Tl’azt’en Learning Circle: Information Technology, Health and Cultural Preservation

A Community Learning Centre (CLC) is an innovative model of delivering health care and health information based firmly on the idea of community engagement. It has two interrelated components: 1) a community-based facility with Internet-linked computers accessible to all community members; and 2) community developed web-based resources relevant to community defined needs and priorities. This article describes a pilot CLC implementation in a remote British Columbia First Nations community. A CLC supports the acquisition of health information as well as research and technology skills by facilitating access to, and uptake of, relevant resources developed by and for community members

Aboriginal children and family connections to primary health care whilst homeless and in high housing mobility: observations from a Nurse Practitioner-led service

Aim: This article documents the impact of a Nurse Practitioner-led primary health service for disadvantaged children living in housing instability or homelessness. It identifies that First Nations children miss out on essential primary care, particularly immunisation, but have less severe health conditions than non-First Nations children living in housing insecurity. Background: Health services for homeless populations focus on the 11% of rough sleepers, little is done for the 22% of children in Australia living in housing instability; many of whom are from First Nations families. Little is known of the health status of these children or their connections to appropriate primary health care. Methods: This research implemented an innovative model of extended health care delivery, embedding a Nurse Practitioner in a homeless service to work with families providing health assessments and referrals, using clinically validated assessment tools. This article reports on proof of concept findings on the service that measured immunisation rates, developmental, medical, dental and mental health needs of children, particularly First Nations children, using a three-point severity level scale with Level 3 being the most severe and in need of immediate referral to a specialist medical service. Findings: Forty-three children were referred by the service to the Nurse Practitioner over a 6-month period, with nine identifying as First Nations children. Differences in severity levels between First Nations/non-First Nations children were Level 1, First Nations/non-First Nations 0/15%; Level 2, 10/17%; and Level 3, 45/29%. Forty-five percent of First Nations children had no health problems, as compared to 29% on non-First Nations children. Immunisation rates were low for both cohorts. No First Nations child was immunised and only 9% of the non-First Nations children. While numbers for both cohorts are too low for valid statistical analysis, the lower levels of severity for First Nations children suggest stronger extended family support and the positive impact of cultural norms of reciprocity

Ghost direction detection and other innovations for Ms. Pac-Man

Ms. Pac-Man was developed in the 1980s, becoming one of the most popular arcade games of its time. It still has a significant following today and has recently attracted the attention of artificial intelligence researchers, in part, due to the fact that the agent must react in real time in order to navigate its way through the maze. This pape

Resolved stellar mass maps of galaxies. I: method and implications for global mass estimates

(Abridged) We introduce a novel technique to construct spatially resolved maps of stellar mass surface density in galaxies based on optical and near IR imaging. We use optical/NIR colour(s) to infer effective stellar mass-to-light ratios (M/L) at each pixel, which are then multiplied by the surface brightness to obtain the local stellar surface mass density. We build look-up tables to express M/L as a function of colour(s) by marginalizing over a Monte Carlo library of 50,000 stellar population synthesis (SPS) models by Charlot & Bruzual (2007), which include a revised prescription for the TP-AGB stellar evolutionary phase, with a wide range of dust exinctions. In order to extract reliable flux and colour information at any position in the galaxy, we perform a median adaptive smoothing of the images that preserves the highest possible spatial resolution. As the most practical and robust, and hence fiducial method, we express the M/L in the H band as a function of (g-i) and (i-H). Stellar mass maps computed in this way have a typical accuracy of 30 per cent or less at any given pixel, determined from the scatter in the models. We compare maps obtained with our fiducial method with those derived using other combinations of bandpasses and the old BC03 TP-AGB prescription. Finally, we compare total stellar mass estimates obtained by integrating resolved mass maps with those obtained with unresolved photometry. In galaxies with evident dust lanes, unresolved estimates may miss up to 40 per cent of the total stellar mass because dusty regions are strongly under-represented in the luminous fluxes.Comment: Accepted for publication on MNRAS on Aug 10th 2009. 21 pages, 14 figures (see http://www.mpia.de/homes/zibetti/mass_maps_I.pdf for full resolution). One appendix added and minor changes done wrt to original submissio

