Scientific Opportunities with an X-ray Free-Electron Laser Oscillator

An X-ray free-electron laser oscillator (XFELO) is a new type of hard X-ray source that would produce fully coherent pulses with meV bandwidth and stable intensity. The XFELO complements existing sources based on self-amplified spontaneous emission (SASE) from high-gain X-ray free-electron lasers (XFEL) that produce ultra-short pulses with broad-band chaotic spectra. This report is based on discussions of scientific opportunities enabled by an XFELO during a workshop held at SLAC on June 29 - July 1, 2016Comment: 21 pages, 12 figure

Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser

Citation: Ekeberg, T., Svenda, M., Abergel, C., Maia, F., Seltzer, V., Claverie, J. M., . . . Hajdu, J. (2015). Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser. Physical Review Letters, 114(9), 6. doi:10.1103/PhysRevLett.114.098102We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.Additional Authors: Andersson, I.;Loh, N. D.;Martin, A. V.;Chapman, H.;Bostedt, C.;Bozek, J. D.;Ferguson, K. R.;Krzywinski, J.;Epp, S. W.;Rolles, D.;Rudenko, A.;Hartmann, R.;Kimmel, N.;Hajdu, J

Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser

10.1103/PhysRevLett.114.098102Physical Review Letters114909810

The soft x-ray instrument for materials studies at the linac coherent light source x-ray free-electron laser

This content may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This material originally appeared in Review of Scientific Instruments 83, 043107 (2012) and may be found at https://doi.org/10.1063/1.3698294.The soft x-ray materials science instrument is the second operational beamline at the linac coherent light source x-ray free electron laser. The instrument operates with a photon energy range of 480–2000 eV and features a grating monochromator as well as bendable refocusing mirrors. A broad range of experimental stations may be installed to study diverse scientific topics such as: ultrafast chemistry, surface science, highly correlated electron systems, matter under extreme conditions, and laboratory astrophysics. Preliminary commissioning results are presented including the first soft x-ray single-shot energy spectrum from a free electron laser

Intergenerational impacts of maternal mortality: Qualitative findings from rural Malawi

Background: Maternal mortality, although largely preventable, remains unacceptably high in developing countries such as Malawi and creates a number of intergenerational impacts. Few studies have investigated the far-reaching impacts of maternal death beyond infant survival. This study demonstrates the short- and long-term impacts of maternal death on children, families, and the community in order to raise awareness of the true costs of maternal mortality and poor maternal health care in Neno, a rural and remote district in Malawi. Methods: Qualitative in-depth interviews were conducted to assess the impact of maternal mortality on child, family, and community well-being. We conducted 20 key informant interviews, 20 stakeholder interviews, and six sex-stratified focus group discussions in the seven health centers that cover the district. Transcripts were translated, coded, and analyzed in NVivo 10. Results: Participants noted a number of far-reaching impacts on orphaned children, their new caretakers, and extended families following a maternal death. Female relatives typically took on caregiving responsibilities for orphaned children, regardless of the accompanying financial hardship and frequent lack of familial or governmental support. Maternal death exacerbated children’s vulnerabilities to long-term health and social impacts related to nutrition, education, employment, early partnership, pregnancy, and caretaking. Impacts were particularly salient for female children who were often forced to take on the majority of the household responsibilities. Participants cited a number of barriers to accessing quality child health care or support services, and many were unaware of programming available to assist them in raising orphaned children or how to access these services. Conclusions: In order to both reduce preventable maternal mortality and diminish the impacts on children, extended families, and communities, our findings highlight the importance of financing and implementing universal access to emergency obstetric and neonatal care, and contraception, as well as social protection programs, including among remote populations

Time-dependent dynamical Bragg diffraction in crystals by beam propagation method (BPM)

In this paper we describe how to solve time dependent x-ray dynamic diffraction problems in distorted crystal using a beam propagation method (BPM). We will show examples of using the BPM method to simulate propagation of x-ray beams in deformed crystals in space an time domain which are relevant to performance of x-ray optics at x-ray Free Electron Laser

Influence of imperfections in a wedged multilayer Laue lens for the focusing of X-rays investigated by beam propagation method

Using a beam propagation method the focusing properties of a one-dimensional wedged multilayer Laue lens with imperfections have been investigated theoretically. The calculations were done for a lens focusing 20 keV X-rays to <5 nm spot. Our simulations of the intensity in the focal plane and at the far screen show that the systematic errors degrade the performance more than the stochastic ones and that a proper image at the far screen is not a proof for a good quality beam in the focus

Soft x-ray self-seeding simulation methods and their application for the Linac Coherent Light Source

Self-seeding is a promising approach to significantly narrow the self-amplified spontaneous emission bandwidth of X-ray free-electron lasers (FELs) and hence to produce nearly transform-limited pulses. We study the radiation propagation through a grating monochromator installed at the Linac Coherent Light Source (LCLS). The monochromator design is based on a toroidal VLS grating working at a fixed incidence angle mounting without an entrance slit. It covers the spectral range from 500 eV to 1000 eV. The optical system was studied using a wave optics method to evaluate the performance of the self-seeding scheme. Our wave optics analysis takes into account the finite size of the coherent source, third-order aberrations and height error of the optical elements. Two propagation approaches are studied with time-dependent FEL simulations. In addition, the pulse-front tilt phenomenon effect is illustrated

Microbunch Rotation and Coherent Undulator Radiation from a Kicked Electron Beam

Coherent emission from a microbunched electron beam is the driving force behind the revolution in light sources, enabling x-ray free-electron lasers (FELs) to emit pulses 9 orders of magnitude brighter than previous sources. Microbunches form perpendicular to the electron travel direction, and the conventional understanding is that they shear rather than rotate in response to a transverse kick, locking FEL facilities into a single-user operating mode. In this paper, we show that microbunches rotate toward the new direction of travel if the electron beam is kicked and defocused. We provide evidence that microbunch rotation explains the unexpectedly large amount of off-axis radiation observed during experiments at the Linac Coherent Light Source. We demonstrate that LCLS can be multiplexed into at least three separate beams using this principle. Finally, we propose using a magnetic triplet to rotate microbunches through significantly larger angles without microbunch degradation. This new understanding of microbunch dynamics can lead to significantly improved multiplexing at FEL facilities, microbunch preservation through a bend, and x-ray pulses with a pulse-front tilt