Influence of the Consciousness Energy Healing Treatment on the Physicochemical, Spectral, Thermal and Behavioral Properties of Sodium Selenate

Sodium selenate is an important nutraceutical/pharmaceutical compound used for the prevention and treatment of cancer, diabetes, inflammatory diseases, etc. The objective of the current study was to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing treatment) on physical, structural, thermal, and behavioral properties of sodium selenate using PXRD, PSD, FT-IR, UV-vis, TGA, and DSC analysis. Sodium selenate was divided into two parts – one part was control, while another part was treated with The Trivedi Effect® remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. The PXRD analysis showed a significant alteration of the crystallite size of the treated sample in the range of -34.41% to 33.27% compared to the control sample. However, the average crystallite size of the treated sample was significantly decreased by 7.85% compared with the control sample. The particle size of the treated sample at d10, d50, and d90 values were significantly reduced by 4.72%, 8.40%, and 32.33%, respectively compared with the control sample. Consequently, the surface area of the treated sample was significantly increased by 6.25% compared to the control sample. The control and treated FT-IR spectra indicated the presence of sharp and strong absorption bands at 886 cm-1 and 887 cm-1, respectively due to the Se=O stretching. The UV-vis spectroscopic analysis displayed that the wavelength for the maximum absorbance of the control and treated samples were at 204.6 and 204.9 nm, respectively. TGA analysis revealed that the total weight loss of the treated sample was reduced significantly by 5.64% compared with the control sample. The DSC analysis showed that the treated sample (94.63°C) had very close vaporization temperature than the control sample (94.97°C). But, the latent heat of vaporization was increased significantly in the treated sample by 7.06% compared to the control sample. Thus, The Trivedi Effect® - Energy of Consciousness Healing Treatment might lead to generate a new polymorphic form of sodium selenate, which would be more soluble, bioavailable, and thermally stable compared with the untreated sample. The Trivedi Effect® treated sodium selenate would be very useful to design better nutraceutical/pharmaceutical formulations that might offer better therapeutic response against inflammatory diseases, immunological disorders, stress, aging, infectious diseases, cancer, diabetes, heart diseases, Alzheimer’s disease, etc. https://www.trivedieffect.com/science/influence-of-the-consciousness-energy-healing-treatment-on-the-physicochemical-spectral-thermal-and-behavioral-properties-of-sodium-selenate http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=224&doi=10.11648/j.ajche.20170502.1

Characterization of Physical, Structural, Thermal, and Behavioral Properties of the Consciousness Healing Treated Zinc Chloride

Zinc chloride is an important pharmaceutical/nutraceutical compound used as a source of zinc. The objective of the current study was to investigate the impact of The Trivedi Effect®-Energy of Consciousness Healing Treatment (Biofield Energy Treatment) on physical, structural, thermal, and behavioral properties of zinc chloride using PXRD, PSD, FT-IR, UV-vis, and DSC analysis. Zinc chloride was divided into two parts – one part was control, while another part was treated with The Trivedi Effect® remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. A significant alteration of the crystallite size and relative intensities of the PXRD peaks was observed in The Trivedi Effect® treated sample compared with the control sample. A sharp peak at 2θ equal to 16.58° was observed in the control sample, but it was disappeared in the treated sample. The average crystallite size of the treated sample was significantly reduced by 21.31% compared with the control sample. The particle size values at d10, d50, and d90 were significantly decreased by 8.15%, 6.28%, and 5.26%, respectively in the treated sample compared with the control sample. The surface area of the treated sample was significantly increased by 7.14% compared with the control sample. The FT-IR spectroscopic analysis revealed that Zn-Cl stretching in the control and treated sample were found at 510 cm-1 and 511 cm-1, respectively. The UV-vis analysis exhibited that wavelength of the maximum absorbance (λmax) of both the control and treated samples was at 196 nm. The DSC analysis exhibited that the melting and decomposition temperature were decreased by 0.29% and 0.28%, respectively in the treated zinc chloride compared to the control sample. The latent heat of fusion of the treated sample (370.48 J/g) was increased significantly by 97.71% compared with the control sample (187.39 J/g). This results indicated that zinc chloride need more heat energy to undergo the process of melting after Biofield Energy Treatment. The enthalpy of decomposition of the treated sample was significantly decreased by 15.40% compared with the control sample. The current study anticipated that The Trivedi Effect®-Energy of Consciousness Healing Treatment might lead to produce a new polymorphic form of zinc chloride, which would be more soluble, bioavailable and latent heat of fusion compared with the untreated compound. Hence, the treated zinc chloride would be very useful to design better nutraceutical/pharmaceutical formulations that might offer better therapeutic response against inflammatory diseases, immunological disorders, aging, stress, cancer, etc. https://www.trivedieffect.com/science/characterization-of-physical-structural-thermal-and-behavioral-properties-of-the-consciousness-healing-treated-zinc-chloride http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=206&doi=10.11648/j.wjac.20170202.1

