306 research outputs found

    Difficulties of Educating People With Socio-Educational Needs

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    The publication “Problems of introducing inclusive education in the social environment of Ussuriysk city” examines the complex problems and sociocultural processes of society concerning people with special socio-educational needs, people with disabilities and people with physical disabilities. The paper briefly explains the essence of inclusive education and the problems of its introduction into the social environment of small towns, for example, the city of Ussuriysk, when, along with the development of defectological schools and the government order for them, there is a lack of understanding of the need for such education, an indifferent, callous attitude towards disadvantaged physical disabilities to people.The publication “Problems of introducing inclusive education in the social environment of Ussuriysk city” examines the complex problems and sociocultural processes of society concerning people with special socio-educational needs, people with disabilities and people with physical disabilities. The paper briefly explains the essence of inclusive education and the problems of its introduction into the social environment of small towns, for example, the city of Ussuriysk, when, along with the development of defectological schools and the government order for them, there is a lack of understanding of the need for such education, an indifferent, callous attitude towards disadvantaged physical disabilities to people

    Arctic climate policy development: taking public beliefs into account

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    For the effective implementation of climate policy in the Arctic, public beliefs must be taken into account in its development. The research presented in this report shows that the majority are inclined to believe that climate change is occurring, where the younger generation associates these changes with anthropogenic impact, while the older respondents with natural causes. The majority are confident that climate change in the Russian Arctic will bring positive change, increase the standard of living in the Arctic, improve conditions for farming, and increase the intensity of traffic along the Northern Sea Route. Thus, the population is not ready to bear the possible costs when the climate policy is tightened; people’s expectations are aimed at increasing the comfort of living in the Arctic

    Dificultades para educar a las personas con necesidades socioeducativas

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    The publication “Problems of introducing inclusive education in the social environment of Ussuriysk city” examines the complex problems and sociocultural processes of society concerning people with special socio-educational needs, people with disabilities and people with physical disabilities. The paper briefly explains the essence of inclusive education and the problems of its introduction into the social environment of small towns, for example, the city of Ussuriysk, when, along with the development of defectological schools and the government order for them, there is a lack of understanding of the need for such education, an indifferent, callous attitude towards disadvantaged physical disabilities to people.Este estudio examinalos problemas complejos y los procesos socioculturales de la sociedad en relación con las personas con necesidades socioeducativas especiales, las personas con discapacidad y las personas con discapacidad física. El documento explica brevemente la esenciade la educación inclusiva y los problemas de su introducción en el entorno social de los pueblos pequeños, por ejemplo, la ciudad de Ussuriysk, cuando, junto con el desarrollo de escuelas defectológicas y el orden del gobierno para ellos, existe una faltade comprensión de la necesidad de tal educación, una actitud indiferente e insensible hacia las personas con discapacidades físicas desfavorecidas

