Real-World Evidence: How Long Do Our Patients Fast?—Results from a Prospective JAGO-NOGGO-Multicenter Analysis on Perioperative Fasting in 924 Patients with Malignant and Benign Gynecological Diseases

Simple Summary: The concept of ERAS (Enhanced Recovery After Surgery) was introduced to reduce perioperative morbidity through a multimodal approach. Optimized and shortened perioperative fasting is a fundamental part of this modern concept of perioperative patient management, as prolonged fasting before and after surgery is associated with unfavorable outcomes. So far, it remains unclear whether increasingly established ERAS protocols lead to adequate short fasting intervals in clinical routines. We therefore conducted this prospective multicenter study and collected real-world data from 924 patients to evaluate actual perioperative fasting behavior. Patients reported drastically prolonged perioperative fasting durations. Even longer fasting intervals were reported for oncological and extensive procedures. Our data suggest that modern optimized fasting management is poorly implemented in clinical routine practice. This study should draw attention to the need for adequate implementation of ERAS protocols and sensitize clinicians to appropriate patient education about perioperative fasting. Background: Despite the key role of optimized fasting in modern perioperative patient management, little current data exist on perioperative fasting intervals in routine clinical practice. Methods: In this multicenter prospective study, the length of pre- and postoperative fasting intervals was assessed with the use of a specifically developed questionnaire. Between 15 January 2021 and 31 May 2022, 924 gynecology patients were included, from 13 German gynecology departments. Results: On average, patients remained fasting for about three times as long as recommended for solid foods (17:02 +/- 06:54 h) and about five times as long as recommended for clear fluids (9:21 +/- 5:48 h). The average perioperative fasting interval exceeded one day (28:23 +/- 14:02 h). Longer fasting intervals were observed before and after oncological or extensive procedures, while shorter preoperative fasting intervals were reported in the participating university hospitals. Smoking, treatment in a non-university hospital, an increased Charlson Comorbidity Index and extensive surgery were significant predictors of longer preoperative fasting from solid foods. In general, prolonged preoperative fasting was tolerated well and quality of patient information was perceived as good. Conclusion: Perioperative fasting intervals were drastically prolonged in this cohort of 924 gynecology patients. Our data indicate the need for better patient education about perioperative fasting

A Multilab Replication of the Ego Depletion Effect

There is an active debate regarding whether the ego depletion effect is real. A recent preregistered experiment with the Stroop task as the depleting task and the antisaccade task as the outcome task found a medium-level effect size. In the current research, we conducted a preregistered multilab replication of that experiment. Data from 12 labs across the globe (N = 1,775) revealed a small and significant ego depletion effect, d = 0.10. After excluding participants who might have responded randomly during the outcome task, the effect size increased to d = 0.16. By adding an informative, unbiased data point to the literature, our findings contribute to clarifying the existence, size, and generality of ego depletion

The anthropogenic pollutants in urban ponds based on the example of Słupsk

In areas of urban infrastructure, ponds play an important role. They are places of rest and recreation, and they facilitate contact between city dwellers and the aquatic environment. They are also a place for living waterflow and ichthyofauna. Urban ponds are susceptible to anthropogenic influences, and their self-cleaning capacity is limited due to their small size. The city of Słupsk is located in northern Poland. Coal combustion in domestic boilers and transport cause dust emissions to be released into the atmosphere. The concentration of particulate matter and heavy metals in PM10 in Słupsk is much higher than in neighbouring village Gać. This affects metals deposition from the atmosphere. Two urban ponds in Słupsk were the object of the research. Sampling station No. 1 was located in the southern part of the Raj Pond situated deep into the forest area, a considerable distance from urban buildings. Sampling station No. 2 was located at the Juniorów Pond located near the city centre. Water samples were taken from a depth of 10 cm. To investigate the deposition from the atmosphere, atmospheric precipitation was collected in a collector located in the city of Słupsk. The concentrations of Li, Al, Cr, Mn, Fe, Ni, Se, As, V, Sr, Cd and Pb were analyzed in the obtained water samples. Measurements were made using an ICP-MS mass spectrometer. From the obtained results, it was observed that the concentrations of Li, Al, Cr, Mn, Fe, Se, Sr and Cd were higher at station No. 2 located near the city centre

