314 research outputs found
Quantum Equivalence of Massive Antisymmetric Tensor Field Models in Curved Space
We study the effective actions for massive rank-2 and rank-3 antisymmetric
tensor field models in curved space-time. These models are classically
equivalent to massive vector field and massive scalar field with minimal
coupling to gravity respectively. We prove that effective action for massive
rank-2 antisymmetric tensor field is exactly equal to one for massive vector
field and effective action for massive rank-3 antisymmetric tensor field is
exactly equal to one for massive scalar field. Prove is based on an identity
for mass-dependent zeta-functions associated with Laplacians acting on
-forms.Comment: 8 pages, REVTeX fil
Base of scientific and biomedical data the object formation of competencies in the discipline of biochemistry of Medical schools
The article describes the algorithm of formation of cultural and professional competences of students in medical University during research work with the use of web services created based on biomedical databasesВ статье описывается алгоритм формирования общекультурных, общепрофессиональных и профессиональных компетенций у обучающихся в медицинском вузе при проведении научно-исследовательской работы (НИР) с применением веб-сервисов, созданных на основе биомедицинских баз данны
The action of bacillus' metzinc metalloproteinase on cultured animal cell lines
Microbial enzymes with high activity are increasingly used in medical practice in development of drugs for treatment of burn injuries, diseases of gastrointestinal tract, as well as in systemic enzyme therapy. One of crucial requirements for such drugs is the absence of toxicity, both on cellular and organism levels. The aim of the present study was to evaluate cytotoxic effect of Bacillus pumilus metzinc metalloproteinase on animal cell lines. Cytological changes in LEK, Vero and PK-15 cell lines were observed after cell treatment with 155 μ/ml enzyme. However, lower enzyme concentrations - 75 and 15 μ/ml did not show any toxicity
WebFR3D—a server for finding, aligning and analyzing recurrent RNA 3D motifs
WebFR3D is the on-line version of ‘Find RNA 3D’ (FR3D), a program for annotating atomic-resolution RNA 3D structure files and searching them efficiently to locate and compare RNA 3D structural motifs. WebFR3D provides on-line access to the central features of FR3D, including geometric and symbolic search modes, without need for installing programs or downloading and maintaining 3D structure data locally. In geometric search mode, WebFR3D finds all motifs similar to a user-specified query structure. In symbolic search mode, WebFR3D finds all sets of nucleotides making user-specified interactions. In both modes, users can specify sequence, sequence–continuity, base pairing, base-stacking and other constraints on nucleotides and their interactions. WebFR3D can be used to locate hairpin, internal or junction loops, list all base pairs or other interactions, or find instances of recurrent RNA 3D motifs (such as sarcin–ricin and kink-turn internal loops or T- and GNRA hairpin loops) in any PDB file or across a whole set of 3D structure files. The output page provides facilities for comparing the instances returned by the search by superposition of the 3D structures and the alignment of their sequences annotated with pairwise interactions. WebFR3D is available at http://rna.bgsu.edu/webfr3d
The soft and the hard pomerons in hadron elastic scattering at small t
We consider simple-pole descriptions of soft elastic scattering for pp, pbar
p, pi+ p, pi- p, K+ p and K- p. We work at t and s small enough for
rescatterings to be neglected, and allow for the presence of a hard pomeron.
After building and discussing an exhaustive dataset, we show that simple poles
provide an excellent description of the data in the region - 0.5 GeV^2 < t <
-0.1 GeV^2, 6 GeV<sqrt(s)< 63 GeV. We show that new form factors have to be
used, and get information on the trajectories of the soft and hard pomerons.Comment: 27 pages, 9 figures, LaTeX. A few typos fixed, and references
correcte
Live Birth of a Healthy Child in a Couple with Identical mtDNA Carrying a Pathogenic c.471_477delTTTAAAAinsG Variant in the MOCS2 Gene.
