Features of elementary burst formation during cutting coals and isotropic materials with reference cutting tool of mining machines

The paper considers the cutting of brittle coals and rocks by a single cutter of a mining machine, in contrast to the generally accepted integral approach, different from the standpoint of the formation of successive elementary bursts that make up the cut. The process of the formation of an elementary bust in time is viewed as successive phases. Due to the complexity and multi-factor nature of the process, preference is given to experimental bench studies using reference cutters, isotropic materials, and real rock blocks. The bursting parameters values greatly influence the time of static forces action, the peculiarities of the formation of stress fields in the undercutter zone of the rock mass and the conditions for the emergence and development of main cracks in the near-cut zones during the cutting process. The accepted phase-energy method of analyzing the process, which most closely matches the structure of the studied process, revealed a more significant, than previously expected, effect on the cutting process, variability of cutting speed and potential energy reserve in the cutter drive. The paper discusses the possibility of purposeful formation of the parameters of elementary bursts. It describes new ways to improve the efficiency of cutting coal and rocks, in particular, reducing the maximum loads and specific energy consumption. It also considers the possibility of reducing the grinding of the rock mass and dust formation

New quinazolinone-based Mannich bases: Synthesis and in vitro cytotoxic evaluation

This research presents the synthesis of new quinazolinone-based Mannich bases in good yields via a three-step procedure. The first step is the reaction of 6-hydroxyanthranilic acid 1 with an excess of acetic anhydride at 150°C for 2 h to afford benzoxazinone 2 in 87% yield. Compound 2 is then reacted with 4-aminophenol in DMSO at reflux for 7 h to give compound 3 in 75% yield. Finally, the reaction of 3 with paraformadehyde and secondary amines in ethanol affords new quinazolinone-based Mannich bases 4a-c and 5a-e in 55-70% yields. The structure of Mannich bases have been characterized by NMR and MS spectra. The bio-assay results show that some new Mannich bases exhibited weak to moderate cytotoxic activity against SKLu-1 and MCF-7 cell lines

A Study Of UV-curable Offset Ink Emulsified With An Alternative Isopropyl Alcohol-free Fountain Solution

In the present research, fountain solution without isopropyl alcohol (IPA) for Ultraviolet offset curing ink (UV ink) was prepared by using Ethylene Glycol Mono-butyl Ether (EGME) as a substitute for IPA. The effect of EGME concentration on the water pick-up characteristics, tack value, rheological behaviors, and curing time of UV offset inks was investigated. Water pick-up characteristics, tack value and rheological behaviors were measured by Duke Ink water emulsification tester, Tack-o-scope and cone-plate rheometer, respectively. The curing time of the UV ink was evaluated by the rub test of printed sheet samples proofed on the polymer film at the standard solid ink density and the same ink thickness. The results revealed that an increase in EGME concentration increased the water pick-up characteristics of the UV ink. There was no significant influence of EGME on the tack value of UV inks. However, the tack value of UV ink was significantly affected by fountain concentration in UV inks and UV ink color. The addition of EGME reduced the dynamic viscosity and thixotropic property of UV inks but did not change the flow behavior of UV ink as shear thinning. This study indicates that UV ink emulsified with a higher EGME concentration fountain solution needs a longer curing time. The cyan UV ink has the longest curing time. Finally, the fountain solution of 10% EGME exhibited good performance in water pick-up characteristics, tack value, rheological behaviors, and curing time of UV inks

Cost optimization of two-stage helical gearboxes with second stage double gear-sets

In practice, the cost of a gearbox plays a very important role in the trade. Therefore, reducing the cost of gearboxes is an important task not only when manufacturing the gearboxes but also when designing them. In order to reduce the cost of a gearbox, there are many solutions in which determining the optimal partial gear ratios of a gearbox is an effective measure. This is because it not only the size, the mass but also the cost of a gearbox depends greatly on the partial gear ratios. This work presents a method for calculating the cost function of two-stage helical gearboxes with second-stage double gear-sets based on the mass of the components that construct the gearbox. The cost objective function is minimized to achieve the optimal transmission ratios. Furthermore, screening experiments are carried out with nine important input parameters that have significant effects on the optimum transmission ratio of the second stage. These parameters are the total gearbox ratio, the coefficient of wheel face width of the first stage, coefficient of wheel face width of the second stage, the allowable contact stress of the first stage, the allowable contact stress of the second stage, the output torque, the cost of gearbox housing, the cost of gears, and the shaft cost. The experimental results of were analysed by using the Analysis of Variance (ANOVA) method with the help of Minitab 19 software. The results demonstrate that the effective weight of the input parameters and their interactions on the output response was investigated. Also, a regression model for computing the optimal transmission ratio of the second stage was proposed. This brings significance not only in the design process but also in manufacturing since the gearbox cost can decreas

Extracting Conditions Optimization and Bioactivity of Polysaccharides from the Pods of Haricot Vert

