9 research outputs found

    Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

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    West Africa is currently witnessing the most extensive Ebola virus (EBOV) outbreak so far recorded. Until now, there have been 27,013 reported cases and 11,134 deaths. The origin of the virus is thought to have been a zoonotic transmission from a bat to a two-year-old boy in December 2013 (ref. 2). From this index case the virus was spread by human-to-human contact throughout Guinea, Sierra Leone and Liberia. However, the origin of the particular virus in each country and time of transmission is not known and currently relies on epidemiological analysis, which may be unreliable owing to the difficulties of obtaining patient information. Here we trace the genetic evolution of EBOV in the current outbreak that has resulted in multiple lineages. Deep sequencing of 179 patient samples processed by the European Mobile Laboratory, the first diagnostics unit to be deployed to the epicentre of the outbreak in Guinea, reveals an epidemiological and evolutionary history of the epidemic from March 2014 to January 2015. Analysis of EBOV genome evolution has also benefited from a similar sequencing effort of patient samples from Sierra Leone. Our results confirm that the EBOV from Guinea moved into Sierra Leone, most likely in April or early May. The viruses of the Guinea/Sierra Leone lineage mixed around June/July 2014. Viral sequences covering August, September and October 2014 indicate that this lineage evolved independently within Guinea. These data can be used in conjunction with epidemiological information to test retrospectively the effectiveness of control measures, and provides an unprecedented window into the evolution of an ongoing viral haemorrhagic fever outbreak.status: publishe

    GEOMORPHOLOGICAL MAPPING WITH TERRESTRIAL LASER SCANNING AND UAV-BASED IMAGING

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    High-resolution digital elevation models (DEMs) are useful for the detailed mapping of geomorphological features. Nowadays various sensors and platforms are available to collect 3D data. The presented study compares terrestrial laser scanning (TLS) and low-cost unmanned aerial vehicles (UAV)-based imaging in terms of their usability for capturing small-scale surface structures. In October 2014 and June 2015 measurements with both systems were carried out in an episodically water-filled karst depression under pasture farming in the region of Hohenlohe (Southwest Germany). The overall aims were to establish high-resolution DEMs and monitor changes of the relief caused by dissolution and compare the advantages and drawbacks of both systems for such studies. Due to the short time between the campaigns the clear detection of temporal changes was hardly possible. However, the multi-temporal campaigns allowed an extensive investigation of the usability of both sensors under different environmental conditions. In addition to the remote sensing measurements, the coordinates of several positions in the study area were measured with a RTK-DGPS system as independent reference data sets in both campaigns. The TLS- and UAV-derived DEM heights at these positions were validated against the DGPS-derived heights. The accuracy of the TLS-derived values is supported by low mean differences between TLS and DGPS measurements while the UAV-derived models show a weaker performance. In the future years additional simultaneous measurements with both approaches under more similar vegetation conditions are necessary to detect surface movements. Moreover, by investigating the subsurface the interaction of above and below ground processes might be detected

    The Holocene sea level story since 7500 BP - Lessons from the Eastern Mediterranean, the Black and the Azov Seas

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    This paper addresses the obvious controversy between the so far published sea level curves of the Black Sea and the Mediterranean. It starts with a discussion of the methods of reconstructing sea level curves, the evaluation of sea level indicators, and the application of the radiocarbon dating method. At least since 7500 BP, when the Black Sea and the Mediterranean were connected, both water bodies must have reacted synchronously on glacio-eustatic changes. It is documented that none of the Mediterranean sea level curves shows the major wiggles postulated for the Black Sea which are supposed to reflect trans- and regression cycles. The very shallow bathymetric condition of the Azov Sea and the northern Black Sea should have led to considerable and traceable shoreline displacements. There is neither archaeological nor historical evidence of mid- and late-Holocene regressions of several meters. The tectonic setting of the Black and Azov seas implicates that the tectonic signal often overrides the eustatic one. Therefore, only local sea level curves can be established. In this paper, based on vibracores, a locally valid sea level curve for the Taman Peninsula is demonstrated. Layers of paralic peat were used as sea level indicators and for C-14 dating. The shape of this curve follows the one known from the Mediterranean. This study also revealed that the present peninsula of Taman evolved out of a former archipelago. (C) 2009 Elsevier Ltd and INQUA. All rights reserved

    Halmyris: Geoarchaeology of a fluvial harbour on the Danube Delta (Dobrogea, Romania)

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    In Northern Dobrogea, north of the Dunavăţ promontory, the Roman fortress of Halmyris was founded in the late 1st century AD on a Getic settlement dating to the middle of the 1st millennium BC, probably associated with a Greek emporium of the Classical and Hellenistic periods. At the time of the foundation of Halmyris, the Danube delta had already prograded several kilometres to the east leading to the progressive retreat of the sea and the formation of a deltaic plain characterised by numerous lakes and river channels. Here, we present the results of a multiproxy study combining sedimentology and palaeoecology to (1) understand the evolution of fluvial landscapes around Halmyris since ca. 8000 years BP and (2) identify the fluvial palaeoenvironments close to the city in Getic/Greek and Roman times, in order to locate and characterise the waterfront and the harbour. Our overriding objective was to improve understanding of human–environment relations in river delta settings. We demonstrate that Halmyris, protected by the Danubian floods due to its location on a palaeo-cliff top, had direct access to the river. A secondary channel of the Saint George, flowing north of the site, has been elucidated between the 7th century BC and the 7th century AD and could have been used as a natural harbour

    Unique human immune signature of Ebola virus disease in Guinea

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