Molybdenum cofactor deficiency type B (MOCODB; #252160) is an autosomal recessive metabolic disorder that has only been described in 37 affected patients. In this report, we describe the presence of an in-frame homozygous variant (c.471_477delTTTAAAAinsG) in the MOCS2 gene in an affected child, diagnosed with Ohtahara syndrome according to the clinical manifestations. The analysis of the three-dimensional structure of the protein and the amino acid substitutions suggested the pathogenicity of this mutation. To prevent transmitting this mutation to the next generation, we used preimplantation genetic testing for the monogenic disorders (PGT-M) protocol to select MOCS2 gene mutant-free embryos for transfer in an in vitro fertilization (IVF) program. As a result, a healthy child was born. Interestingly, both parents of the proband shared an identical mitochondrial (mt) DNA control region, assuming their close relationship and thus suggesting that both copies of the nuclear rare variant c.471_477delTTTAAAAinsG may have been transmitted from the same female ancestor. Our estimation of the a priori probability of meeting individuals with the same mtDNA haplotype confirms the assumption of a possible distant maternal relationship among the proband's direct relatives
Introduction to half-metallic Heusler alloys: Electronic Structure and Magnetic Properties
Intermetallic Heusler alloys are amongst the most attractive half-metallic
systems due to the high Curie temperatures and the structural similarity to the
binary semiconductors. In this review we present an overview of the basic
electronic and magnetic properties of both Heusler families: the so-called
half-Heusler alloys like NiMnSb and the the full-Heusler alloys like
CoMnGe. \textit{Ab-initio} results suggest that both the electronic and
magnetic properties in these compounds are intrinsically related to the
appearance of the minority-spin gap. The total spin magnetic moment
scales linearly with the number of the valence electrons , such that
for the full-Heusler and for the half-Heusler alloys,
thus opening the way to engineer new half-metallic alloys with the desired
magnetic properties.Comment: 28 pages, submitted for a special issue of 'Journal of Physics D:
Applied Physics' on Heusler alloy
L.L. Fofanof: 140th anniversary of his birth. Contribution to science
The article is dedicated to Professor L.L. Fofanof’s scientific activity. He headed the faculty therapeutic clinic of Kazan Imperial University in 1915-1920. Being a student L.L. Fofanov was interested in pathological anatomy and physiology. His dissertation «To physiology of n. depressoris» was dedicated to studying the vasomotor center. During his visit in Germany he worked a lot. In Charite together with Professor His he studied gout and its treatment with Radium emanation. In Halle clinic under Professor Schmidt’s supervision he studied assimilation of starch in normal and pathological digestion. L.L. Fofanov also made a contribution to tuberculosis treatment: with professor V.F. Orlovskiy he studied treatment of tuberculosis with simulated pneumothorax. In his research professor L.L. Fofanov paid great attention to the issues of pathogenesis and pathogenetic substantiation of the clinical manifestation and treatment. During the World War I and Civil War he fought against typhus epidemies: he saw patients, gave lectures, studied the features of myocardial involvement. He died in 1920 from typhus
PHASE COMPOSITION OF THE Co–10Al–9W ALLOY
В работе приведены результаты теоретического расчета фазовой диаграммы тройной системы Co–Al–W с использованием программного обеспечения Thermo-Calc Software, а также металлографических и рентгеновских исследований образцов сплава Co–10Al–9W после различных режимов обработки.The calculation phase diagram of the Co–Al–W system was carried out by the Thermo-Calc Software. Metallographic and X-ray investigations of the Co– 10Al–9W alloy simples after different thermomechanical treatments are performed
Road map for the development of competences in scientific research-based biomedical databases
The article describes the algorithm of formation of cultural and professional competences of students in medical University during research work with the use of web services created based on biomedical databases. Formation of competences corresponds to the provisions of the Federal state educational standard of higher education in the field of training 31.05.01 (ОК-1, ОК-5, ОПК-1, ОПК-5, ОПК-7, ПК-4, ПК-20, ПК-21, ПК-22).В статье описывается алгоритм формирования общекультурных, общепрофессиональных и профессиональных компетенций у обучающихся в медицинском Вузе при проведении научно-исследовательской работы (НИР) с применением веб-сервисов, созданных на основе биомедицинских баз данных. Формирование компетенций соответствует положениям федерального государственного образовательного стандарта высшего образования по направлению подготовки 31.05.01 Лечебное дело (ОК1, ОК-5, ОПК-1, ОПК-5, ОПК-7, ПК-4, ПК-20, ПК-21, ПК-22
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