Spiral structure in nearby galaxies I. Sample, data analysis, and overview of results

This paper, the first of two, introduces an observational study of spiral structure in galaxies chosen from the SINGS survey. Near infrared (NIR) and optical data are used to produce mass surface density maps, and from these the morphology of the disc is examined. The aim of this work is to characterise the prevalence of spiral structure in this sample and, in the cases where a clear spiral pattern is found, include the findings in a comparative study (reported in paper II). A two-armed (`grand design') spiral pattern is found in approximately half the galaxies studied, including all those that are designated as grand design in the optical, but also including some, but not all, optically flocculent galaxies. It is found that the level of non-axisymmetric structure in the galaxies' mass distributions is only modestly higher in those galaxies that are classified as `grand design' compared with those that are not, implying that non-grand design galaxies possess significant power in higher order modes. There is no evidence that bars preferentially trigger the spirals, but they do appear to stir up non-axisymmetric structure in the disc. In contrast, there is evidence that strong/close tidal interactions with companion galaxies are associated with strong two-armed spiral structure in the infrared, though there are a number of galaxies with relatively weak infrared spiral structure that do not possess such companions.Comment: 28 pages, 56 figures. Accepted for publication in MNRA

Osteology and relationships of Rhinopycnodus gabriellae gen. et sp. nov. (Pycnodontiformes) from the marine Late Cretaceous of Lebanon

The osteology of Rhinopycnodus gabriellae gen. and sp. nov., a pycnodontiform fish from the marine Cenomanian (Late Cretaceous) of Lebanon, is studied in detail. This new fossil genus belongs to the family Pycnodontidae, as shown by the presence of a posterior brush-like process on its parietal. Its long and broad premaxilla, bearing one short and very broad tooth is the principal autapomorphy of this fish. Within the phylogeny of Pycnodontidae, Rhinopycnodus occupies an intermediate position between Ocloedus and Tepexichthys

What\u27s going well: a qualitative analysis of positive patient and family feedback in the context of the diagnostic process

OBJECTIVES: Accurate and timely diagnosis relies on close collaboration between patients/families and clinicians. Just as patients have unique insights into diagnostic breakdowns, positive patient feedback may also generate broader perspectives on what constitutes a good diagnostic process (DxP). METHODS: We evaluated patient/family feedback on what\u27s going well as part of an online pre-visit survey designed to engage patients/families in the DxP. Patients/families living with chronic conditions with visits in three urban pediatric subspecialty clinics (site 1) and one rural adult primary care clinic (site 2) were invited to complete the survey between December 2020 and March 2022. We adapted the Healthcare Complaints Analysis Tool (HCAT) to conduct a qualitative analysis on a subset of patient/family responses with ≥20 words. RESULTS: In total, 7,075 surveys were completed before 18,129 visits (39 %) at site 1, and 460 surveys were completed prior to 706 (65 %) visits at site 2. Of all participants, 1,578 volunteered positive feedback, ranging from 1-79 words. Qualitative analysis of 272 comments with ≥20 words described: Relationships (60 %), Clinical Care (36 %), and Environment (4 %). Compared to primary care, subspecialty comments showed the same overall rankings. Within Relationships, patients/families most commonly noted: thorough and competent attention (46 %), clear communication and listening (41 %) and emotional support and human connection (39 %). Within Clinical Care, patients highlighted: timeliness (31 %), effective clinical management (30 %), and coordination of care (25 %). CONCLUSIONS: Patients/families valued relationships with clinicians above all else in the DxP, emphasizing the importance of supporting clinicians to nurture effective relationships and relationship-centered care in the DxP

