Evaluation of seals, lubricants, and adhesives used on LDEF

A wide variety of seals, lubricants, and adhesives were used on the Long Duration Exposure Facility (LDEF). The results, to date, of the Systems Special Investigation Group (SIG) and the Materials SIG investigation into the effect of the long term low Earth orbit (LEO) exposure on these materials is discussed. Results of this investigation show that if the material was shielded from exposure to LDEF's external environment, the 69 month exposure to LEO had minimal effect on the material. However, if the material was on LDEF's exterior surface, a variety of events occurred ranging from no material change, to changes in mechanical or physical properties, to complete disappearance of the material. The results are from the following sources: (1) visual examinations and/or testing of materials performed by various LDEF experimenters, (2) testing done at Boeing in support of the Materials or Systems SIG investigations, (3) testing done at Boeing on Boeing hardware flown on LDEF

Grazing Incidence X-ray Studies of Ultra-Thin Lumogen Films

Lumogen® Yellow S0790 films have been produced on silicon wafer substrates via physical vapour deposition (PVD) and spin-coating (SC) methods. These coatings were characterised with X-ray reflectometry (XRR) and grazing incidence X-ray diffraction (GIXD) techniques. The results show that ultra-thin (less than 12nm) PVD films coat amorphously, with crystallinity becoming increasingly apparent with increasing film thickness. In contrast, measurements of ultra-thin (less than 2nm) spin-coated films reveal a second, apparently stable crystalline structure. © 2007, Elsevier Ltd

Monitoring ecological impacts: concepts and practice in flowing waters

Monitoring Ecological Impacts provides the tools needed to design&nbsp; assessment programs that can reliably monitor, detect and allow&nbsp; management of human impacts on the natural environment. The procedures described are well-grounded in inferential logic. Step-by-step guidelines and flow diagrams provide clear and useable protocols, which are applicable to real situations.<br /

AlleleAnalyzer: a tool for personalized and allele-specific sgRNA design.

The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles differing by even a single base pair. Target sites might carry genetic variations that are not distinguishable by sgRNA designing tools based on one reference genome. AlleleAnalyzer is an open-source software that incorporates single-nucleotide variants and short insertions and deletions to design sgRNAs for precisely editing 1 or multiple haplotypes of a sequenced genome, currently supporting 11 Cas proteins. It also leverages patterns of shared genetic variation to optimize sgRNA design for different human populations. AlleleAnalyzer is available at https://github.com/keoughkath/AlleleAnalyzer

ExcisionFinder Data

ExcisionFinder is a database and toolset for analysis and design of allele-specific CRISPR editing that leverages >2,500 human genomes to estimate feasibility of allele-specific loci in varied individuals and design allele-specific sgRNAs in individual genomes