German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version)

Psoriasis vulgaris is a common and chronic inflammatory skin disease which has the potential to significantly reduce the quality of life in severely affected patients. The incidence of psoriasis in Western industrialized countries ranges from 1.5 to 2%. Despite the large variety of treatment options available, patient surveys have revealed insufficient satisfaction with the efficacy of available treatments and a high rate of medication non-compliance. To optimize the treatment of psoriasis in Germany, the Deutsche Dermatologische Gesellschaft and the Berufsverband Deutscher Dermatologen (BVDD) have initiated a project to develop evidence-based guidelines for the management of psoriasis. The guidelines focus on induction therapy in cases of mild, moderate, and severe plaque-type psoriasis in adults. The short version of the guidelines reported here consist of a series of therapeutic recommendations that are based on a systematic literature search and subsequent discussion with experts in the field; they have been approved by a team of dermatology experts. In addition to the therapeutic recommendations provided in this short version, the full version of the guidelines includes information on contraindications, adverse events, drug interactions, practicality, and costs as well as detailed information on how best to apply the treatments described (for full version, please see Nast et al., JDDG, Suppl 2:S1–S126, 2006; or http://www.psoriasis-leitlinie.de)

Advanced Implementation Issues of Turbo-Decoders

: This paper presents a new renormalization scheme for Turbo-decoders and a novel early stop criterion which can be used to considerably reduce implementation complexity. Keywords: Turbo-decoder, implementation. 1

German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version)-1

<p><b>Copyright information:</b></p><p>Taken from "German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version)"</p><p></p><p>Archives of Dermatological Research 2007;299(3):111-138.</p><p>Published online Jan 2007</p><p>PMCID:PMC1910890.</p><p></p> options are listed alphabetically and do not represent a ranking

German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version)-0

<p><b>Copyright information:</b></p><p>Taken from "German evidence-based guidelines for the treatment of Psoriasis vulgaris (short version)"</p><p></p><p>Archives of Dermatological Research 2007;299(3):111-138.</p><p>Published online Jan 2007</p><p>PMCID:PMC1910890.</p><p></p> options are listed alphabetically and do not represent a ranking

Transonic aeroelastic simulation for instability searches and uncertainty analysis

In this paper the use of eigenvalue stability analysis of very large dimension aeroelastic numerical models arising from the exploitation of computational fluid dynamics is reviewed. A formulation based on a block reduction of the system Jacobian proves powerful to allow various numerical algorithms to be exploited, including frequency domain solvers, reconstruction of a term describing the fluid–structure interaction from the sparse data which incurs the main computational cost, and sampling to place the expensive samples where they are most needed. The stability formulation also allows non-deterministic analysis to be carried out very efficiently through the use of an approximate Newton solver. Finally, the system eigenvectors are exploited to produce nonlinear and parameterised reduced order models for computing limit cycle responses. The performance of the methods is illustrated with results from a number of academic and large dimension aircraft test cases