320 research outputs found

    Noise Effects on a Proposed Algorithm for Signal Reconstruction and Bandwidth Optimization

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    The development of wireless technology in recent years has increased the demand for channel resources within a limited spectrum. The system\u27s performance can be improved through bandwidth optimization, as the spectrum is a scarce resource. To reconstruct the signal, given incomplete knowledge about the original signal, signal reconstruction algorithms are needed. In this paper, we propose a new scheme for reducing the effect of adding additive white Gaussian noise (AWGN) using a noise reject filter (NRF) on a previously discussed algorithm for baseband signal transmission and reconstruction that can reconstruct most of the signal’s energy without any need to send most of the signal’s concentrated power like the conventional methods, thus achieving bandwidth optimization. The proposed scheme for noise reduction was tested for a pulse signal and stream of pulses with different rates (2, 4, 6, and 8 Mbps) and showed good reconstruction performance in terms of the normalized mean squared error (NMSE) and achieved an average enhancement of around 48%. The proposed schemes for signal reconstruction and noise reduction can be applied to different applications, such as ultra-wideband (UWB) communications, radio frequency identification (RFID) systems, mobile communication networks, and radar systems

    Hiding data in images using steganography techniques with compression algorithms

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    Steganography is the science and art of secret communication between two sides that attempt to hide the content of the message. It is the science of embedding information into the cover image without causing a loss in the cover image after embedding.Steganography is the art and technology of writing hidden messages in such a manner that no person, apart from the sender and supposed recipient, suspects the lifestyles of the message. It is gaining huge attention these days as it does now not attract attention to its information's existence. In this paper, a comparison of two different techniques is given. The first technique used Least Significant Bit (LSB) with no encryption and no compression. In the second technique, the secret message is encrypted first then LSB technique is applied. Moreover, Discrete Cosine Transform (DCT) is used to transform the image into the frequency domain. The LSB algorithm is implemented in spatial domain in which the payload bits are inserted into the least significant bits of cover image to develop the stego-image while DCT algorithm is implemented in frequency domain in which the stego-image is transformed from spatial domain to the frequency domain and the payload bits are inserted into the frequency components of the cover image.The performance of these two techniques is evaluated on the basis of the parameters MSE and PSNR

    Throttling effect on the performance and emissions of a multi-cylinder gasoline fuelled spark ignition engine

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    The throttle mechanism, a regulatory technique of engine output, is accompanied by a loss of some energy. The effect of intake air throttling on the performance and emissions of a multi-cylinder spark ignition gasoline engine was experimentally investigated. The engine was coupled to a hydraulic dynamometer equipped with a customized cooling system for both the engine and dynamometer. Experimental tests were performed for various engine speeds and air-fuel ratios at the WOT and POT conditions with optimized ignition timing. The acquired results recorded that a better engine operation could be achieved with WOT in terms of bmep, bsfc, ηb, CO, CO2 and UHC compared to POT. At the same time, the worst trend at WOT was noticed for the NOx concentration due to the higher conversion efficiency of fuel combustion. In terms of engine speed for both WOT and POT conditions, operating at 3000 rpm represents the minima of ϕ, bsfc, CO and UHC; and the maxima of ηb, CO2 and NOx with some fluctuation on both sides of this point. Maximum recorded values of ηb were about 30.55% and 28. 55%, while the minimum values of bsfc were about 274 and 293 g/kW.h for the WOT and POT conditions, respectively. The maximum bmep was obtained at 2500 rpm at WOT and POT conditions with values of about 940 kPa and 904 kPa, respectively. Maximum recorded values of NOx were about 1525 and 977 ppm for the WOT and POT conditions, respectively

    Sect and House in Syria: History, Architecture, and Bayt Amongst the Druze in Jaramana

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    This paper explores the connections between the architecture and materiality of houses and the social idiom of bayt (house, family). The ethnographic exploration is located in the Druze village of Jaramana, on the outskirts of the Syrian capital Damascus. It traces the histories, genealogies, and politics of two families, bayt Abud-Haddad and bayt Ouward, through their houses. By exploring the two families and the architecture of their houses, this paper provides a detailed ethnographic account of historical change in modern Syria, internal diversity, and stratification within the intimate social fabric of the Druze neighbourhood at a time of war, and contributes a relational approach to the anthropological understanding of houses

    Constitutive expression of CD26/dipeptidylpeptidase IV on peripheral blood B lymphocytes of patients with B chronic lymphocytic leukaemia

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    We have investigated the expression of the ectoenzyme dipeptidylpeptidase IV (DPP IV)/CD26 on lymphocytes obtained from patients with B chronic lymphocytic leukaemia (B-CLL) and compared it with healthy subjects. Using two-colour immunofluorescence analysis with CD26 and CD20 or CD23 monoclonal antibodies, CD26 was found undetectable on peripheral resting B-cells (CD20+ CD23−) from normal donors whereas it was expressed on B-cells activated in vitro with interleukin (IL)-4 and Staphylococcus aureus strain cowan I (CD20+ CD23+). The expression of CD26 on leukaemic B-cells (CD20+ CD23+) was clearly induced in 22 out of 25 patients examined. Consequently, induced levels of CD26 cell surface expression on either normal activated and malignant B-cells coincided with the enhancement of DPP IV activity detected on the surface of these cells. Reverse transcription polymerase chain reaction analyses showed that the transcript levels of the CD26 gene was higher in normal activated B-cells and B-CLL cells than in resting B-cells, suggesting that CD26 was expressed at the level of transcriptional activation. These observations provide evidence of the abnormal expression of DPPIV/CD26 in B-CLL which, therefore, may be considered as a novel marker for B-CLL. Further investigation in relation to CD26 expression and other B malignancies needs to be defined. © 1999 Cancer Research Campaig

