2,399 research outputs found
On Hecke theory for Hermitian modular forms
In this paper we outline the Hecke theory for Hermitian modular forms in the
sense of Hel Braun for arbitrary class number of the attached
imaginary-quadratic number field. The Hecke algebra turns out to be
commutative. Its inert part has a structure analogous to the case of the Siegel
modular group and coincides with the tensor product of its -components for
inert primes . This leads to a characterization of the associated
Siegel-Eisenstein series. The proof also involves Hecke theory for particular
congruence subgroups
Thermodynamic properties of QCD in external magnetic fields
We consider the effect of strong external electromagnetic fields on
thermodynamic observables in QCD, through lattice simulations with 1+1+1
flavors of staggered quarks at physical quark masses. Continuum extrapolated
results are presented for the light quark condensates and for their tensor
polarizations, as functions of the temperature and the magnetic field. We find
the light condensates to undergo inverse magnetic catalysis in the transition
region, in a manner that the transition temperature decreases with growing
magnetic field. We also compare the results to other approaches and lattice
simulations. Furthermore, we relate the tensor polarization to the spin part of
the magnetic susceptibility of the QCD vacuum, and show that this contribution
is diamagnetic.Comment: 13 pages, 9 figures, talks presented by FB and GE at Xth Quark
Confinement and the Hadron Spectrum, 8-12 October 2012, TUM Campus Garching,
Munich, German
Averages of Fourier coefficients of Siegel modular forms and representation of binary quadratic forms by quadratic forms in four variables
Let be a a negative discriminant and let vary over a set of
representatives of the integral equivalence classes of integral binary
quadratic forms of discriminant . We prove an asymptotic formula for for the average over of the number of representations of by an
integral positive definite quaternary quadratic form and obtain results on
averages of Fourier coefficients of linear combinations of Siegel theta series.
We also find an asymptotic bound from below on the number of binary forms of
fixed discriminant which are represented by a given quaternary form. In
particular, we can show that for growing a positive proportion of the
binary quadratic forms of discriminant is represented by the given
quaternary quadratic form.Comment: v5: Some typos correcte
An effective chiral Hadron-Quark Equation of State
We construct an effective model for the QCD equation of state, taking into
account chiral symmetry restoration as well as the deconfinement phase
transition. The correct asymptotic degrees of freedom at the high and low
temperature limits are included (quarks hadrons). The model
shows a rapid crossover for both order parameters, as is expected from lattice
calculations. We then compare the thermodynamic properties of the model at
which turn out to be in qualitative agreement with lattice data,
while apparent quantitative differences can be attributed to hadronic
contributions and excluded volume corrections. Furthermore we discuss the
effects of a repulsive vector type quark interaction at finite baryon number
densities on the resulting phase diagram of the model. Our current model is
able to reproduce a first-order liquid gas phase transition as expected, but
does not show any signs of a first order deconfinement or chiral phase
transition. Both transitions rather appear as a very wide crossover in which
heavily medium modified hadron coexist with free quarks.Comment: 19 pages, 13 figures Version accepted by J. Phys.