Tracing spiral density waves in M81

We use SPITZER IRAC 3.6 and 4.5micron near infrared data from the Spitzer Infrared Nearby Galaxies Survey (SINGS), optical B, V and I and 2MASS Ks band data to produce mass surface density maps of M81. The IRAC 3.6 and 4.5micron data, whilst dominated by emission from old stellar populations, is corrected for small-scale contamination by young stars and PAH emission. The I band data are used to produce a mass surface density map by a B-V colour-correction, following the method of Bell and de Jong. We fit a bulge and exponential disc to each mass map, and subtract these components to reveal the non-axisymmetric mass surface density. From the residual mass maps we are able to extract the amplitude and phase of the density wave, using azimuthal profiles. The response of the gas is observed via dust emission in the 8micron IRAC band, allowing a comparison between the phase of the stellar density wave and gas shock. The relationship between this angular offset and radius suggests that the spiral structure is reasonably long lived and allows the position of corotation to be determined.Comment: 15 pages, 17 figures, accepted for publication in MNRA

The Flint Food Store Survey: combining spatial analysis with a modified Nutrition Environment Measures Survey in Stores (NEMS-S) to measure the community and consumer nutrition environments

Objective The goal of the present study was to use a methodology that accurately and reliably describes the availability, price and quality of healthy foods at both the store and community levels using the Nutrition Environment Measures Survey in Stores (NEMS-S), to propose a spatial methodology for integrating these store and community data into measures for defining objective food access. Setting Two hundred and sixty-five retail food stores in and within 2 miles (3·2 km) of Flint, Michigan, USA, were mapped using ArcGIS mapping software. Design A survey based on the validated NEMS-S was conducted at each retail food store. Scores were assigned to each store based on a modified version of the NEMS-S scoring system and linked to the mapped locations of stores. Neighbourhood characteristics (race and socio-economic distress) were appended to each store. Finally, spatial and kernel density analyses were run on the mapped store scores to obtain healthy food density metrics. Results Regression analyses revealed that neighbourhoods with higher socio-economic distress had significantly lower dairy sub-scores compared with their lower-distress counterparts (β coefficient=−1·3; P=0·04). Additionally, supermarkets were present only in neighbourhoods with \u3c60 % African-American population and low socio-economic distress. Two areas in Flint had an overall NEMS-S score of 0. Conclusions By identifying areas with poor access to healthy foods via a validated metric, this research can be used help local government and organizations target interventions to high-need areas. Furthermore, the methodology used for the survey and the mapping exercise can be replicated in other cities to provide comparable results

Menopause induces changes to the stratum corneum ceramide profile, which are prevented by hormone replacement therapy

Abstract The menopause can lead to epidermal changes that are alleviated by hormone replacement therapy (HRT). We hypothesise that these changes could relate to altered ceramide production, and that oestrogen may have a role in keratinocyte ceramide metabolism. White Caucasian women were recruited into three groups: pre-menopausal (n = 7), post-menopausal (n = 11) and post-menopausal taking HRT (n = 10). Blood samples were assessed for hormone levels, transepidermal water loss was measured to assess skin barrier function, and stratum corneum lipids were sampled from photoprotected buttock skin. Ceramides and sphingomyelins were analysed by ultraperformance liquid chromatography with electrospray ionisation and tandem mass spectrometry. Post-menopausal stratum corneum contained lower levels of ceramides, with shorter average length; changes that were not evident in the HRT group. Serum oestradiol correlated with ceramide abundance and length. Ceramides had shorter sphingoid bases, indicating altered de novo ceramide biosynthesis. Additionally, post-menopausal women had higher sphingomyelin levels, suggesting a possible effect on the hydrolysis pathway. Treatment of primary human keratinocytes with oestradiol (10 nM) increased production of CER[NS] and CER[NDS] ceramides, confirming an effect of oestrogen on cutaneous ceramide metabolism. Taken together, these data show perturbed stratum corneum lipids post-menopause, and a role for oestrogen in ceramide production