A Firm Upper Limit to the Radius of the Neutron Star in SAX J1808.4-3658

We show that observations of X-ray pulsing from SAX J1808.4-3658 place a firm upper limit of 13.8 m^{1/3} km on the radius of the neutron star, where m is its mass in solar units. The limit is independent of distance or assumptions about the magnetospheric geometry, and could be significantly tightened by observations of the pulsations in the near future. We discuss the implications for the equation of state and the possible neutron star mass.Comment: (7 pages, 1 figure, accepted for publication in ApJ Letters

Nonuniqueness in a minimal model for cell motility

Two–phase flow models have been used previously to model cell motility, however these have rapidly become very complicated, including many physical processes, and are opaque. Here we demonstrate that even the simplest one–dimensional, two–phase, poroviscous, reactive flow model displays a number of behaviours relevant to cell crawling. We present stability analyses that show that an asymmetric perturbation is required to cause a spatially uniform, stationary strip of cytoplasm to move, which is relevant to cell polarization. Our numerical simulations identify qualitatively distinct families of travelling–wave solution that co–exist at certain parameter values. Within each family, the crawling speed of the strip has a bell–shaped dependence on the adhesion strength. The model captures the experimentally observed behaviour that cells crawl quickest at intermediate adhesion strengths, when the substrate is neither too sticky nor too slippy

The AGN-starburst connection, Galactic superwinds, and M_BH - sigma

Recent observations of young galaxies at redshifts z ~ 3 have revealed simultaneous AGN and starburst activity, as well as galaxy-wide superwinds. I show that there is probably a close connection between these phenomena by extending an earlier treatment of the M_BH - sigma relation (King, 2003). As the black hole grows, an outflow drives a shell into the surrounding gas. This stalls after a dynamical time at a size determined by the hole's current mass and thereafter grows on the Salpeter timescale. The gas trapped inside this bubble cools and forms stars and is recycled as accretion and outflow. The consequent high metallicity agrees with that commonly observed in AGN accretion. Once the hole reaches a critical mass this region attains a size such that the gas can no longer cool efficiently. The resulting energy-driven flow expels the remaining gas as a superwind, fixing both the M_BH - sigma relation and the total stellar bulge mass at values in good agreement with observation. Black hole growth thus produces starbursts and ultimately a superwind.Comment: ApJ, in press, 4 page

Li I and K I Scatter in Cool Pleiades Dwarfs

We utilize high-resolution (R~60,000), high S/N (~100) spectroscopy of 17 cool Pleiades dwarfs to examine the confounding star-to-star scatter in the 6707 Li I line strengths in this young cluster. Our Pleiads, selected for their small projected rotational velocity and modest chromospheric emission, evince substantial scatter in the linestrengths of 6707 Li I feature that is absent in the 7699 K I resonance line. The Li I scatter is not correlated with that in the high-excitation 7774 O I feature, and the magnitude of the former is greater than the latter despite the larger temperature sensitivity of the O I feature. These results suggest that systematic errors in linestrength measurements due to blending, color (or color-based T_eff) errors, or line formation effects related to an overlying chromosphere are not the principal source of Li I scatter in our stars. There do exist analytic spot models that can produce the observed Li scatter without introducing scatter in the K I line strengths or the color-magnitude diagram. However, these models predict factor of >3 differences in abundances derived from the subordinate 6104 and resonance 6707 Li I features; we find no difference in the abundances determined from these two features. These analytic spot models also predict CN line strengths significantly larger than we observe in our spectra. The simplest explanation of the Li, K, CN, and photometric data is that there must be a real abundance component to the Pleiades Li dispersion. We suggest that this real abundance component is the manifestation of relic differences in erstwhile pre-main-sequence Li burning caused by effects of surface activity on stellar structure. We discuss observational predictions of these effects.Comment: 35 pages, 7 figures; accepted by Ap

