37 research outputs found

    RsrI: A new sequence-specific endonuclease from rhodopseudomonas spaeroides

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    Thesis (B.S.) in Liberal Arts and Sciences--University of Illinois at Urbana-Champaign, 1984.Bibliography: leaves 11-12.U of I OnlyTheses restricted to UIUC community onl

    Delayed administration of the anti-RAGE antibody is protective in cecal ligation and puncture (CLP)

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    <p><b>Copyright information:</b></p><p>Taken from "Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection"</p><p>http://ccforum.com/content/11/6/R122</p><p>Critical Care 2007;11(6):R122-R122.</p><p>Published online 6 Nov 2007</p><p>PMCID:PMC2246216.</p><p></p> The Kaplan-Meier survival analysis following CLP in BALB/c mice compares delayed anti-RAGE monoclonal antibody (mAb) treatment given at various time intervals after CLP with serum control. Each group had a significantly greater survival than the control group (< 0.01), except for the 36-hour delayed treatment group (= 0.12). RAGE, receptor for advanced glycation end products

    Modulation of receptor for advanced glycation end products (RAGE) protects mice from the effects of cecal ligation and puncture (CLP)

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    <p><b>Copyright information:</b></p><p>Taken from "Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection"</p><p>http://ccforum.com/content/11/6/R122</p><p>Critical Care 2007;11(6):R122-R122.</p><p>Published online 6 Nov 2007</p><p>PMCID:PMC2246216.</p><p></p> Kaplan-Meier survival analysis following CLP comparing wild-type RAGE129SvEvBrd mice (= 15), RAGEmice (= 15), RAGEmice (= 23), and anti-RAGE monoclonal antibody-treated (15 mg/kg intravenously 30 to 60 minutes before CLP) wild-type mice (= 15). < 0.001 for each group in comparison with the wild-type CLP control group. Sham surgery-treated wild-type 129SvEvBrd mice (= 5) were used as an additional control group. WT, wild-type
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