3,551 research outputs found
Running the United States-Mexican Border: 1909 through the Present
A very large number of films have been and continue to be made about the border by both the United States and Mexican film industries. This is due primarily to the highly unusual nature of the United States-Mexico border itself, and because of various factors ranging from the Mexican Revolution of 1910, to the emergence of Westerns as the primary product of the United States film industry, and other economic, sociocultural, and technological reasons. This study is dedicated to an overview of the border films and strives to explain some of the major cultural, technological, historical, and economic factors that spurred them. It is broadly divided into three sections. The first establishes the conventions of the border in the popular mind, focusing attention on the role first of mass-produced dime novels, and subsequently of popular films. The second section reviews some of the most salient of those border conventions. The third shows how contemporary Chicano/Latino border films function to subvert and debunk those same conventions. Numerous films from American and Mexican studios and by independent Chicano producers made between 1909 through the present are cited and reviewed in historical context
Adviser\u27s guide to health savings accounts
https://egrove.olemiss.edu/aicpa_guides/1452/thumbnail.jp
Bed Site Selection of Fawn Pronghorn in Custer State Park, South Dakota
We evaluated pronghorn (Antilocapra americana) fawn bedding site characteristics on a prairie and ponderosa pine (Pinus ponderosa) landscape interface in Custer State Park, South Dakota. We radio-marked 16 adult female pronghorn and collected bed site information from their fawns during 2007~2008. We compared bed site selection with random sites (n = 74) during 2 periods; the early hiding phase when fawns were 1 ~28 days of age (n = 23 bed sites) and the later group phase when fawns were 29~60 days of age (n = 52 bed sites). During the hiding phase fawns selected dry prairie-seminatural mixed grassland at the course-scale level; group phase fawns selected prairie dog (Cynomys ludoviciana) dominated grasslands and dry prairie-seminatural mixed grassland at the course-scale. Evaluation at the fine-scale indicated fawns during the group phase period selected bed sites that had greater forb cover and overs tory canopy cover of ponderosa pine trees compared to random sites. Management activities that promote a dynamic grassland ecosystem with patches of forb cover may enhance resources selected as bedding habitat by pronghorn fawns during the group phase period
Direct Global Measurements of Tropspheric Winds Employing a Simplified Coherent Laser Radar using Fully Scalable Technology and Technique
Innovative designs of a space-based laser remote sensing 'wind machine' are presented. These designs seek compatibility with the traditionally conflicting constraints of high scientific value and low total mission cost. Mission cost is reduced by moving to smaller, lighter, more off-the-shelf instrument designs which can be accommodated on smaller launch vehicles
Spectral degeneracy and escape dynamics for intermittent maps with a hole
We study intermittent maps from the point of view of metastability. Small
neighbourhoods of an intermittent fixed point and their complements form pairs
of almost-invariant sets. Treating the small neighbourhood as a hole, we first
show that the absolutely continuous conditional invariant measures (ACCIMs)
converge to the ACIM as the length of the small neighbourhood shrinks to zero.
We then quantify how the escape dynamics from these almost-invariant sets are
connected with the second eigenfunctions of Perron-Frobenius (transfer)
operators when a small perturbation is applied near the intermittent fixed
point. In particular, we describe precisely the scaling of the second
eigenvalue with the perturbation size, provide upper and lower bounds, and
demonstrate convergence of the positive part of the second eigenfunction
to the ACIM as the perturbation goes to zero. This perturbation and associated
eigenvalue scalings and convergence results are all compatible with Ulam's
method and provide a formal explanation for the numerical behaviour of Ulam's
method in this nonuniformly hyperbolic setting. The main results of the paper
are illustrated with numerical computations.Comment: 34 page
Lipidomic QTL in Diversity Outbred mice identifies a novel function for α/β hydrolase domain 2 (Abhd2) as an enzyme that metabolizes phosphatidylcholine and cardiolipin.
We and others have previously shown that genetic association can be used to make causal connections between gene loci and small molecules measured by mass spectrometry in the bloodstream and in tissues. We identified a locus on mouse chromosome 7 where several phospholipids in liver showed strong genetic association to distinct gene loci. In this study, we integrated gene expression data with genetic association data to identify a single gene at the chromosome 7 locus as the driver of the phospholipid phenotypes. The gene encodes α/β-hydrolase domain 2 (Abhd2), one of 23 members of the ABHD gene family. We validated this observation by measuring lipids in a mouse with a whole-body deletion of Abhd2. The Abhd2KO mice had a significant increase in liver levels of phosphatidylcholine and phosphatidylethanolamine. Unexpectedly, we also found a decrease in two key mitochondrial lipids, cardiolipin and phosphatidylglycerol, in male Abhd2KO mice. These data suggest that Abhd2 plays a role in the synthesis, turnover, or remodeling of liver phospholipids
INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants.
Genome-wide association studies reveal many non-coding variants associated with complex traits. However, model organism studies largely remain as an untapped resource for unveiling the effector genes of non-coding variants. We develop INFIMA, Integrative Fine-Mapping, to pinpoint causal SNPs for diversity outbred (DO) mice eQTL by integrating founder mice multi-omics data including ATAC-seq, RNA-seq, footprinting, and in silico mutation analysis. We demonstrate INFIMA\u27s superior performance compared to alternatives with human and mouse chromatin conformation capture datasets. We apply INFIMA to identify novel effector genes for GWAS variants associated with diabetes. The results of the application are available at http://www.statlab.wisc.edu/shiny/INFIMA/
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