Covariant Hamiltonian Dynamics with Negative Energy States

A relativistic quantum mechanics is studied for bound hadronic systems in the framework of the Point Form Relativistic Hamiltonian Dynamics. Negative energy states are introduced taking into account the restrictions imposed by a correct definition of the Poincar\'e group generators. We obtain nonpathological, manifestly covariant wave equations that dynamically contain the contributions of the negative energy states. Auxiliary negative energy states are also introduced, specially for studying the interactions of the hadronic systems with external probes.Comment: 42 pages, submitted to EPJ

Effects due to a scalar coupling on the particle-antiparticle production in the Duffin-Kemmer-Petiau theory

The Duffin-Kemmer-Petiau formalism with vector and scalar potentials is used to point out a few misconceptions diffused in the literature. It is explicitly shown that the scalar coupling makes the DKP formalism not equivalent to the Klein-Gordon formalism or to the Proca formalism, and that the spin-1 sector of the DKP theory looks formally like the spin-0 sector. With proper boundary conditions, scattering of massive bosons in an arbitrary mixed vector-scalar square step potential is explored in a simple way and effects due to the scalar coupling on the particle-antiparticle production and localization of bosons are analyzed in some detail

Testing of CP, CPT and causality violation with the light propagation in vacuum in presence of the uniform electric and magnetic fields

We have considered the structure of the fundamental symmetry violating part of the photon refractive index in vacuum in the presence of constant electric and magnetic fields. This part of the refractive index can, in principle, contain CPT symmetry breaking terms. Some of the terms violate Lorentz invariance, whereas the others violate locality and causality. Estimates of these effects, using laser experiments are considered.Comment: 12 page

On Equivalence of Duffin-Kemmer-Petiau and Klein-Gordon Equations

A strict proof of equivalence between Duffin-Kemmer-Petiau (DKP) and Klein-Gordon (KG) theories is presented for physical S-matrix elements in the case of charged scalar particles interacting in minimal way with an external or quantized electromagnetic field. First, Hamiltonian canonical approach to DKP theory is developed in both component and matrix form. The theory is then quantized through the construction of the generating functional for Green functions (GF) and the physical matrix elements of S-matrix are proved to be relativistic invariants. The equivalence between both theories is then proved using the connection between GF and the elements of S-matrix, including the case of only many photons states, and for more general conditions - so called reduction formulas of Lehmann, Symanzik, Zimmermann.Comment: 23 pages, no figures, requires macro tcilate

Semi-relativistic charge-current density operator

The charge-current density and two-photon operators consistent with a single-particle semi-relativistic Hamiltonian are derived within a suitable functional derivative formalism which preserves gauge invariance. An application to electron scattering is presented and results are compared with a fully relativistic case and the non-relativistic cases corrected through fourth order in M^{-1}.Comment: 20 pages, 3 postscript figures, typos correcte

Exact Solution of Photon Equation in Stationary G\"{o}del-type and G\"{o}del Space-Times

In this work the photon equation (massless Duffin-Kemmer-Petiau equation) is written expilicitly for general type of stationary G\"{o}del space-times and is solved exactly for G\"{o}del-type and G\"{o}del space-times. Harmonic oscillator behaviour of the solutions is discussed and energy spectrum of photon is obtained.Comment: 9 pages,RevTeX, no figure, revised for publicatio

Poincare' invariance and the heavy-quark potential

We derive and discuss the constraints induced by Poincare' invariance on the form of the heavy-quark potential up to order 1/m^2. We present two derivations: one uses general arguments directly based on the Poincare' algebra and the other follows from an explicit calculation on the expression of the potential in terms of Wilson loops. We confirm relations from the literature, but also clarify the origin of a long-standing false statement pointed out recently.Comment: 20 pages, 4 figure

Spin 1 fields in Riemann-Cartan space-times "via" Duffin-Kemmer-Petiau theory

We consider massive spin 1 fields, in Riemann-Cartan space-times, described by Duffin-Kemmer-Petiau theory. We show that this approach induces a coupling between the spin 1 field and the space-time torsion which breaks the usual equivalence with the Proca theory, but that such equivalence is preserved in the context of the Teleparallel Equivalent of General Relativity.Comment: 8 pages, no figures, revtex. Dedicated to Professor Gerhard Wilhelm Bund on the occasion of his 70th birthday. To appear in Gen. Rel. Grav. Equations numbering corrected. References update

Design of Cationic Multi-Walled Carbon Nanotubes as Efficient siRNA Vectors for Lung Cancer Xenograft Eradication

Polo-Like Kinase (PLK1) has been identified as a potential target in cancer gene therapy via chemical or genetic inhibitory approaches. The biomedical applications of chemically functionalized carbon nanotubes (f-CNTs) in cancer therapy have been studied due to their ability to efficiently deliver siRNA intracellularly. In this study, we established the capacity of cationic MWNT-NH3+ to deliver the apoptotic siRNA against PLK1 (siPLK1) in Calu6 tumor xenografts by direct intratumoural injections. A direct comparison with cationic liposomes was made. This study validates the PLK1 gene as a potential target in cancer gene therapy including lung cancer, as demonstrated by the therapeutic efficacy of siPLK1:MWNT-NH3+ complexes and their ability to significantly improve animal survival. Biological analysis of the siPLK1:MWNT-NH3+ treated tumors by RT-PCR and Western blot, in addition to TUNEL staining confirmed the biological functionality of the siRNA intratumourally, suggesting that tumor eradication was due to PLK1 knockdown. Furthermore, by using a fluorescently labelled, non-coding siRNA sequence complexed with MWNT-NH3+, we established for the first time that the improved therapeutic efficacy observed in f-CNT-based siRNA delivery is directly proportional to the enhanced siRNA retention in the solid tumor and subsequent uptake by tumor cells after local administration in vivo

Generalized dipole polarizabilities and the spatial structure of hadrons

We present a phenomenological discussion of spin-independent, generalized dipole polarizabilities of hadrons entering the virtual Compton scattering process gamma* h -> gamma h. We introduce a new method of obtaining a tensor basis with appropriate Lorentz-invariant amplitudes which are free from kinematical singularities and constraints. We then motivate a gauge-invariant separation into a generalized Born term containing ground-state properties only, and a residual contribution describing the model-dependent internal structure. The generalized dipole polarizabilities are defined in terms of Lorentz-invariant residual amplitudes. Particular emphasis is laid on a physical interpretation of these quantities as characterizing the spatial distributions of the induced electric polarization and magnetization of hadrons. It is argued that three dipole polarizabilities, namely the longitudinal electric alpha_L(q^2), the transverse electric alpha_T(q^2), and the magnetic beta(q^2) ones are required in order to fully reconstruct local polarizations induced by soft external fields in a hadron. One of these polarizabilities, alpha_T(q^2), describes an effect of higher order in the soft final-photon momentum q'. We argue that the associated spatial distributions obtained via the Fourier transforms in the Breit frame are meaningful even for such a light particle as the pion. The spatial distributions are determined at large distances r ~ 1/m_pi for pions, kaons, and octet baryons by use of ChPT.Comment: 41 pages, 5 figures, RevTex fil