M & L Jaargang 34/5

Lynn De Clercq en Joris Nauwelaerts Een stedelijke arena van steen en beton: de verschillende gedaanten van het Gentse wintercircus. [An urban arena of concrete and stone: different aspects of the Ghent Winter Circus.]Door sommigen opgehemeld, door anderen verguisd. Het Gentse wintercircus, nog maar pas een eeuweling geworden, laat geen Gentenaar onberoerd. Het gebouw, opgetrokken op het einde van de 19de eeuw, is één van de laatste stenen circusgebouwen in Europa maar ook één van de eerste constructies in gewapend beton. Na de Tweede Wereldoorlog werd er een garage ondergebracht en ging het circusinterieur volledig verloren. Aan de lange leegstand komt binnenkort een einde. Het Gentse wintercircus, een gebouw met vele gedaanten, zal opnieuw in gebruik worden genomen. Lynn De Clercq en Joris Nauwelaerts reconstrueren de rijke geschiedenis van deze stedelijke arena en bieden een blik op haar toekomst.Pol Vanneste Wederopbouw van dorpskerken tussen Diksmuide en Nieuwpoort. Oorlogstrauma en kunsthistorische erfenis. [Reconstruction of parish churches between Diksmuide and Nieuwpoort. War trauma and art-historical heritage.]"Ene uitgestrekte verwarde woestijn." Zo zag de streek tussen Diksmuide en Nieuwpoort, die op de frontlinie lag, er uit na de Eerste Wereldoorlog. Hoe men in de jaren 1920 met de oorlogsruïnes en de verwoeste dorpen omging, wordt minutieus en gebaseerd op archieven, plannen en fotos beschreven door Pol Vanneste. De opties tot wederopbouw, historiserende reconstructie, heropbouw op een andere plaats of nieuwe architectuur omwille van het oorlogstrauma vaak geïnspireerd op de traditionele architectuur - waren vrij uiteenlopend en werden duidelijk gestuurd door de Koninklijke Commissie voor Monumenten, al was de stem van de plaatselijke overheden ook niet onbelangrijk.Heleen De Koster en Hilde Heynen De Aérogare 58. Theatraliteit en spektakel. [Aérogare 58. Theatricality and spectacle.]Hoe de Aérogare uit de bruisende expo 58-jaren werd geconcipieerd met onmiskenbare spektakelwaarde en theatraliteit, wordt opgeroepen door Heleen De Koster en Hilde Heynen op basis van nieuw archiefonderzoek en interviews met de betrokkenen. Interieur en meubilair waren zorgvuldig uitgekozen en evolueerden later volgens de nieuwere mode en stijlen. Omdat er buiten het karkas eigenlijk weinig concreets van bewaard bleef, is deze getuigenis des te belangrijker. Omwille van deze opeenvolgende gedaantes is het formuleren van een restauratieoptie voor deze transithal extra uitdagend.Kathleen Moermans, Maarten Van Dijck en Jef Vrelust De restauratie van de Stuckenholz-handkraan in Antwerpen. [Restauration of the Stuckenholz hand crane in Antwerp.]Technologie evolueert aan een indrukwekkende snelheid en zo geraakten de tot de verbeelding sprekende mastodonten op de kaaien in onbruik. Het Antwerpse stadsbestuur besloot om één kraan van elk type te bewaren als industrieel en technologisch archief, als onderdeel van de collectie van het MAS. De oudste maar krachtigste handbediende tientonskraan kwam als eerste aan de beurt en diende aldus als proeftuin voor de restauratie van de andere kranen, zoals door Kathleen Moermans, Jef Vrelust en Maarten Van Dijck wordt uiteengezet.Summar