Polysaccharides from the pods of haricot vert (Phaseolus vulgaris L.) were extracted using a simple heating method, by varying extracting temperature, heating time, solid-to-liquid ratio, and solvent compositions. The obtained results were processed using statistical analysis that helped to identify the optimal conditions for the polysaccharides’ extraction process. This study represents a promising production method of bioactive polysaccharides extract in the food and pharmaceutical industry

Network Coding with Multimedia Transmission and Cognitive Networking: An Implementation based on Software-Defined Radio

Network coding (NC) is considered a breakthrough to improve throughput, robustness, and security of wireless networks. Although the theoretical aspects of NC have been extensively investigated, there have been only few experiments with pure NC schematics. This paper presents an implementation of NC under a two-way relay model and extends it to two non-straightforward scenarios: (i) multimedia transmission with layered coding and multiple-description coding, and (ii) cognitive radio with Vandermonde frequency division multiplexing (VFDM). The implementation is in real time and based on software-defined radio (SDR). The experimental results show that, by combining NC and source coding, we can control the quality of the received multimedia content in an on-demand manner. Whereas in the VFDM-based cognitive radio, the quality of the received content in the primary receiver is low (due to imperfect channel estimation) yet retrievable. Our implementation results serve as a proof for the practicability of network coding in relevant applications

Network Coding with Multimedia Transmission and Cognitive Networking: An Implementation based on Software-Defined Radio

Network coding (NC) is considered a breakthrough to improve throughput, robustness, and security of wireless networks. Although the theoretical aspects of NC have been extensively investigated, there have been only few experiments with pure NC schematics. This paper presents an implementation of NC under a two-way relay model and extends it to two\ua0non-straightforward scenarios: (i) multimedia transmission with layered coding and multiple-description coding, and (ii) cognitive radio with Vandermonde frequency division multiplexing (VFDM). The implementation is in real time and based on software-defined radio (SDR). The experimental results show that, by combining NC and source coding, we can control the quality of the received multimedia content in an on-demand manner. Whereas in the VFDM-based cognitive radio, the quality of the received content in the primary receiver is low (due to imperfect channel estimation) yet retrievable. Our implementation results serve as a proof for the practicability of network coding in relevant applications

Non-Invasive Prenatal Testing (NIPT) Implementation in Japan: A Comparison with the United Kingdom, Germany, Italy, Sweden, and Taiwan

Abstract: Introduction: The Non-Invasive Prenatal Testing (NIPT) guideline was issued and applied in 2013 by the Japanese Medical Association. Since being issued, the NIPT practice in Japan still has some problems related to indication, access, cost coverage and uniformity. Therefore, our study aimed to identify the Japanese challenges of adopting NIPT into prenatal diagnosis by comparing the system and process with other countries. Method: The United Kingdom, Germany, Italy, Sweden, and Taiwan were purposefully selected for comparison. All the countries, including Japan, introduced NIPT. The literature and information searches were conducted using PubMed, SCOPUS, Google Scholar, CiNii and Google searching engine. Results: The process of NIPT in Japan was very different from the other countries. Japan is the only country that indicated NIPT for only pregnant women over 35 years old in certificated facilities and did not have a policy regarding providing information on prenatal screening and NIPT to all women. Japan also did not have a policy regarding abortion due to fetal abnormalities. The practice of NIPT guidelines is different between non-certified and certified facilities. NIPT fee was the highest in Japan and was not covered by insurance. Conclusion: Pregnant women in Japansuffered from disparities in information access, economic burden, geographic location, and practice of NIPT guidelines between the certified and the non-certified facilities. Pregnant women-centered prenatal diagnosis policy, including NIPT, should be established in Japan by learning cases from other countries

Factors affecting consumer’s bargaining behavior: The case of fashionable clothing

Shopping is one of the current trends of the Vietnamese. According to Nielsen’s research results about consumer confidence in the fourth quarter of 2017, more than half of Vietnamese people (51%) use their spare money to buy new clothes at modern business models such as supermarkets, shopping centers, or at very traditional models like street vendors and wet markets where haggling (also known as bargaining) is considered as a common habit for Vietnamese. This is due to business characteristics from a very long time ago in Viet Nam. The bargaining behavior is not so hard to recognize in shopping. Even now, a large part of foreign tourists is familiar with the bargaining culture. This study aimed to discover bargaining behavior, the factors affecting such a behavior in buying fashionable clothing of the consumers in Ho Chi Minh City, and to consider whether the differences in bargaining behavior exist among different groups of gender, age, and income. The research was conducted using mixed methods concluding qualitative research (in-depth interview and focus group) and quantitative one (survey). The results showed that Attitude towards bargaining, Perceived behavioral control, Interest in bargaining affect Consumer’s bargaining behavior when buying fashionable clothes. Results were validated in Ho Chi Minh City context, and some conclusions were also presented