queensland, requiring organised community-based prevention. The number of repeat admissions emphasises the futility of individual treatment

Hallucinations in severe, repeated Sydenham's chorea in an indigenous girl in North-West Queensland

Sydenham's chorea is a cardinal feature of rheumatic fever. It is known by its dyskinesia and susceptibility to carditis, but associated psychiatric disorder is being recognised. This has included tics and obsessive compulsive disorder, but we report hallucinations in an indigenous girl, suffering her third bout of chorea

Does biomarker use in oncology improve clinical trial failure risk? A large-scale analysis

To date there has not been an extensive analysis of the outcomes of biomarker use in oncology. Data were pooled across four indications in oncology drawing upon trial outcomes from www.clinicaltrials.gov: breast cancer, non-small cell lung cancer (NSCLC), melanoma and colorectal cancer from 1998 to 2017. We compared the likelihood drugs would progress through the stages of clinical trial testing to approval based on biomarker status. This was done with multi-state Markov models, tools that describe the stochastic process in which subjects move among a finite number of states. Over 10000 trials were screened, which yielded 745 drugs. The inclusion of biomarker status as a covariate significantly improved the fit of the Markov model in describing the drug trajectories through clinical trial testing stages. Hazard ratios based on the Markov models revealed the likelihood of drug approval with biomarkers having nearly a fivefold increase for all indications combined. A 12, 8 and 7-fold hazard ratio was observed for breast cancer, melanoma and NSCLC, respectively. Markov models with exploratory biomarkers outperformed Markov models with no biomarkers. This is the first systematic statistical evidence that biomarkers clearly increase clinical trial success rates in three different indications in oncology. Also, exploratory biomarkers, long before they are properly validated, appear to improve success rates in oncology. This supports early and aggressive adoption of biomarkers in oncology clinical trials