Numerical study of large-eddy breakup and its effect on the drag characteristics of boundary layers

The break-up of a field of eddies by a flat-plate obstacle embedded in a boundary layer is studied using numerical solutions to the two-dimensional Navier-Stokes equations. The flow is taken to be incompressible and unsteady. The flow field is initiated from rest. A train of eddies of predetermined size and strength are swept into the computational domain upstream of the plate. The undisturbed velocity profile is given by the Blasius solution. The disturbance vorticity generated at the plate and wall, plus that introduced with the eddies, mix with the background vorticity and is transported throughout the entire flow. All quantities are scaled by the plate length, the unidsturbed free-stream velocity, and the fluid kinematic viscosity. The Reynolds number is 1000, the Blasius boundary layer thickness is 2.0, and the plate is positioned a distance of 1.0 above the wall. The computational domain is four units high and sixteen units long

A Nonclassical Dihydrogen Adduct of S = ½ Fe(I)

We have exploited the capacity of the “(SiP^(iPr)_3)Fe(I)” scaffold to accommodate additional axial ligands and characterized the mononuclear S = 1/2 H_2 adduct complex (SiP^(iPr)_3)Fe^I(H_2). EPR and ENDOR data, in the context of X-ray structural results, revealed that this complex provides a highly unusual example of an open-shell metal complex that binds dihydrogen as a ligand. The H2 ligand at 2 K dynamically reorients within the ligand-binding pocket, tunneling among the energy minima created by strong interactions with the three Fe–P bonds

Starbursts and Star Clusters in the Ultraviolet

Hubble Space Telescope ultraviolet (UV) images of nine starburst galaxies reveal them to be highly irregular, even after excluding compact sources (clusters and resolved stars). Most (7/9) are found to have a similar intrinsic effective surface brightnesses, suggesting that a negative feedback mechanism is setting an upper limit to the star formation rate per unit area. All starbursts in our sample contain UV bright star clusters indicating that cluster formation is an important mode of star formation in starbursts. On average about 20% of the UV luminosity comes from these clusters. The brightest clusters, or super star clusters (SSC), are preferentially found at the very heart of starbursts. The size of the nearest SSCs are consistent with those of Galactic globular clusters. The luminosity function of SSCs is well represented by a power law with a slope alpha ~ -2. There is a strong correlation between the far infrared excess and the UV spectral slope. The correlation is well modeled by a geometry where much of their dust is in a foreground screen near to the starburst, but not by a geometry of well mixed stars and dust.Comment: 47 pages, text only, LaTeX with aaspp.sty (version 3.0), compressed postscript figures available at ftp://eta.pha.jhu.edu/RecentPublications/meurer

Analytical procedure results as substantive evidence

https://egrove.olemiss.edu/dl_proceedings/1085/thumbnail.jp

Jet directions in Seyfert galaxies: B and I imaging data

We present the results of broad-band B and I imaging observations for a sample of 88 Seyfert galaxies (29 Seyfert 1's and 59 Seyfert 2's), selected from a mostly isotropic property, the flux at 60$\mu$m. We also present the B and I imaging results for an additional sample of 20 Seyfert galaxies (7 Seyfert 1's and 13 Seyfert 2's), selected from the literature and known to have extended radio emission. The I band images are fitted with ellipses to determine the position angle and ellipticity of the host galaxy major axis. This information will be used in a future paper, combined with information from radio observations, to study the orientation of radio jets relative to the plane of their host galaxies (Kinney et al. 2000). Here we present surface brightness profiles and magnitudes in the B and I bands, as well as mean ellipticities and major axis position angles.Comment: To appear in The Astrophysical Journal Supplement Series, June 2000. 48 pages, 7 tables, 19 gif and 11 postscript figures. Better quality figures can be obtained with the autho

Leadership of the Consortium for Health Policy, Law and Bioethics

poster abstractThe Consortium for Health Policy, Law, and Bioethics completed another successful year of educational programs, public outreach, and collaborative research. Educational highlights include (1) offering for the second time, an innovative graduate course co-taught by the three Consortium-directors (Wright, Kinney, Meslin) that is open to students in law, public health, philosophy; (2) The addition of a new “concentration in international research ethics” (offered in the Philosophy Department that is now eligible for joint-degree status with the JD; and (3) approval of a new JD/MSW. Research highlights include (1) twenty publications (2) several grants awarded to Consortium co-directors; $4,958,909.75 and (3) the establishment of year-long a multidisciplinary study group focusing on ethical, legal, social, and policy issues involving comparative effectiveness research. Outreach highlights include nine presentations to community groups, professional associations, and academic institutions

Recruitment of Dental Hygiene Students from Underrepresented Minority Groups: A National Survey of U.S. Dental Hygiene Programs

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153698/1/jddj0022033720157910tb06010x.pd

Numerical solutions of the three-dimensional magnetohydrodynamic alpha-model

We present direct numerical simulations and alpha-model simulations of four familiar three-dimensional magnetohydrodynamic (MHD) turbulence effects: selective decay, dynamic alignment, inverse cascade of magnetic helicity, and the helical dynamo effect. The MHD alpha-model is shown to capture the long-wavelength spectra in all these problems, allowing for a significant reduction of computer time and memory at the same kinetic and magnetic Reynolds numbers. In the helical dynamo, not only does the alpha-model correctly reproduce the growth rate of magnetic energy during the kinematic regime, but it also captures the nonlinear saturation level and the late generation of a large scale magnetic field by the helical turbulence.Comment: 12 pages, 19 figure

Measuring the sequence-affinity landscape of antibodies with massively parallel titration curves

Despite the central role that antibodies play in the adaptive immune system and in biotechnology, much remains unknown about the quantitative relationship between an antibody's amino acid sequence and its antigen binding affinity. Here we describe a new experimental approach, called Tite-Seq, that is capable of measuring binding titration curves and corresponding affinities for thousands of variant antibodies in parallel. The measurement of titration curves eliminates the confounding effects of antibody expression and stability that arise in standard deep mutational scanning assays. We demonstrate Tite-Seq on the CDR1H and CDR3H regions of a well-studied scFv antibody. Our data shed light on the structural basis for antigen binding affinity and suggests a role for secondary CDR loops in establishing antibody stability. Tite-Seq fills a large gap in the ability to measure critical aspects of the adaptive immune system, and can be readily used for studying sequence-affinity landscapes in other protein systems

New Solutions of the Inflationary Flow Equations

The inflationary flow equations are a frequently used method of surveying the space of inflationary models. In these applications the infinite hierarchy of differential equations is truncated in a way which has been shown to be equivalent to restricting the set of models considered to those characterized by polynomial inflaton potentials. This paper explores a different method of solving the flow equations, which does not truncate the hierarchy and in consequence covers a much wider class of models while retaining the practical usability of the standard approach.Comment: References added, and a couple of comment