Synovial sarcomas usually metastasize after >5 years: a multicenter retrospective analysis with minimum follow-up of 10 years for survivors
In SS, metastases develop late with high mortality. Patients with SS should be followed for >10 year
Intratracheal synthetic CpG oligodeoxynucleotide causes acute lung injury with systemic inflammatory response
Bacterial genome is characterized by frequent unmethylated cytosine-phosphate-guanine (CpG) motifs. Deleterious effects can occur when synthetic oligodeoxynucleotides (ODN) with unmethylated CpG dinucleotides (CpG-ODN) are administered in a systemic fashion. We aimed to evaluate the effect of intratracheal CpG-ODN on lung inflammation and systemic inflammatory response. C57BL/6J mice received intratracheal administration of CpG-ODN (0.01, 0.1, 1.0, 10, or 100 μM) or control ODN without CpG motif. Bronchoalveolar lavage (BAL) fluid was obtained 3 or 6 h or 1, 2, 7, or 14 days after the instillation and subjected to a differential cell count and cytokine measurement. Lung permeability was evaluated as the BAL fluid-to-plasma ratio of the concentration of human serum albumin that was injected 1 h before euthanasia. Nuclear factor (NF)-κB DNA binding activity was also evaluated in lung homogenates. Intratracheal administration of 10 μM or higher concentration of CpG-ODN induced significant inflammatory cell accumulation into the airspace. The peak accumulation of neutrophils and lymphocytes occurred 1 and 2 days after the CpG-ODN administration, respectively. Lung permeability was increased 1 day after the 10 μM CpG-ODN challenge. CpG-ODN also induced nuclear translocation of NF-κB and upregulation of various inflammatory cytokines in BAL fluid and plasma. Histopathology of the lungs and liver revealed acute lung injury and liver damage with necrosis, respectively. Control ODN without CpG motif did not induce any inflammatory change. Since intratracheal CpG-ODN induced acute lung injury as well as systemic inflammatory response, therapeutic strategies to neutralize bacterial DNA that is released after administration of bactericidal agents should be considered
Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies
The aim of this work was to test in vitro and in vivo the efficacy of the derivatives of 5-aminolevulinic acid (ALA): hexyl-ALA (He-ALA), undecanoyl-ALA and R,S-2-(hydroximethyl)tetrahydropyranyl-ALA (THP-ALA) as pro-photosensitising agents. The compounds were assayed in a cell line derived from a murine mammary tumour, in tumour explants and after injection of the cells into mice. In vitro, undecanoyl-ALA and THP-ALA did not improve ALA efficacy in terms of porphyrin synthesis. On the other hand, half of the amount of ALA is required to obtain the same plateau amount of photosensitiser from He-ALA. However, this plateau value cannot be surpassed in spite of the four-times higher accumulation of ALA/He-ALA from the ALA derivative. This shows that He-ALA conversion to porphyrins but not He-ALA entry to the cells is limiting. Employing ionic exchange chromatography, we found that 80% of total uptake was He-ALA whereas only 20% was ALA. This suggests that the esterases, probably themselves regulated by the heme pathway, are limiting the conversion of ALA derivatives into porphyrins. A similar situation occurs with THP-ALA. Tumour explant porphyrin results correlate well with cell line data. However, i.p. injection of ALA derivatives to mice resulted in a lower porphyrin concentration in the tumour when compared to the administration of equimolar amounts of ALA, indicating that there should be retention of ALA derivatives either within the blood vessels in the initial phase of distribution and/or within the capillaries of the tumour. © 2004 Cancer Research UK.Fil: Perotti, C.. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Investigaciones sobre Porfirinas y Porfirias. Universidad de Buenos Aires. Centro de Investigaciones sobre Porfirinas y Porfirias; ArgentinaFil: Fukuda, Haydee. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Investigaciones sobre Porfirinas y Porfirias. Universidad de Buenos Aires. Centro de Investigaciones sobre Porfirinas y Porfirias; ArgentinaFil: Di Venosa, Gabriela Mariana. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Investigaciones sobre Porfirinas y Porfirias. Universidad de Buenos Aires. Centro de Investigaciones sobre Porfirinas y Porfirias; ArgentinaFil: MacRobert, A.J.. No especifÃca;Fil: Batlle, Alcira MarÃa del C.. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Investigaciones sobre Porfirinas y Porfirias. Universidad de Buenos Aires. Centro de Investigaciones sobre Porfirinas y Porfirias; ArgentinaFil: Casas, Adriana Gabriela. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Houssay. Centro de Investigaciones sobre Porfirinas y Porfirias. Universidad de Buenos Aires. Centro de Investigaciones sobre Porfirinas y Porfirias; Argentin
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