517 research outputs found
From foreigners to citizens : conceptualising students' entry into disciplinary communities of practice
CITATION: Young, G. & Kotze, A. 2009. From foreigners to citizens : conceptualising students' entry into disciplinary communities of practice. Akroterion, 54:125-139, doi:10.7445/54-0-31.The original publication is available at http://akroterion.journals.ac.zaThe discipline of Classics, like most other disciplines in Higher Education
contexts, faces numerous challenges related to changed national and
international expectations. This article argues that in order to meet these
challenges the discipline needs to reflect on its activities and teaching practices
in a structured and deliberate way. Such reflection can be facilitated by
theoretical frameworks designed in education research. We present one such
framework, the “Communities of practice” as designed by Wenger (1998) and
show how the framework can be employed, at a theoretical level, to
conceptualise the challenges facing the discipline as well as to enhance teaching
practices in an undergraduate Greek class, through an institutionally supported
project. By applying this framework educators can assist students both in
preparing for their careers as well as in engaging with their studies.http://akroterion.journals.ac.za/pub/article/view/31Publisher's versio
The Effect of Egg Embryonation on Field-Use of a Hookworm Benzimidazole-Sensitivity Egg Hatch Assay in Yunnan Province, People's Republic of China
With the implementation of mass drug administration programmes for the control of human soil transmitted helminths there is a need to develop drug sensitivity monitoring tools to detect the emergence of resistance. The present study aimed to use an egg hatch assay to measure benzimidazole sensitivity in human hookworms in a field setting in Yunnan province, People's Republic of China, in order to assess whether the assay offered a practical means of monitoring drug sensitivity in human hookworms in such a location. The assay proved able to generate dose response data, which allowed for the drug sensitivity of the hookworms in the local children to be described; the mean IC50 was 0.10 ug/ml thiabendazole. The study also found that practical issues associated with stool collection procedures, specifically the embryonation of some eggs during the time elapsing between stool deposition and egg recovery, can have an impact on the drug sensitivity data. We suggest means for data analysis that overcome the impact of egg embryonation on drug dose response data, which should allow for the use of such assays at different field sites worldwide
Conservation Laws in Cellular Automata
If X is a discrete abelian group and B a finite set, then a cellular
automaton (CA) is a continuous map F:B^X-->B^X that commutes with all X-shifts.
If g is a real-valued function on B, then, for any b in B^X, we define G(b) to
be the sum over all x in X of g(b_x) (if finite). We say g is `conserved' by F
if G is constant under the action of F. We characterize such `conservation
laws' in several ways, deriving both theoretical consequences and practical
tests, and provide a method for constructing all one-dimensional CA exhibiting
a given conservation law.Comment: 19 pages, LaTeX 2E with one (1) Encapsulated PostScript figure. To
appear in Nonlinearity. (v2) minor changes/corrections; new references added
to bibliograph
Helicobacter pylori prevalence in non-ulcer dyspepsia ethnic and socio-economic differences
Helicobacter pylori is an important cause of gastritis and a number of therapeutic. trials suggest that it may be important in the genesis of duodenal ulcer recurrence. The reported prevalence of gastric colonisation by the organism varies considerably. The aiIn of this cross-sectional survey was to determine its prevalence in non-ulcer dyspeptics and to determine whether this is influenced by age, race, sex, socio-economic status, educational level and the nwnber of persons sharing accommodation. One hundred and sixty-nine patients underwent endoscopy; biopsy speciInens were taken from the antrwn and H. pylori status was determined histologically. Gastric colonisation was found in 106 patients (63%). The prevalence showed a marked ethnic difference: 40% in whites and 71% in coloureds (P < 0,001). The ethnic groups were characterised by significant differences in socio-economic status (P < 10-6), educational level (P < 10-6), number of persons sharing accommodation (P < 10-6 ) and age (P < 0,001). These same differences were found when comparing the H. pylori-positive and negative groups, but were less marked and could be attributed to the marked differences between ethnic groups. We conclude that H. pylori prevalence differs between the ethnic groups studied. This may be because of varying degrees of exposure risk
A Novel High Throughput Assay for Anthelmintic Drug Screening and Resistance Diagnosis by Real-Time Monitoring of Parasite Motility
