6,635 research outputs found

    Morpho-functional basis of endothelial dysfunction in diabetes mellitus

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    The diabetes mellitus (DM) inevitably progresses and leads to complications, among which the main place is occupied by micro- and macroangiopathies. The presence of endothelial damage in DM can be established even before macroscopically significant damage to the vessel. At the same time, there is no summary ED characteristic for diabetes. The aim of the study is to make a comprehensive evaluation of ED in DM -1 and DM-2 types.Materials and methods of research. 60 persons, including 53 DM type 1 and type 2, with a severe course (state of decompensation) participated in the present study. We used the method of estimating ED by the number of circulating desquamation endothelial cells (CECs) at the stages of decomposition with simultaneous determination of NO2- and NO3- metabolites of nitric oxide.Results and discussion. In patients with diabetes, the level of CECs increased in 3-5 times and ranged from 1800 to 11,200 cells / ml. The average amount of CECs in patients with diabetes was 3358.5 ± 366.3 cells / ml.Conclusions: Endothelium is involved in the pathological process at DM. This is evidenced by a significant increase in CECs in the blood plasma. The use of this method allows to detect ED before clinically considerable vascular impairment and reflects the severity of the course and duration of DM

    An Exact Solution for the Lattice Gas Model in One Dimension

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    A simple method to obtain a canonical partition function for one dimensional lattice gas model is presented. The simplification is based upon rewriting a sum over all possible configurations to a sum over numbers of clusters in the system.Comment: 6 pages, LaTe

    Optical studies of the X-ray transient XTE J2123-058 -I. Photometry

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    We present optical photometry of the X-ray transient XTE J2123-058, obtained in July-October 1998. The light curves are strongly modulated on the 5.95hrs orbital period, and exhibit dramatic changes in amplitude and form during the decline. We used synthetic models which include the effect of partial eclipses and X-ray heating effects, to estimate the system parameters, and we constrain the binary inclination to be i=73+-4 degrees. The model is successful in reproducing the light curves at different stages of the decay by requiring the accretion disc to become smaller and thinner by 30% as the system fades by 1.7 mags in the optical. From Aug 26 the system reaches quiescence with a mean magnitude of R=21.7+-0.1 and our data are consistent with the optical variability being dominated by the companion's ellipsoidal modulation.Comment: 6 pages, 6 figure

    On Graph-Theoretic Identifications of Adinkras, Supersymmetry Representations and Superfields

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    In this paper we discuss off-shell representations of N-extended supersymmetry in one dimension, ie, N-extended supersymmetric quantum mechanics, and following earlier work on the subject codify them in terms of certain graphs, called Adinkras. This framework provides a method of generating all Adinkras with the same topology, and so also all the corresponding irreducible supersymmetric multiplets. We develop some graph theoretic techniques to understand these diagrams in terms of a relatively small amount of information, namely, at what heights various vertices of the graph should be "hung". We then show how Adinkras that are the graphs of N-dimensional cubes can be obtained as the Adinkra for superfields satisfying constraints that involve superderivatives. This dramatically widens the range of supermultiplets that can be described using the superspace formalism and organizes them. Other topologies for Adinkras are possible, and we show that it is reasonable that these are also the result of constraining superfields using superderivatives. The family of Adinkras with an N-cubical topology, and so also the sequence of corresponding irreducible supersymmetric multiplets, are arranged in a cyclical sequence called the main sequence. We produce the N=1 and N=2 main sequences in detail, and indicate some aspects of the situation for higher N.Comment: LaTeX, 58 pages, 52 illustrations in color; minor typos correcte

    On a class of 2D integrable lattice equations

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    We develop a new approach to the classification of integrable equations of the form uxy=f(u,ux,uy,zuzˉu,zzˉu), u_{xy}=f(u, u_x, u_y, \triangle_z u \triangle_{\bar z}u, \triangle_{z\bar z}u), where z\triangle_{ z} and zˉ\triangle_{\bar z} are the forward/backward discrete derivatives. The following 2-step classification procedure is proposed: (1) First we require that the dispersionless limit of the equation is integrable, that is, its characteristic variety defines a conformal structure which is Einstein-Weyl on every solution. (2) Secondly, to the candidate equations selected at the previous step we apply the test of Darboux integrability of reductions obtained by imposing suitable cut-off conditions

    The influence of multilayer metal-carbon coatings composition with different arrangement of functional layers on their surface morphology

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    This research was supported by the grants of Belarussian Republican Foundation for Fundamental Research BRFFR № T17KIG-009

    Cluster state generation using van der Waals and dipole-dipole interactions in optical lattices

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    We present a scalable method for generation of a cluster state for measurement-based quantum computing using van der Waals or dipole-dipole interactions between neutral atoms or polar molecules in an optical lattice. Nearest neighbor entanglement is accomplished by performing a phase gate using interaction of atoms in Rydberg states or molecules in large dipole moment states. All nearest neighbors are sequentially entangled in a finite number of operations, independent of the number of qubits, producing a 1D cluster state. A universal 2D cluster state can be generated in several ms in a two-dimensional optical lattice by producing a series of 1D cluster states in one lattice direction, followed by application of the entangling operations in another lattice direction. We discuss the viability of the scheme with Rb Rydberg atoms.Comment: Revised and expanded versio

    The influence of motor activity on the development of cardiac arrhythmias during experimental emotional stress

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    Experimental emotional stress which can produce various disorders of cardiac rhythm: sinus tachycardia, atrial fibrillation, ventricular, extrasystoles and paroxysmal ventricular tachysystoles was studied. In these conditions the adrenalin content in the blood and myocardium is increased 3 to 4 times. It is found that moderate motor activity leads to a relative decrease of adrenalin in the myocardium and arrest of cardiac arrhythmias
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