The anthropogenic pollutants in urban ponds based on the example of Słupsk

In areas of urban infrastructure, ponds play an important role. They are places of rest and recreation, and they facilitate contact between city dwellers and the aquatic environment. They are also a place for living waterflow and ichthyofauna. Urban ponds are susceptible to anthropogenic influences, and their self-cleaning capacity is limited due to their small size. The city of Słupsk is located in northern Poland. Coal combustion in domestic boilers and transport cause dust emissions to be released into the atmosphere. The concentration of particulate matter and heavy metals in PM10 in Słupsk is much higher than in neighbouring village Gać. This affects metals deposition from the atmosphere. Two urban ponds in Słupsk were the object of the research. Sampling station No. 1 was located in the southern part of the Raj Pond situated deep into the forest area, a considerable distance from urban buildings. Sampling station No. 2 was located at the Juniorów Pond located near the city centre. Water samples were taken from a depth of 10 cm. To investigate the deposition from the atmosphere, atmospheric precipitation was collected in a collector located in the city of Słupsk. The concentrations of Li, Al, Cr, Mn, Fe, Ni, Se, As, V, Sr, Cd and Pb were analyzed in the obtained water samples. Measurements were made using an ICP-MS mass spectrometer. From the obtained results, it was observed that the concentrations of Li, Al, Cr, Mn, Fe, Se, Sr and Cd were higher at station No. 2 located near the city centre

Real-World Evidence: How Long Do Our Patients Fast?—Results from a Prospective JAGO-NOGGO-Multicenter Analysis on Perioperative Fasting in 924 Patients with Malignant and Benign Gynecological Diseases

Background: Despite the key role of optimized fasting in modern perioperative patient management, little current data exist on perioperative fasting intervals in routine clinical practice. Methods: In this multicenter prospective study, the length of pre- and postoperative fasting intervals was assessed with the use of a specifically developed questionnaire. Between 15 January 2021 and 31 May 2022, 924 gynecology patients were included, from 13 German gynecology departments. Results: On average, patients remained fasting for about three times as long as recommended for solid foods (17:02 ± 06:54 h) and about five times as long as recommended for clear fluids (9:21 ± 5:48 h). The average perioperative fasting interval exceeded one day (28:23 ± 14:02 h). Longer fasting intervals were observed before and after oncological or extensive procedures, while shorter preoperative fasting intervals were reported in the participating university hospitals. Smoking, treatment in a non-university hospital, an increased Charlson Comorbidity Index and extensive surgery were significant predictors of longer preoperative fasting from solid foods. In general, prolonged preoperative fasting was tolerated well and quality of patient information was perceived as good. Conclusion: Perioperative fasting intervals were drastically prolonged in this cohort of 924 gynecology patients. Our data indicate the need for better patient education about perioperative fasting

A Multilab Replication of the Ego Depletion Effect

status: publishe

A Multilab Replication of the Ego Depletion Effect

10.1177/1948550619887702SOCIAL PSYCHOLOGICAL AND PERSONALITY SCIENCE12114-2

Multi-Lab Replication Reveals A Small but Significant Ego Depletion Effect

There is an active debate regarding whether the ego depletion effect is real. A recent pre-registered experiment with the Stroop task as the depleting task and the antisaccade task as the outcome task found a medium level effect size. In the current research, we pre-registered a multi-lab collaborating project to replicate that experiment. Data from twelve labs across the globe (N = 1775) revealed a small but significant ego depletion effect, g = 0.12, CI95 = [0.02, 0.21]. The data also provided some evidence in support of a moderating effect of individual differences in lay theory about willpower, such that participants with an unlimited-resource theory evinced a weaker depletion effect. Finally, a series of auxiliary analyses provided important implications for future studies investigating the robustness of ego depletion, such that strictly controlled experimental settings and outcome tasks with medium difficulty might be better for observing a stronger depletion effect