Abnormal Behavior of ZrO[2]-MgO Porous Ceramic Composite under Compression

In this work ZrO[2]-MgO porous ceramic composite fine crystalline structure was studied, its microstructure and mechanical properties after sintering at 1600°С. Pores had a bimodal size distribution with the mean sizes of about 30 and 100 [mu]m. It was shown that the introduction of organic pore-forming particles into the initial powder composition of ZrO[2]-MgO allows producing ceramics with a bimodal pore structure, the material strength is mainly determined by microstresses, and in general, such porous ceramics show uncharacteristic behavior under compression, which is confirmed by plot of the Hall-Petch dependence of microstresses on the average crystallite size with the coefficient K=0.38 MPa m{1/2}, corresponding to plastic materials

Toward high-resolution population genomics using archaeological samples

The term ‘ancient DNA’ (aDNA) is coming of age, with over 1,200 hits in the PubMed database, beginning in the early 1980s with the studies of ‘molecular paleontology’. Rooted in cloning and limited sequencing of DNA from ancient remains during the pre-PCR era, the field has made incredible progress since the introduction of PCR and next-generation sequencing. Over the last decade, aDNA analysis ushered in a new era in genomics and became the method of choice for reconstructing the history of organisms, their biogeography, and migration routes, with applications in evolutionary biology, population genetics, archaeogenetics, paleoepidemiology, and many other areas. This change was brought by development of new strategies for coping with the challenges in studying aDNA due to damage and fragmentation, scarce samples, significant historical gaps, and limited applicability of population genetics methods. In this review, we describe the state-of-the-art achievements in aDNA studies, with particular focus on human evolution and demographic history. We present the current experimental and theoretical procedures for handling and analysing highly degraded aDNA. We also review the challenges in the rapidly growing field of ancient epigenomics. Advancement of aDNA tools and methods signifies a new era in population genetics and evolutionary medicine research

Difficulties of Educating People With Socio-Educational Needs

The publication “Problems of introducing inclusive education in the social environment of Ussuriysk city” examines the complex problems and sociocultural processes of society concerning people with special socio-educational needs, people with disabilities and people with physical disabilities. The paper briefly explains the essence of inclusive education and the problems of its introduction into the social environment of small towns, for example, the city of Ussuriysk, when, along with the development of defectological schools and the government order for them, there is a lack of understanding of the need for such education, an indifferent, callous attitude towards disadvantaged physical disabilities to people.The publication “Problems of introducing inclusive education in the social environment of Ussuriysk city” examines the complex problems and sociocultural processes of society concerning people with special socio-educational needs, people with disabilities and people with physical disabilities. The paper briefly explains the essence of inclusive education and the problems of its introduction into the social environment of small towns, for example, the city of Ussuriysk, when, along with the development of defectological schools and the government order for them, there is a lack of understanding of the need for such education, an indifferent, callous attitude towards disadvantaged physical disabilities to people

Arctic climate policy development: taking public beliefs into account

For the effective implementation of climate policy in the Arctic, public beliefs must be taken into account in its development. The research presented in this report shows that the majority are inclined to believe that climate change is occurring, where the younger generation associates these changes with anthropogenic impact, while the older respondents with natural causes. The majority are confident that climate change in the Russian Arctic will bring positive change, increase the standard of living in the Arctic, improve conditions for farming, and increase the intensity of traffic along the Northern Sea Route. Thus, the population is not ready to bear the possible costs when the climate policy is tightened; people’s expectations are aimed at increasing the comfort of living in the Arctic

Dificultades para educar a las personas con necesidades socioeducativas

The publication “Problems of introducing inclusive education in the social environment of Ussuriysk city” examines the complex problems and sociocultural processes of society concerning people with special socio-educational needs, people with disabilities and people with physical disabilities. The paper briefly explains the essence of inclusive education and the problems of its introduction into the social environment of small towns, for example, the city of Ussuriysk, when, along with the development of defectological schools and the government order for them, there is a lack of understanding of the need for such education, an indifferent, callous attitude towards disadvantaged physical disabilities to people.Este estudio examinalos problemas complejos y los procesos socioculturales de la sociedad en relación con las personas con necesidades socioeducativas especiales, las personas con discapacidad y las personas con discapacidad física. El documento explica brevemente la esenciade la educación inclusiva y los problemas de su introducción en el entorno social de los pueblos pequeños, por ejemplo, la ciudad de Ussuriysk, cuando, junto con el desarrollo de escuelas defectológicas y el orden del gobierno para ellos, existe una faltade comprensión de la necesidad de tal educación, una actitud indiferente e insensible hacia las personas con discapacidades físicas desfavorecidas

Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation

Donor killer immunoglobulin-like receptor (KIR) genotypes are associated with relapse protection and survival after allotransplantation for acute myelogenous leukemia. We examined the possibility of a similar effect in a cohort of 614 non-Hodgkin lymphoma (NHL) patients receiving unrelated donor (URD) T cell-replete marrow or peripheral blood grafts. Sixty-four percent (n = 396) of donor-recipient pairs were 10/10 allele HLA matched and 26% were 9/10 allele matched. Seventy percent of donors had KIR B/x genotype; the others had KIR A/A genotype. NHL patients receiving 10/10 HLA-matched URD grafts with KIR B/x donors experienced significantly lower relapse at 5 years (26%; 95% confidence interval [CI], 21% to 32% versus 37%; 95% CI, 27% to 46%; P = .05) compared with KIR A/A donors, resulting in improved 5-year progression-free survival (PFS) (35%; 95% CI, 26% to 44% versus 22%; 95% CI, 11% to 35%; P = .007). In multivariate analysis, use of KIR B/x donors was associated with significantly reduced relapse risk (relative risk [RR], .63, P = .02) and improved PFS (RR, .71, P = .008). The relapse protection afforded by KIR B/x donors was not observed in HLA-mismatched transplantations and was not specific to any particular KIR-B gene. Selecting 10/10 HLA-matched and KIR B/x donors should benefit patients with NHL receiving URD allogeneic transplantation

Определение производительности модулей нового универсального сушильного агрегата

Drying of seed material plays an important part in the system of post-harvest processing and greatly affects the yield quality of the seed material. (Research purpose) Determination of the performance of two modules of a new dryer, taking into account the statistical characteristics of humidity, impurity content and the intensity of submitting the grain heap of various crops to post-harvest processing. (Materials and methods) The research group has tested a mini-module of a new universal dryer developed in the laboratory workshops of Yaroslavl State Agricultural Academy, in the Bolshoye Selo district of the Yaroslavl region. The calculation has been based on the data of the average regional farm. (Results and discussion) It has been determined that the average statistical percentage of moisture removal from the original grain heap was 10.52 percent; gross grain harvest per year – 1,500 tons; the estimated capacity by the dried seed material of the base module is 5 tons per hour, that of the mini module - 0.35 tons per hour. Due to the contribution of Yaroslavl State Agricultural Academy, fully mechanized receiving chambers with air chutes accommodating 300 or 600 cubic meters of heap coming from combines have been introduced into the production lines of post-harvest processing of the crop material. The efficiency calculation of the mini-module has been caused by the need to use it on the farms for the independent supply of high-quality seed material. (Conclusions) The experiment results have confirmed the validity of the calculations and the effectiveness of the new method of drying. In unfavorable weather, grain crops were harvested by a forage harvester and then dried in a mini-module. After processing, high-quality seeds were obtained, the germination rate of which accounted 98-99 percent.Сушка семенного материала занимает важное место в системе его послеуборочной обработки и в значительной степени влияет на урожайные качества посевного материала. (Цель исследования) Определение производительности двух модулей новой сушилки с учетом статистических характеристик влажности, засоренности и интенсивности поступления на послеуборочную обработку зернового вороха различных культур. (Материалы и методы) Провели испытания мини-модуля новой универсальной сушилки, разработанного в мастерских Ярославской государственной сельскохозяйственной академии, в Большесельском районе Ярославской области. За основу расчета взяты данные среднестатистического областного хозяйства. (Результаты и обсуждение) Определили, что средний статистический процент влагосъема у исходного зернового вороха составил 10,52 процента; валовой сбор зерна за год – 1500 тонн; расчетная производительность по высушенному семенному материалу у базового модуля равна 5 тонн в час, у мини-модуля – 0,35 тонны в час. С участием Ярославской ГСХА в поточные линии послеуборочной обработки урожая внедрены полностью механизированные приемные отделения с аэрожелобами, вмещающие 300 или 600 кубических метров зернового вороха, поступающего от комбайнов. Расчет эффективности мини-модуля обусловлен необходимостью использования его в хозяйствах для самостоятельного обеспечения высококачественным посевным материалом. (Выводы) Подтвердили обоснованность расчетов и эффективность нового способа сушки. В неблагоприятную погоду урожай зерновых культур убирали кормоуборочным комбайном, сушили в мини-модуле. После обработки получили высококачественные семена, всхожесть которых составила 98-99 процентов

Creation of the Simplest 3d Models for Additional Educatiоn

Introduction. This article describes the features of the TinkerCAD program that are specific to creating 3D models. The ability of a computer to reproduce information simultaneously in the form of a graphic image, text, speech, sound, video, remember and process data at a high speed allows specialists to create new activities for children; and therefore it is necessary to introduce information technologies into the system of initial education and training. The practical experience has proved that children’s motivation to study is growing fast, and the level of cognitive abilities is increasing too. Information technologies provide a personal-oriented approach, the capabilities of the computer allow to increase the volume of the offered material for familiarization. In addition, schoolchildren have the same program material to repeat and many forms of material presentation are of great importance. Technologies used in the organization of additional training in IT-technology lessons should be aimed at activity approach. This will help to differentiate students and help them to adequately evaluate themselves without affecting their self-esteem. The basis for conducting classes may be design and research technologies, which ensure the systematic immersion of the child into the process of independent construction of new knowledge and allow to carry out training of different levels. The aim of the article is to present and summarize the possibilities of using 3D models in the secondary school education space. Methodology and methods are based on the analysis of psychology and pedagogical, scientific and methodical, popular scientific and educational literature, Internet sources; surveillance, interviews with students and teachers; monitoring and analyzing the activities of teachers and students with a view to studying the state of the problem under study. Results. Innovative methods and methods of teaching in the field of 3D modeling and their influence on practical work of students have been studied. Scientific novelty. The possibilities of 3D modeling in the field of additional education were analyzed. Practical importance. 3D objects have been investigated, in particular the program is TinkerCAD as a technology of additional education