    Standardizing definitions and reporting guidelines for the infertility core outcome set : an international consensus development study

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    Acknowledgments We would like to thank the consensus development meeting participants and colleagues at the Cochrane Gynaecology and Fertility Group, University of Auckland, New Zealand. Funding This research was funded by the Catalyst Fund, Royal Society of New Zealand, Auckland Medical Research Fund and Maurice and Phyllis Paykel Trust. The funder had no role in the design and conduct of the study, the collection, management, analysis or interpretation of data or manuscript preparation. Siladitya Bhattacharya was supported by the University of Auckland Foundation Seelye Travelling Fellowship. B.W.M. is supported by a National Health and Medical Research Council Practitioner Fellowship (GNT1082548) This article has not been externally peer reviewed. This article has been published simultaneously in Fertility and SterilityPeer reviewedPublisher PD

    The General Transcriptional Repressor Tup1 Is Required for Dimorphism and Virulence in a Fungal Plant Pathogen

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    A critical step in the life cycle of many fungal pathogens is the transition between yeast-like growth and the formation of filamentous structures, a process known as dimorphism. This morphological shift, typically triggered by multiple environmental signals, is tightly controlled by complex genetic pathways to ensure successful pathogenic development. In animal pathogenic fungi, one of the best known regulators of dimorphism is the general transcriptional repressor, Tup1. However, the role of Tup1 in fungal dimorphism is completely unknown in plant pathogens. Here we show that Tup1 plays a key role in orchestrating the yeast to hypha transition in the maize pathogen Ustilago maydis. Deletion of the tup1 gene causes a drastic reduction in the mating and filamentation capacity of the fungus, in turn leading to a reduced virulence phenotype. In U. maydis, these processes are controlled by the a and b mating-type loci, whose expression depends on the Prf1 transcription factor. Interestingly, Δtup1 strains show a critical reduction in the expression of prf1 and that of Prf1 target genes at both loci. Moreover, we observed that Tup1 appears to regulate Prf1 activity by controlling the expression of the prf1 transcriptional activators, rop1 and hap2. Additionally, we describe a putative novel prf1 repressor, named Pac2, which seems to be an important target of Tup1 in the control of dimorphism and virulence. Furthermore, we show that Tup1 is required for full pathogenic development since tup1 deletion mutants are unable to complete the sexual cycle. Our findings establish Tup1 as a key factor coordinating dimorphism in the phytopathogen U. maydis and support a conserved role for Tup1 in the control of hypha-specific genes among animal and plant fungal pathogens

    Fortunella margarita Transcriptional Reprogramming Triggered by Xanthomonas citri subsp. citri

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    <p>Abstract</p> <p>Background</p> <p>Citrus canker disease caused by the bacterial pathogen <it>Xanthomonas citri </it>subsp. <it>citri (</it>Xcc) <it>has </it>become endemic in areas where high temperature, rain, humidity, and windy conditions provide a favourable environment for the dissemination of the bacterium. Xcc is pathogenic on many commercial citrus varieties but appears to elicit an incompatible reaction on the citrus relative <it>Fortunella margarita </it>Swing (kumquat), in the form of a very distinct delayed necrotic response. We have developed subtractive libraries enriched in sequences expressed in kumquat leaves during both early and late stages of the disease. The isolated differentially expressed transcripts were subsequently sequenced. Our results demonstrate how the use of microarray expression profiling can help assign roles to previously uncharacterized genes and elucidate plant pathogenesis-response related mechanisms. This can be considered to be a case study in a citrus relative where high throughput technologies were utilized to understand defence mechanisms in <it>Fortunella </it>and citrus at the molecular level.</p> <p>Results</p> <p><b>cDNAs from sequenced kumquat libraries (ESTs) made from subtracted RNA populations, healthy vs. infected, were used to make this microarray</b>. Of 2054 selected genes on a customized array, 317 were differentially expressed (P < 0.05) in Xcc challenged kumquat plants compared to mock-inoculated ones. This study identified components of the incompatible interaction such as reactive oxygen species (ROS) and programmed cell death (PCD). Common defence mechanisms and a number of resistance genes were also identified. In addition, there were a considerable number of differentially regulated genes that had no homologues in the databases. This could be an indication of either a specialized set of genes employed by kumquat in response to canker disease or new defence mechanisms in citrus.</p> <p>Conclusion</p> <p>Functional categorization of kumquat Xcc-responsive genes revealed an enhanced defence-related metabolism as well as a number of resistant response-specific genes in the kumquat transcriptome in response to Xcc inoculation. Gene expression profile(s) were analyzed to assemble a comprehensive and inclusive image of the molecular interaction in the kumquat/Xcc system. This was done in order to elucidate molecular mechanisms associated with the development of the hypersensitive response phenotype in kumquat leaves. These data will be used to perform comparisons among citrus species to evaluate means to enhance the host immune responses against bacterial diseases.</p

    p16INK4A Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1

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    /pRB/E2F pathway, a key regulator of the critical G1 to S phase transition of the cell cycle, is universally disrupted in human cancer. However, the precise function of the different members of this pathway and their functional interplay are still not well defined. -dependent manner, and several of these genes are also members of the AUF1 and E2F1 regulons. We also present evidence that E2F1 mediates p16-dependent regulation of several pro- and anti-apoptotic proteins, and the consequent induction of spontaneous as well as doxorubicin-induced apoptosis. is also a modulator of transcription and apoptosis through controlling the expression of two major transcription regulators, AUF1 and E2F1
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