217 research outputs found

    The ultimate arc: Differential displacement, oroclinal bending, and vertical axis rotation in the External Betic-Rif arc

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    The External Betic-Rif arc, which lies between the converging African and Iberian plates, is one of the tightest orogenic arcs on Earth. It is a thin-skinned fold and thrust belt formed in Miocene time around the periphery of the Alborán Domain, an older contractional orogen that underwent extensional collapse coevally with the formation of the thrust belt. Restoration of four sections across the thrust belt, together with kinematic and paleomagnetic analysis, allows a reconstruction of the prethrusting geometry of the Alborán Domain, and the identification of the following processes that contributed to the formation of the arc: (1) The Alborán Domain moved some 250 km westward relative to Iberia and Africa during the Miocene. This initiated the two limbs of the arc on its NW and SW margins, closing to the WSW in the region of Cherafat in northern Morocco. The overall convergence direction on the Iberian side of the arc was between 310° and 295°, and on the African side it was between 235° and 215°. The difference in convergence direction between the two sectors was primarily a result of the relative motion between Africa and Iberia. (2) Extensional collapse of the Alborán Domain during the Miocene modified the geometry of the western end of the arc: the Internal Rif rotated anticlockwise to form the present north trending sector of the arc, and additional components of displacement produced by extension were transferred into the external thrust belt along a series of strike-slip faults and shear zones. These allowed the limbs of the arc to rotate and extend, tightening the arc, and creating variations in the amounts and directions of shortening around the arc. The Betic sector of the arc rotated clockwise by 25° during this process, and the southern Rif rotated anticlockwise by ∼55°. (3) Oblique convergence on the two limbs of the arc, dextral in the Betics and sinistral in the southern Rif, resulted in strongly noncoaxial deformation. This had three related effects: (1) large rotations of individual thrust sheets resulted from the oblique propagation of thrusts away from the thrust front, followed by pinning and rotation as the thrust sheets peeled off, (2) continued oblique convergence resulted in distributed shear, particularly in the rear of the thrust wedge, causing rotation of stacks of thrust sheets on the scale of a few tens of kilometers, and (3) distributed shear in the orogen resulted in the rotation of folds as they amplified, the hinges migrating through the rock body, and rotating at a slower rate than the rock. These rotations were substantially larger than the bulk rotations of the limbs of the arc, and they strongly modified the orientations of folds, thrust traces, and the structural indicators of fault slip directions

    DURABILITY OF MASS TIMBER STRUCTURES: A REVIEW OF THE BIOLOGICAL RISKS

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    Mass timber structures have the potential to change wooden construction on a global scale. Numerous mass timber high-rise buildings are in planning, under development or already built and their performance will alter how architects and engineers view wood as a material. To date, the discussion of material durability and biodegradation in these structures has been limited. While all materials can be degraded by wetting, the potential for biodegradation of wood in a mass timber building requires special consideration. Identifying and eliminating the conditions that might lead to this degradation will be critical for ensuring proper performance of wood in these structures. This article reviews and contrasts potential sources of biodegradation that exist for traditional wood construction with those in mass timber construction and identifies methods for limiting the degradation risk. Finally, future research needs are outlined

    A Personalized Self-Management Rehabilitation System for Stroke Survivors: A Quantitative Gait Analysis Using a Smart Insole.

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    Background: In the United Kingdom, stroke is the single largest cause of adult disability and results in a cost to the economy of £8.9 billion per annum. Service needs are currently not being met; therefore, initiatives that focus on patient-centered care that promote long-term self-management for chronic conditions should be at the forefront of service redesign. The use of innovative technologies and the ability to apply these effectively to promote behavior change are paramount in meeting the current challenges. Objective: Our objective was to gain a deeper insight into the impact of innovative technologies in support of home-based, self-managed rehabilitation for stroke survivors. An intervention of daily walks can assist with improving lower limb motor function, and this can be measured by using technology. This paper focuses on assessing the usage of self-management technologies on poststroke survivors while undergoing rehabilitation at home. Methods: A realist evaluation of a personalized self-management rehabilitation system was undertaken in the homes of stroke survivors (N=5) over a period of approximately two months. Context, mechanisms, and outcomes were developed and explored using theories relating to motor recovery. Participants were encouraged to self-manage their daily walking activity; this was achieved through goal setting and motivational feedback. Gait data were collected and analyzed to produce metrics such as speed, heel strikes, and symmetry. This was achieved using a “smart insole” to facilitate measurement of walking activities in a free-living, nonrestrictive environment. Results: Initial findings indicated that 4 out of 5 participants performed better during the second half of the evaluation. Performance increase was evident through improved heel strikes on participants’ affected limb. Additionally, increase in performance in relation to speed was also evident for all 5 participants. A common strategy emerged across all but one participant as symmetry performance was sacrificed in favor of improved heel strikes. This paper evaluates compliance and intensity of use. Conclusion: Our findings suggested that 4 out of the 5 participants improved their ability to heel strike on their affected limb. All participants showed improvements in their speed of gait measured in steps per minute with an average increase of 9.8% during the rehabilitation program. Performance in relation to symmetry showed an 8.5% average decline across participants, although 1 participant improved by 4%. Context, mechanism, and outcomes indicated that dual motor learning and compensatory strategies were deployed by the participants

    Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage

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    We report a novel technology for the rapid healing of large osseous and chondral defects, based upon the genetic modification of autologous skeletal muscle and fat grafts. These tissues were selected because they not only possess mesenchymal progenitor cells and scaffolding properties, but also can be biopsied, genetically modified and returned to the patient in a single operative session. First generation adenovirus vector carrying cDNA encoding human bone morphogenetic protein-2 (Ad.BMP-2) was used for gene transfer to biopsies of muscle and fat. To assess bone healing, the genetically modified ("gene activated") tissues were implanted into 5mm-long critical size, mid-diaphyseal, stabilized defects in the femora of Fischer rats. Unlike control defects, those receiving gene-activated muscle underwent rapid healing, with evidence of radiologic bridging as early as 10 days after implantation and restoration of full mechanical strength by 8 weeks. Histologic analysis suggests that the grafts rapidly differentiated into cartilage, followed by efficient endochondral ossification. Fluorescence in situ hybridization detection of Y-chromosomes following the transfer of male donor muscle into female rats demonstrated that at least some of the osteoblasts of the healed bone were derived from donor muscle. Gene activated fat also healed critical sized defects, but less quickly than muscle and with more variability. Anti-adenovirus antibodies were not detected. Pilot studies in a rabbit osteochondral defect model demonstrated the promise of this technology for healing cartilage defects. Further development of these methods should provide ways to heal bone and cartilage more expeditiously, and at lower cost, than is presently possible

    Northeastern united states species treated with copper-based preservatives: Durability in mississippi stake tests

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    This paper reports on the ground-contact durability of lesser-used wood species of the northeastern United States after treatment with copper-based preservatives. Stakes (19 by 19 by 457 mm) cut from balsam-fir (Abies balsamea), eastern hemlock (Tsuga canadensis), eastern spruce (mixture of Picea glauca, Picea mariana and Picea rubens), red maple (Acer rubrum) or eastern white pine (Pinus strobus) were treated with one of four concentrations of chromated copper arsenate type C (CCA-C), copper citrate (CC), alkaline copper quat type C (ACQ-C) or copper azole type A (CBA-A) and placed into the ground at a test site in southern Mississippi. Similarly treated southern pine (Pinus spp.) stakes were included for comparison. The stakes were rated for decay and termite attack after 1, 2, 3, 4, 5, 8, 10 and 12 years. Eastern white pine and incised eastern hemlock and balsam-fir had durability similar to southern pine when treated with CCA or the other copper-based preservatives. Eastern spruce was less durable than the other softwood species, apparently because of low preservative uptake. Red maple had the least durability at all retentions and for all preservatives. This study indicates that several northeastern softwoods can be adequately durable when pressure-treated with CCA-C or copper-based preservatives

    Platelet rich plasma injection grafts for musculoskeletal injuries: a review

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    In Europe and the United States, there is an increasing prevalence of the use of autologous blood products to facilitate healing in a variety of applications. Recently, we have learned more about specific growth factors, which play a crucial role in the healing process. With that knowledge there is abundant enthusiasm in the application of concentrated platelets, which release a supra-maximal quantity of these growth factors to stimulate recovery in non-healing injuries. For 20 years, the application of autologous PRP has been safely used and documented in many fields including; orthopedics, sports medicine, dentistry, ENT, neurosurgery, ophthalmology, urology, wound healing, cosmetic, cardiothoracic, and maxillofacial surgery. This article introduces the reader to PRP therapy and reviews the current literature on this emerging treatment modality. In summary, PRP provides a promising alternative to surgery by promoting safe and natural healing. However, there are few controlled trials, and mostly anecdotal or case reports. Additionally the sample sizes are frequently small, limiting the generalization of the findings. Recently, there is emerging literature on the beneficial effects of PRP for chronic non-healing tendon injuries including lateral epicondylitis and plantar fasciitis and cartilage degeneration (Mishra and Pavelko, The American Journal of Sports Medicine 10(10):1–5, 2006; Barrett and Erredge, Podiatry Today 17:37–42, 2004). However, as clinical use increases, more controlled studies are needed to further understand this treatment

    Exploring Aboriginal People\u27s connection to country to strengthen human-nature theoretical perspectives

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    Purpose Aboriginal people across Australia have diverse practices, beliefs and knowledges based on thousands of generations of managing and protecting their lands (Country). The intimate relationship Aboriginal people have with their Country is explored in this chapter because such knowledge is important for building insight into the relationship between social and ecological systems. Often in research Aboriginal views have been marginalised from discussions focused on their lands to the detriment of ecosystems and human health. This chapter aims to understand if such marginalisation is evident in Western human–nature relationship discourses.Approach This chapter provides a critical literature review which examines whether Aboriginal people’s diverse understanding of their ecosystems have been incorporated into human–nature theories using the biophilia hypothesis as a starting point. Other concepts explored include solastalgia, topophilia and place.Findings Critiques of these terminologies in the context of Aboriginal people’s connection to Country are limited but such incorporation is viewed in the chapter as a possible mechanism for better understanding human’s connection to nature. The review identified that Aboriginal people’s relationship to Country seems to be underrepresented in the human–nature theory literature.Value This chapter emphasises that the integration of Aboriginal perspectives into research, ecological management and policy can provide better insight into the interrelationships between social and ecological systems

    Actinide covalency measured by pulsed electron paramagnetic resonance spectroscopy

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    Our knowledge of actinide chemical bonds lags far behind our understanding of the bonding regimes of any other series of elements. This is a major issue given the technological as well as fundamental importance of f-block elements. Some key chemical differences between actinides and lanthanides—and between different actinides—can be ascribed to minor differences in covalency, that is, the degree to which electrons are shared between the f-block element and coordinated ligands. Yet there are almost no direct measures of such covalency for actinides. Here we report the first pulsed electron paramagnetic resonance spectra of actinide compounds. We apply the hyperfine sublevel correlation technique to quantify the electron-spin density at ligand nuclei (via the weak hyperfine interactions) in molecular thorium(III) and uranium(III) species and therefore the extent of covalency. Such information will be important in developing our understanding of the chemical bonding, and therefore the reactivity, of actinides
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