8 research outputs found
Development and validation of a computational model of the knee joint for the evaluation of surgical treatments for osteoarthritis
A three-dimensional (3D) knee joint computational model was developed and validated to predict knee joint contact forces
and pressures for different degrees of malalignment. A 3D computational knee model was created from high-resolution
radiological images to emulate passive sagittal rotation (full-extension to 658-flexion) and weight acceptance. A cadaveric
knee mounted on a six-degree-of-freedom robot was subjected to matching boundary and loading conditions. A ligamenttuning
process minimised kinematic differences between the robotically loaded cadaver specimen and the finite element
(FE) model. The model was validated by measured intra-articular force and pressure measurements. Percent full scale error
between FE-predicted and in vitro-measured values in the medial and lateral compartments were 6.67% and 5.94%,
respectively, for normalised peak pressure values, and 7.56% and 4.48%, respectively, for normalised force values. The knee
model can accurately predict normalised intra-articular pressure and forces for different loading conditions and could be
further developed for subject-specific surgical planning