Parasitic worms cause untold morbidity and mortality on billions of people and livestock. Drugs are available but resistance is problematic in livestock parasites and is a looming threat for human helminths. Currently, new drug discovery and resistance monitoring is hindered as drug efficacy is assessed by observing motility or development of parasites using laborious, subjective, low-throughput methods evaluated by eye using microscopy. Here we describe a novel application for a cell monitoring device (xCELLigence) that can simply and objectively assess real time anti-parasite efficacy of drugs on eggs, larvae and adults in a fully automated, label-free, high-throughput fashion. This technique overcomes the current low-throughput bottleneck in anthelmintic drug development and resistance detection pipelines. The widespread use of this device to screen for new therapeutics or emerging drug resistance will be an invaluable asset in the fight against human, animal and plant parasitic helminths and other pathogens that plague our planet
IGR J19552+0044: A new asynchronous short period polar: "Filling the gap between intermediate and ordinary polars"
Based on XMM--Newton X-ray observations IGR J19552+0044 appears to be either
a pre-polar or an asynchronous polar. We conducted follow-up optical
observations to identify the sources and periods of variability precisely and
to classify this X-ray source correctly. Extensive multicolor photometric and
medium- to high-resolution spectroscopy observations were performed and period
search codes were applied to sort out the complex variability of the object. We
found firm evidence of discording spectroscopic (81.29+/-0.01m) and photometric
(83.599+/-0.002m) periods that we ascribe to the white dwarf (WD)\ spin period
and binary orbital period, respectively. This confirms that IGR J19552+0044 is
an asynchronous polar. Wavelength-dependent variability and its continuously
changing shape point at a cyclotron emission from a magnetic WD with a
relatively low magnetic field below 20 MG.
The difference between the WD spin period and the binary orbital period
proves that IGR J19552+0044 is a polar with the largest known degree of
asynchronism (0.97 or 3%).Comment: 9 pages, 10 figures, A&A accepte
The Genetic Structure and History of Africans and African Americans.
Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, four African American populations, and 60 non-African populations for patterns of variation at 1327 nuclear microsatellite and insertion/deletion markers. We identified 14 ancestral population clusters in Africa that correlate with self-described ethnicity and shared cultural and/or linguistic properties. We observed high levels of mixed ancestry in most populations, reflecting historical migration events across the continent. Our data also provide evidence for shared ancestry among geographically diverse hunter-gatherer populations (Khoesan speakers and Pygmies). The ancestry of African Americans is predominantly from Niger-Kordofanian (approximately 71%), European (approximately 13%), and other African (approximately 8%) populations, although admixture levels varied considerably among individuals. This study helps tease apart the complex evolutionary history of Africans and African Americans, aiding both anthropological and genetic epidemiologic studies
Urban forest invertebrates : how they shape and respond to the urban environment
Invertebrates comprise the most diversified animal group on Earth. Due to their long evolutionary history and small size, invertebrates occupy a remarkable range of ecological niches, and play an important role as "ecosystem engineers" by structuring networks of mutualistic and antagonistic ecological interactions in almost all terrestrial ecosystems. Urban forests provide critical ecosystem services to humans, and, as in other systems, invertebrates are central to structuring and maintaining the functioning of urban forests. Identifying the role of invertebrates in urban forests can help elucidate their importance to practitioners and the public, not only to preserve biodiversity in urban environments, but also to make the public aware of their functional importance in maintaining healthy greenspaces. In this review, we examine the multiple functional roles that invertebrates play in urban forests that contribute to ecosystem service provisioning, including pollination, predation, herbivory, seed and microorganism dispersal and organic matter decomposition, but also those that lead to disservices, primarily from a public health perspective, e.g., transmission of invertebrate-borne diseases. We then identify a number of ecological filters that structure urban forest invertebrate communities, such as changes in habitat structure, increased landscape imperviousness, microclimatic changes and pollution. We also discuss the complexity of ways that forest invertebrates respond to urbanisation, including acclimation, local extinction and evolution. Finally, we present management recommendations to support and conserve viable and diverse urban forest invertebrate populations into the future.Peer reviewe
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