Characterization of Physicochemical, Thermal, Structural, and Behavioral Properties of Magnesium Gluconate After Treatment with the Energy of Consciousness

Magnesium gluconate is a potent antioxidant and widely used for the prevention and treatment of hypomagnesia. The current research was aimed to investigate the impact of The Trivedi Effect® - Energy of Consciousness Healing Treatment on magnesium gluconate for the change in the physicochemical, structural, thermal and behavioral properties using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Magnesium gluconate was divided into two parts – one part was control without any Biofield Energy Treatment, while another part was treated with The Trivedi Effect® - Energy of Consciousness Healing Treatment remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. The PXRD analysis exhibited that the crystallite size of the treated sample was remarkably changed from - 24.96% to 99.98% compared with the control sample. The average crystallite size was significantly increased by 7.79% in the treated sample compared with the control sample. PSD analysis revealed that the particle sizes in The Trivedi Effect® Treated sample at d10, d50 and d90 values were decreased by 5.36%, 11.35% and 0.90%, respectively compared with the control sample. The surface area analysis revealed that surface area of the Biofield Energy Treated sample was significantly increased by 7.48% compared with the control sample. The FT-IR and UV-vis analysis showed that structure of the magnesium gluconate remained the same in both the treated and control samples. The TGA analysis revealed four steps thermal degradation of both the samples and the total weight loss of Biofield Energy Treated sample was increased by 0.12% compared with the control sample. The DSC analysis demonstrated that the melting temperature of the Biofield Energy Treated sample (171.29°C) was increased by 0.18% compared with the control sample (170.99°C). The latent heat of fusion was significantly increased by 27.09% in the treated sample compared with the control sample. The current study revealed that The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) might lead to a new polymorphic form of magnesium gluconate, which would be more soluble, bioavailable, and thermally stable compared with the untreated compound. The Biofield Treated sample could be more stable during manufacturing, delivery or storage conditions than the untreated sample. Hence, The Trivedi Effect® Treated magnesium gluconate would be very useful to design better nutraceutical and/or pharmaceutical formulations that might offer better therapeutic responses against inflammatory diseases, immunological disorders, stress, aging, and other chronic infections. Source: https://www.trivedieffect.com/science/characterization-of-physicochemical-thermal-structural-and-behavioral-properties-of-magnesium-gluconate-after-treatment-with-the-energy-of-consciousness http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=330&doi=10.11648/j.ijpc.20170301.1

Effect of the Energy of Consciousness (The Trivedi Effect®) on the Structural Properties and Isotopic Abundance Ratio of Magnesium Gluconate Using LC-MS and NMR Spectroscopy

