The Lantern Vol. 47, No. 1, December 1980

• Renewal • She Threw Down Her Diamond • Ragnarok • Cinquains • Euphoria • To the Nahua of the Valley of Mexico • Inamorata • Unspoken Passion • Clouds of Circus Cotton Candy Pink • The First Mate Finds a Captain (Almost) • Dance of Defiance • Concert • Blame • I\u27ve Seen That Movie Too • Greystone • The Philosophers of The Tower • Span • Commando • Cheshire • Summertime, Kryptonite and Falstaf(f) • Experience • Fluid Time • The Plight of Fred in Bed • A Way With Men • Courage to Love - (To A.) • Winter Sleep • Berniehttps://digitalcommons.ursinus.edu/lantern/1117/thumbnail.jp

The Lantern Vol. 47, No. 1, December 1980

• Renewal • She Threw Down Her Diamond • Ragnarok • Cinquains • Euphoria • To the Nahua of the Valley of Mexico • Inamorata • Unspoken Passion • Clouds of Circus Cotton Candy Pink • The First Mate Finds a Captain (Almost) • Dance of Defiance • Concert • Blame • I\u27ve Seen That Movie Too • Greystone • The Philosophers of The Tower • Span • Commando • Cheshire • Summertime, Kryptonite and Falstaf(f) • Experience • Fluid Time • The Plight of Fred in Bed • A Way With Men • Courage to Love - (To A.) • Winter Sleep • Berniehttps://digitalcommons.ursinus.edu/lantern/1117/thumbnail.jp

Contaminated Turmeric Is a Potential Source of Lead Exposure for Children in Rural Bangladesh

Background. During the conduct of a cohort study intended to study the associations between mixed metal exposures and child health outcomes, we found that 78% of 309 children aged 20–40 months evaluated in the Munshiganj District of Bangladesh had blood lead concentrations ≥5 µg/dL and 27% had concentrations ≥10 µg/dL. Hypothesis. Environmental sources such as spices (e.g., turmeric, which has already faced recalls in Bangladesh due to high lead levels) may be a potential route of lead exposure. Methods. We conducted visits to the homes of 28 children randomly selected from among high and low blood lead concentration groups. During the visits, we administered a structured questionnaire and obtained soil, dust, rice, and spice samples. We obtained water samples from community water sources, as well as environmental samples from neighborhood businesses. Results. Lead concentrations in many turmeric samples were elevated, with lead concentrations as high as 483 ppm. Analyses showed high bioaccessibility of lead. Conclusions. Contamination of turmeric powder is a potentially important source of lead exposure in this population

Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans

The formation of mammalian dendritic cells (DCs) is controlled by multiple hematopoietic transcription factors, including IRF8. Loss of IRF8 exerts a differential effect on DC subsets, including plasmacytoid DCs (pDCs) and the classical DC lineages cDC1 and cDC2. In humans, cDC2-related subsets have been described including AXL+ SIGLEC6+ pre-DC, DC2 and DC3. The origin of this heterogeneity is unknown. Using highdimensional analysis, in vitro differentiation, and an allelic series of human IRF8 deficiency, we demonstrated that cDC2 (CD1c+ DC) heterogeneity originates from two distinct pathways of development. The lymphoidprimed IRF8hi pathway, marked by CD123 and BTLA, carried pDC, cDC1, and DC2 trajectories, while the common myeloid IRF8lo pathway, expressing SIRPA, formed DC3s and monocytes. We traced distinct trajectories through the granulocyte-macrophage progenitor (GMP) compartment showing that AXL+ SIGLEC6+ pre-DCs mapped exclusively to the DC2 pathway. In keeping with their lower requirement for IRF8, DC3s expand to replace DC2s in human partial IRF8 deficiency

Search for heavy lepton resonances decaying to a ZZ boson and a lepton in pppp collisions at s=8\sqrt{s}=8 TeV with the ATLAS detector

