5,949 research outputs found
Diffusion in a crowded environment
We analyze a pair of diffusion equations which are derived in the infinite
system--size limit from a microscopic, individual--based, stochastic model.
Deviations from the conventional Fickian picture are found which ultimately
relate to the depletion of resources on which the particles rely. The
macroscopic equations are studied both analytically and numerically, and are
shown to yield anomalous diffusion which does not follow a power law with time,
as is frequently assumed when fitting data for such phenomena. These anomalies
are here understood within a consistent dynamical picture which applies to a
wide range of physical and biological systems, underlining the need for clearly
defined mechanisms which are systematically analyzed to give definite
predictions.Comment: 4 pages, 3 figures, minor change
Probing Isospin Dynamics in Halo Nuclei
Nuclear many-body theory is used to study nuclear matter and finite nuclei at
extreme isospin. In-medium interactions in asymmetric nuclear matter are
obtained from (Dirac-) Brueckner theory. Neutron skin formation in Ni and Sn
isotopes is investigated by relativistic mean-field calculations in DDRH theory
with density dependent meson-nucleon vertices. Applications to light nuclei are
discussed with special emphasis on pairing and core polarization in weakly
bound nuclei. Approaches accounting for continuum coupling in dripline pairing
and core polarization are presented. Calculations for the halo nuclei B,
Be and C show that shell structures are dissolving when the
driplines are approached. Relativistic breakup data are well described by
eikonal calculations.Comment: 10 pages, 8 figure
RADIOLOGY & PHOTOGRAMMETRY - Photogrammetric Principles as Applyed in the Periapical Intra-oral Radiology: an evaluation of the accuracy and method reproducibility
The objective of this study was to evaluate the accuracy and reproducibility of
photogrammetric principles and techniques over periapical radiographic images.
Twelve stereoscopic radiographic pairs were obtained by means of an Auxiliary
Aiming Device (AAD) fixed to a human jaw. The best angle of convergence to
allow stereoscopy was verified to be 20°. The radiograph images were digitalized
on a photogrammetric scanner and the data transferred to a computer memory. For
each pair of images, ten readings of the coordinates of a same point were recorded.
The precision obtained for the measurements of X, Y, Z coordinates were
respectively 3 µm, 3 µm and 18 µm. The reproducibility of the experiment was
possible due to the high rigidity and stability of the device created to hold the X-ray
instrument in the right position. The method shows to be high accurate for radiodiagnosis
in three-dimensional periapical radiographic images
Presentation of CMV immediate-early antigen to cytolytic T lymphocytes is selectively prevented by viral genes expressed in the early phase
The regulation of antigen processing and presentation to MHC class I-restricted cytolytic T lymphocytes was studied in cells infected with murine cytomegalovirus. Recognition by cytolytic T lymphocytes of the phosphoprotein pp89, the immunodominant viral antigen expressed in the immediate-early phase of infection, was selectively prevented during the subsequent expression of viral early genes. The surface expression of MHC class I glycoproteins and their capacity to present externally added pp89-derived antigenic peptides were not affected. Because recognition of several other antigens occurred during the early phase, a general failure in processing and presentation was excluded. Since neither rate of synthesis, amount, stability, nor nuclear transport of pp89 was modified, the failure in recognition indicates a selective interference with pp89 antigen processing and presentation
Causally Linking Neural Dominance to Perceptual Dominance in a Multisensory Conflict
When different senses are in conflict, one sense may dominate the perception of other sense, but it is not known whether the sensory cortex associated with the dominant modality exerts directional influence, at the functional brain level, over the sensory cortex associated with the dominated modality; in short, the link between sensory dominance and neuronal dominance is not established. In a task involving audio-visual conflict, using magnetoencephalography recordings in humans, we first demonstrated that the neuronal dominance – auditory cortex functionally influencing visual cortex – was associated with the sensory dominance – sound qualitatively altering visual perception. Further, we found that pre-stimulus auditory-to-visual connectivity could predict the perceptual outcome on a trial-by-trial basis. Subsequently, we performed an effective connectivity-guided neurofeedback electroencephalography experiment and showed that participants who were briefly trained to increase the neuronal dominance from auditory to visual cortex showed higher sensory, i.e. auditory, dominance during the conflict task immediately after the training. These results shed new light into the interactive neuronal nature of multisensory integration and open up exciting opportunities by enhancing or suppressing targeted mental functions subserved by effective connectivity
Effect of Transition Magnetic Moments on Collective Supernova Neutrino Oscillations
We study the effect of Majorana transition magnetic moments on the flavor
evolution of neutrinos and antineutrinos inside the core of Type-II supernova
explosions. We find non-trivial collective oscillation effects relating
neutrinos and antineutrinos of different flavors, even if one restricts the
discussion to Majorana transition electromagnetic moment values that are not
much larger than those expected from standard model interactions and nonzero
neutrino Majorana masses. This appears to be, to the best of our knowledge, the
only potentially observable phenomenon sensitive to such small values of
Majorana transition magnetic moments. We briefly comment on the effect of Dirac
transition magnetic moments and on the consequences of our results for future
observations of the flux of neutrinos of different flavors from a nearby
supernova explosion.Comment: 11 pages,appendix added, version accepted in JCA
Approximating the Maximum Overlap of Polygons under Translation
Let and be two simple polygons in the plane of total complexity ,
each of which can be decomposed into at most convex parts. We present an
-approximation algorithm, for finding the translation of ,
which maximizes its area of overlap with . Our algorithm runs in
time, where is a constant that depends only on and .
This suggest that for polygons that are "close" to being convex, the problem
can be solved (approximately), in near linear time
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Lipoprotein particles in patients with pediatric Cushing disease and possible cardiovascular risks.
BackgroundCardiovascular (CV) complications are the most significant cause of mortality in adults with Cushing disease (CD); little is known about CV risk factors in children with CD. Measurement of lipoprotein particles by nuclear magnetic resonance (NMR) spectroscopy is a novel technology to assess CV risk. The objective of the current study is to analyze the NMR lipid profile in pediatric CD patients before and 1 year after remission.MethodsNMR lipid profile was obtained via the Vantera NMR analyzer, using frozen serum samples from 33 CD patients (mean age 13.8 ± 4.0 years) evaluated between 1997 and 2017 at the National Institutes of Health (NIH) Clinical Center (CC).ResultsGlycA (glycosylated acute-phase proteins), triglyceride-rich particles (TRLP medium and very small sizes), low-density lipoprotein (LDL) particles (LDLP total and large size), high-density lipoprotein (HDL) particles (HDLP total, medium and small sizes), total cholesterol, LDL-cholesterol, HDL-cholesterol, GlycA inflammatory biomarker, and apolipoprotein B and apolipoprotein A1 (ApoA1) concentrations showed statistically significant changes after remission of CD (p < 0.05).ConclusionIn our study population, most of the lipid variables improved post-CD remission, with the exception of HDL and ApoA1, indicating that NMR lipoprotein profile may be a helpful tool in assessing the CV risk in pediatric patients with CD
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