Magnesium gluconate has the wide application for the prevention and treatment of hypomagnesemia. The objective of the current study was to investigate the effect of The Trivedi Effect® - Energy of Consciousness Healing Treatment (Biofield Energy Healing Treatment) on magnesium gluconate for the change in the structural properties and isotopic abundance ratio (PM+1/PM) using LC-MS and NMR spectroscopy. Magnesium gluconate was divided into two parts – one part was control, and another part was treated with The Trivedi Effect® - Biofield Energy Healing Treatment remotely by seven renowned Biofield Energy Healers and defined as The Trivedi Effect® Treated sample. The LC-MS analysis of both the control and treated samples revealed the presence of the mass of the protonated magnesium gluconate at m/z 415 at the retention time of 1.53 minutes with almost similar fragmentation pattern. The relative peak intensities of the fragment ions of the treated sample were significantly altered compared with the control sample. The proton and carbon signals for CH, CH2 and CO groups in the proton and carbon NMR spectra were observed almost similar for the control and the treated samples. The isotopic abundance ratio analysis revealed that the percentage of the isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 17O/16O or 25Mg/24Mg) was significantly increased in treated sample by 80.38%, compared with the control sample. Briefly, 13C, 2H, 17O, and 25Mg contributions from (C12H23MgO14)+ to m/z 416; 18O and 26Mg contributions from (C12H23MgO14)+ to m/z 417 in the treated sample were significantly increased compared with the control sample. Thus, the treated magnesium gluconate could be valuable for designing better pharmaceutical and/or nutraceutical formulations through its changed physicochemical and thermal properties, which might be providing better therapeutic response against various diseases such as diabetes mellitus, allergy, aging, inflammatory diseases, immunological disorders, and other chronic infections. The Trivedi Effect® treated magnesium gluconate might be supportive to design the novel potent enzyme inhibitors using its kinetic isotope effects. Source: https://www.trivedieffect.com/science/effect-of-the-energy-of-consciousness-the-trivedi-effect-on-the-structural-properties-and-isotopic-abundance-ratio-of-magnesium-gluconate-using-lc-ms-and-nmr-spectroscopy http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=110&doi=10.11648/j.ab.20170501.1

Factor Xa Generation by Computational Modeling: An Additional Discriminator to Thrombin Generation Evaluation

Factor (f)Xa is a critical enzyme in blood coagulation that is responsible for the initiation and propagation of thrombin generation. Previously we have shown that analysis of computationally generated thrombin profiles is a tool to investigate hemostasis in various populations. In this study, we evaluate the potential of computationally derived time courses of fXa generation as another approach for investigating thrombotic risk. Utilizing the case (n = 473) and control (n = 426) population from the Leiden Thrombophilia Study and each individual's plasma protein factor composition for fII, fV, fVII, fVIII, fIX, fX, antithrombin and tissue factor pathway inhibitor, tissue factor-initiated total active fXa generation was assessed using a mathematical model. FXa generation was evaluated by the area under the curve (AUC), the maximum rate (MaxR) and level (MaxL) and the time to reach these, TMaxR and TMaxL, respectively. FXa generation was analyzed in the entire populations and in defined subgroups (by sex, age, body mass index, oral contraceptive use). The maximum rates and levels of fXa generation occur over a 10- to 12- fold range in both cases and controls. This variation is larger than that observed with thrombin (3–6 fold) in the same population. The greatest risk association was obtained using either MaxR or MaxL of fXa generation; with an ∼2.2 fold increased risk for individuals exceeding the 90th percentile. This risk was similar to that of thrombin generation(MaxR OR 2.6). Grouping defined by oral contraceptive (OC) use in the control population showed the biggest differences in fXa generation; a >60% increase in the MaxR upon OC use. FXa generation can distinguish between a subset of individuals characterized by overlapping thrombin generation profiles. Analysis of fXa generation is a phenotypic characteristic which may prove to be a more sensitive discriminator than thrombin generation among all individuals

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

Comprehensive RNA dataset of tissue and plasma from patients with esophageal cancer or precursor lesions

In the past decades, the incidence of esophageal adenocarcinoma has increased dramatically in Western populations. Better understanding of disease etiology along with the identification of novel prognostic and predictive biomarkers are urgently needed to improve the dismal survival probabilities. Here, we performed comprehensive RNA (coding and non-coding) profiling in various samples from 17 patients diagnosed with esophageal adenocarcinoma, high-grade dysplastic or non-dysplastic Barrett's esophagus. Per patient, a blood plasma sample, and a healthy and disease esophageal tissue sample were included. In total, this comprehensive dataset consists of 102 sequenced libraries from 51 samples. Based on this data, 119 expression profiles are available for three biotypes, including miRNA (51), mRNA (51) and circRNA (17). This unique resource allows for discovery of novel biomarkers and disease mechanisms, comparison of tissue and liquid biopsy profiles, integration of coding and non-coding RNA patterns, and can serve as a validation dataset in other RNA landscaping studies. Moreover, structural RNA differences can be identified in this dataset, including protein coding mutations, fusion genes, and circular RNAs