A search for heavy leptons decaying to a $Z$ boson and an electron or a muon is presented. The search is based on $pp$ collision data taken at $\sqrt{s}=8$ TeV by the ATLAS experiment at the CERN Large Hadron Collider, corresponding to an integrated luminosity of 20.3 fb$^{-1}$, Three high-transverse-momentum electrons or muons are selected, with two of them required to be consistent with originating from a $Z$ boson decay. No significant excess above Standard Model background predictions is observed, and 95% confidence level limits on the production cross section of high-mass trilepton resonances are derived. The results are interpreted in the context of vector-like lepton and type-III seesaw models. For the vector-like lepton model, most heavy lepton mass values in the range 114-176 GeV are excluded. For the type-III seesaw model, most mass values in the range 100-468 GeV are excluded

Measurement of distributions sensitive to the underlying event in inclusive Z-boson production in pp collisions at √s = 7 TeV with the ATLAS detector

A measurement of charged-particle distributions sensitive to the properties of the underlying event is presented for an inclusive sample of events containing a TeX -boson, decaying to an electron or muon pair. The measurement is based on data collected using the ATLAS detector at the LHC in proton–proton collisions at a centre-of-mass energy of TeX TeV with an integrated luminosity of TeX fb TeX . Distributions of the charged particle multiplicity and of the charged particle transverse momentum are measured in regions of azimuthal angle defined with respect to the TeX -boson direction. The measured distributions are compared to similar distributions measured in jet events, and to the predictions of various Monte Carlo generators implementing different underlying event models

Measurement of the muon reconstruction performance of the ATLAS detector using 2011 and 2012 LHC proton–proton collision data

This paper presents the performance of the ATLAS muon reconstruction during the LHC run with pp collisions at √s = 7–8 TeV in 2011–2012, focusing mainly on data collected in 2012. Measurements of the reconstruction efficiency and of the momentum scale and resolution, based on large reference samples of J/ψ → μμ, Z → μμ and ϒ → μμ decays, are presented and compared to Monte Carlo simulations. Corrections to the simulation, to be used in physics analysis, are provided. Over most of the covered phase space (muon |η| < 2.7 and 5 ≲pT ≲pT 100 GeV) the efficiency is above 99% and is measured with per-mille precision. The momentum resolution ranges from 1.7% at central rapidity and for transverse momentum pT ≃ 10 GeV, to 4% at large rapidity and pT ≃ 100 GeV. The momentum scale is known with an uncertainty of 0.05% to 0.2% depending on rapidity. A method for the recovery of final state radiation from the muons is also presented

Yolk sac cell atlas reveals multiorgan functions during human early development

The extraembryonic yolk sac (YS) ensures delivery of nutritional support and oxygen to the developing embryo but remains ill-defined in humans. We therefore assembled a comprehensive multiomic reference of the human YS from 3 to 8 postconception weeks by integrating single-cell protein and gene expression data. Beyond its recognized role as a site of hematopoiesis, we highlight roles in metabolism, coagulation, vascular development, and hematopoietic regulation. We reconstructed the emergence and decline of YS hematopoietic stem and progenitor cells from hemogenic endothelium and revealed a YS-specific accelerated route to macrophage production that seeds developing organs. The multiorgan functions of the YS are superseded as intraembryonic organs develop, effecting a multifaceted relay of vital functions as pregnancy proceeds

Search for new phenomena in events containing a same-flavour opposite-sign dilepton pair, jets, and large missing transverse momentum in s=\sqrt{s}= 13 pppp collisions with the ATLAS detector

Two searches for new phenomena in final states containing a same-flavour opposite-lepton (electron or muon) pair, jets, and large missing transverse momentum are presented. These searches make use of proton--proton collision data, collected during 2015 and 2016 at a centre-of-mass energy $\sqrt{s}=13$ TeV by the ATLAS detector at the Large Hadron Collider, which correspond to an integrated luminosity of 14.7 fb$^{-1}$, Both searches target the pair production of supersymmetric particles, squarks or gluinos, which decay to final states containing a same-flavour opposite-sign lepton pair via one of two mechanisms: a leptonically decaying Z boson in the final state, leading to a peak in the dilepton invariant-mass distribution around the Z boson mass; and decays of neutralinos (e.g. $\tilde{\chi}_2^0 \rightarrow \ell^+\ell^- \tilde{\chi}_1^0$), yielding a kinematic endpoint in the dilepton invariant-mass spectrum. The data are found to be consistent with the Standard Model expectation. Results are interpreted in simplified models of gluino-pair (squark-pair) production, and provide sensitivity to gluinos (squarks) with masses as large as 1.70 TeV (980 GeV).publishedVersio