    Определение производительности модулей нового универсального сушильного агрегата

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    Drying of seed material plays an important part in the system of post-harvest processing and greatly affects the yield quality of the seed material. (Research purpose) Determination of the performance of two modules of a new dryer, taking into account the statistical characteristics of humidity, impurity content and the intensity of submitting the grain heap of various crops to post-harvest processing. (Materials and methods) The research group has tested a mini-module of a new universal dryer developed in the laboratory workshops of Yaroslavl State Agricultural Academy, in the Bolshoye Selo district of the Yaroslavl region. The calculation has been based on the data of the average regional farm. (Results and discussion) It has been determined that the average statistical percentage of moisture removal from the original grain heap was 10.52 percent; gross grain harvest per year – 1,500 tons; the estimated capacity by the dried seed material of the base module is 5 tons per hour, that of the mini module - 0.35 tons per hour. Due to the contribution of Yaroslavl State Agricultural Academy, fully mechanized receiving chambers with air chutes accommodating 300 or 600 cubic meters of heap coming from combines have been introduced into the production lines of post-harvest processing of the crop material. The efficiency calculation of the mini-module has been caused by the need to use it on the farms for the independent supply of high-quality seed material. (Conclusions) The experiment results have confirmed the validity of the calculations and the effectiveness of the new method of drying. In unfavorable weather, grain crops were harvested by a forage harvester and then dried in a mini-module. After processing, high-quality seeds were obtained, the germination rate of which accounted 98-99 percent.Сушка семенного материала занимает важное место в системе его послеуборочной обработки и в значительной степени влияет на урожайные качества посевного материала. (Цель исследования) Определение производительности двух модулей новой сушилки с учетом статистических характеристик влажности, засоренности и интенсивности поступления на послеуборочную обработку зернового вороха различных культур. (Материалы и методы) Провели испытания мини-модуля новой универсальной сушилки, разработанного в мастерских Ярославской государственной сельскохозяйственной академии, в Большесельском районе Ярославской области. За основу расчета взяты данные среднестатистического областного хозяйства. (Результаты и обсуждение) Определили, что средний статистический процент влагосъема у исходного зернового вороха составил 10,52 процента; валовой сбор зерна за год – 1500 тонн; расчетная производительность по высушенному семенному материалу у базового модуля равна 5 тонн в час, у мини-модуля – 0,35 тонны в час. С участием Ярославской ГСХА в поточные линии послеуборочной обработки урожая внедрены полностью механизированные приемные отделения с аэрожелобами, вмещающие 300 или 600 кубических метров зернового вороха, поступающего от комбайнов. Расчет эффективности мини-модуля обусловлен необходимостью использования его в хозяйствах для самостоятельного обеспечения высококачественным посевным материалом. (Выводы) Подтвердили обоснованность расчетов и эффективность нового способа сушки. В неблагоприятную погоду урожай зерновых культур убирали кормоуборочным комбайном, сушили в мини-модуле. После обработки получили высококачественные семена, всхожесть которых составила 98-99 процентов

    Интеграция общества как необходимый объект государственной политики в РФ

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    Статья посвящена теме интеграции современного Российского общества. Она проходит через основные социальные системы: семью, кооперацию, рынок, ассоциации, общности. Уровень интеграции в обществе – величина переменная и она имеет свое оптимальное значение на каждом уровне его развития. Для этого в РФ необходимо сформировать специальный управленческий орган. The article is devoted to the topic of the integration of modern Russian society. It passes through major social systems: family, cooperation, market, Association, community. The level of integration in society is variable and it has its optimalnoe value at each level of its development. To do this, in Russia it is necessary to form a special administrative body

    Molecular Diagnostics, Targeted Therapy, and the Indication for Allogeneic Stem Cell Transplantation in Acute Lymphoblastic Leukemia

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    In recent years, the panel of known molecular mutations in acute lymphoblastic leukemia (ALL) has been continuously increased. In Philadelphia-positive ALL, deletions of the IKZF1 gene were identified as prognostically adverse factors. These improved insights in the molecular background and the clinical heterogeneity of distinct cytogenetic subgroups may allow most differentiated therapeutic decisions, for example, with respect to the indication to allogeneic HSCT within genetically defined ALL subtypes. Quantitative real-time PCR allows highly sensitive monitoring of the minimal residual disease (MRD) load, either based on reciprocal gene fusions or immune gene rearrangements. Molecular diagnostics provided the basis for targeted therapy concepts, for example, combining the tyrosine kinase inhibitor imatinib with chemotherapy in patients with Philadelphia-positive ALL. Screening for BCR-ABL1 mutations in Philadelphia-positive ALL allows to identify patients who may benefit from second-generation tyrosine kinase inhibitors or from novel compounds targeting the T315I mutation. Considering the central role of the molecular techniques for the management of patients with ALL, efforts should be made to facilitate and harmonize immunophenotyping, cytogenetics, and molecular mutation screening. Furthermore, the potential of high-throughput sequencing should be evaluated for diagnosis and follow-up of patients with B-lineage ALL

    The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients

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    Despite the favorable prognosis of most patients with Hodgkin's Lymphoma (HL), 15–20% of patients remain refractory to chemoradiotherapy, and 20–40% experience relapses following autologous stem cell transplantation (SCT) being used as salvage approach in this situation. Long-term survival of only 20% was reported for patients who failed this option. As some authors suggested the presence of a graft versus HL effect, allogeneic SCT was introduced as a further option. Myeloablative strategies were reported to be able to achieve cure in some younger patients, but high nonrelapse mortality remains a problem. Reduced intensity conditioning, in turn, was found to be associated with high posttransplant relapse rates. As there is currently no standard in the management of HL patients who failed autologous SCT, we here review the literature on allogeneic stem cell transplantation in HL patients with a special focus on the outcomes and risk factors being reported in the largest studies
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