An interplanetary magnetic field ensemble at 1 AU

A method for calculation ensemble averages from magnetic field data is described. A data set comprising approximately 16 months of nearly continuous ISEE-3 magnetic field data is used in this study. Individual subintervals of this data, ranging from 15 hours to 15.6 days comprise the ensemble. The sole condition for including each subinterval in the averages is the degree to which it represents a weakly time-stationary process. Averages obtained by this method are appropriate for a turbulence description of the interplanetary medium. The ensemble average correlation length obtained from all subintervals is found to be 4.9 x 10 to the 11th cm. The average value of the variances of the magnetic field components are in the approximate ratio 8:9:10, where the third component is the local mean field direction. The correlation lengths and variances are found to have a systematic variation with subinterval duration, reflecting the important role of low-frequency fluctuations in the interplanetary medium

A national register for surveillance of inherited disorders: beta thalassaemia in the United Kingdom

OBJECTIVE: To demonstrate the value of a national register for surveillance of services for an inherited disorder. METHODS: Data from the United Kingdom Thalassaemia Register and the United Kingdom Register of Prenatal Diagnosis for Haemoglobin Disorders were combined in a database; these registers include all fetuses known to have been diagnosed with beta thalassaemia major, beta thalassaemia intermedia, or haemoglobin E/beta thalassaemia in the United Kingdom. Data were extracted to show outcomes (selective abortion or live birth) of all fetuses and the status of those born with a disorder (alive, dead, successful bone marrow transplant, or lost to follow-up) by parents' region of residence and ethnicity. FINDINGS: At the end of 1999 the register included 1074 patients, 807 of whom were alive and residing in the United Kingdom. A successful bone marrow transplant has been performed for 117 out of 581 (20%) patients born since 1975. Residents of Pakistani origin are now the main group at risk in the United Kingdom, replacing residents of Cypriot origin. This has led to a marked shift in the need for services from the south-east of England to the Midlands and the north of England. Despite the acceptability of prenatal diagnosis, the proportion of affected births remains 50% higher than would be expected, reflecting a widespread failure to deliver timely screening and counselling to carriers. Even though effective treatment is available the annual number of deaths is rising, indicating that better tolerated treatments are needed. CONCLUSION: A national diagnosis register is a powerful instrument for monitoring the treatment and prevention of inherited disorders and for highlighting correctable shortcomings. In view of the increasing possibilities for genetic screening there is a strong case for central funding for such databases within modern health services

Atmospheric nitrogen oxides (NO and NO2) at Dome C, East Antarctica, during the OPALE campaign

Mixing ratios of the atmospheric nitrogen oxides NO and NO2 were measured as part of the OPALE (Oxidant Production in Antarctic Lands & Export) campaign at Dome C, East Antarctica (75.1 degrees S, 123.3 degrees E, 3233 m), during December 2011 to January 2012. Profiles of NOx mixing ratios of the lower 100m of the atmosphere confirm that, in contrast to the South Pole, air chemistry at Dome C is strongly influenced by large diurnal cycles in solar irradiance and a sudden collapse of the atmospheric boundary layer in the early evening. Depth profiles of mixing ratios in firn air suggest that the upper snowpack at Dome C holds a significant reservoir of photolytically produced NO2 and is a sink of gas-phase ozone (O-3). First-time observations of bromine oxide (BrO) at Dome C show that mixing ratios of BrO near the ground are low, certainly less than 5 pptv, with higher levels in the free troposphere. Assuming steady state, observed mixing ratios of BrO and RO2 radicals are too low to explain the large NO2 : NO ratios found in ambient air, possibly indicating the existence of an unknown process contributing to the atmospheric chemistry of reactive nitrogen above the Antarctic Plateau. During 2011-2012, NOx mixing ratios and flux were larger than in 2009-2010, consistent with also larger surface O-3 mixing ratios resulting from increased net O-3 production. Large NOx mixing ratios at Dome C arise from a combination of continuous sunlight, shallow mixing height and significant NOx emissions by surface snow (F-NOx). During 23 December 2011-12 January 2012, median F-NOx was twice that during the same period in 20092010 due to significantly larger atmospheric turbulence and a slightly stronger snowpack source. A tripling of F-NOx in December 2011 was largely due to changes in snowpack source strength caused primarily by changes in NO3- concentrations in the snow skin layer, and only to a secondary order by decrease of total column O-3 and associated increase in NO3- photolysis rates. A source of uncertainty in model estimates of F-NOx is the quantum yield of NO3- photolysis in natural snow, which may change over time as the snow ages